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Microbiology

D-Index
83
Citations
19723
World Ranking
1017
National Ranking
62

Overview

Steffen Backert is affiliated with the University of Erlangen-Nuremberg in Germany. Their research primarily spans the field of Medicine, with a particular focus on Surgery, Immunology, Molecular Biology, Infectious Diseases, and Food Science as subfields of study.

Their scientific work explores several main topics, including:

  • Helicobacter pylori-related gastroenterology studies
  • Galectins and Cancer Biology
  • Salmonella and Campylobacter epidemiology
  • Veterinary medicine and infectious diseases
  • Viral gastroenteritis research and epidemiology
  • Barrier Structure and Function Studies
  • Vibrio bacteria research studies

Steffen Backert has published extensively in journals such as:

  • Current topics in microbiology and immunology
  • Cancers
  • Biomolecules
  • Pathogens
  • Gut Microbes

Some recent papers authored or co-authored by Backert include:

  • "Human Campylobacteriosis-A Serious Infectious Threat in a One Health Perspective" (2021), published in Current topics in microbiology and immunology
  • "Four Chromosomal Type IV Secretion Systems in Helicobacter pylori: Composition, Structure and Function" (2020), published in Frontiers in Microbiology
  • "A single-nucleotide polymorphism in Helicobacter pylori promotes gastric cancer development" (2023), published in Cell Host & Microbe
  • "Campylobacter Virulence Factors and Molecular Host-Pathogen Interactions" (2021), published in Current topics in microbiology and immunology
  • "Toll-like Receptor 5 Activation by the CagY Repeat Domains of Helicobacter pylori" (2020), published in Cell Reports

The scientist frequently collaborates with colleagues, notably including:

  • Nicole Tegtmeyer
  • Irshad Sharafutdinov
  • Bodo Linz
  • Heinrich Sticht
  • Michael Vieth

Best Publications

  • Helicobacter exploits integrin for type IV secretion and kinase activation

    Terry Kwok;Dana Zabler;Sylwia Urman;Manfred Rohde

  • NF-κB activation and potentiation of proinflammatory responses by the Helicobacter pylori CagA protein

    Sabine Brandt;Terry Kwok;Roland Hartig;Wolfgang König

  • Translocation of the Helicobacter pylori CagA protein in gastric epithelial cells by a type IV secretion apparatus.

    Steffen Backert;Elke Ziska;Volker Brinkmann;Ursula Zimny-Arndt

  • Type IV secretion systems and their effectors in bacterial pathogenesis

    Steffen Backert;Thomas F Meyer

  • Src Is the Kinase of the Helicobacter pylori CagA Protein in Vitro and in Vivo

    Matthias Selbach;Stefan Moese;Christof R. Hauck;Thomas F. Meyer

  • Role of type IV secretion in Helicobacter pylori pathogenesis

    Steffen Backert;Matthias Selbach

  • Type IV secretion in Gram-negative and Gram-positive bacteria.

    Elisabeth Grohmann;Peter J. Christie;Gabriel Waksman;Steffen Backert

  • Helicobacter pylori HtrA is a new secreted virulence factor that cleaves E-cadherin to disrupt intercellular adhesion

    Benjamin Hoy;Martin Löwer;Christiane Weydig;Gert Carra

  • Role of the cag-pathogenicity island encoded type IV secretion system in Helicobacter pylori pathogenesis

    Nicole Tegtmeyer;Silja Wessler;Steffen Backert;Steffen Backert

  • Phosphorylation of tyrosine 972 of the Helicobacter pylori CagA protein is essential for induction of a scattering phenotype in gastric epithelial cells.

    Steffen Backert;Stefan Moese;Matthias Selbach;Volker Brinkmann

  • The Helicobacter pylori CagA protein induces cortactin dephosphorylation and actin rearrangement by c-Src inactivation.

    Matthias Selbach;Stefan Moese;Robert Hurwitz;Christof R. Hauck

  • Activation of Abl by Helicobacter pylori: a novel kinase for CagA and crucial mediator of host cell scattering.

    Ina Tammer;Sabine Brandt;Roland Hartig;Wolfgang König

  • The Versatility of Helicobacter pylori CagA Effector Protein Functions: The Master Key Hypothesis

    Steffen Backert;Steffen Backert;Nicole Tegtmeyer;Matthias Selbach

  • Helicobacter pylori adhesin HopQ engages in a virulence-enhancing interaction with human CEACAMs

    Anahita Javaheri;Tobias Kruse;Kristof Moonens;Raquel Mejías-Luque

  • Pathogenesis of Helicobacter pylori infection

    Steffen Backert;Matthias Neddermann;Gunter Maubach;Michael Naumann

  • c-Src and c-Abl kinases control hierarchic phosphorylation and function of the CagA effector protein in Western and East Asian Helicobacter pylori strains

    Doreen Mueller;Nicole Tegtmeyer;Sabine Brandt;Yoshio Yamaoka

  • Biochemical and functional characterization of Helicobacter pylori vesicles

    Annelie Olofsson;Anna Vallström;Katja Petzold;Nicole Tegtmeyer

  • Composition, structure and function of the Helicobacter pylori cag pathogenicity island encoded type IV secretion system

    Steffen Backert;Nicole Tegtmeyer;Wolfgang Fischer

  • What a disorder: proinflammatory signaling pathways induced by Helicobacter pylori.

    Steffen Backert;Michael Naumann

  • The functional interplay of Helicobacter pylori factors with gastric epithelial cells induces a multi-step process in pathogenesis.

    Gernot Posselt;Steffen Backert;Silja Wessler

Frequent Co-Authors

Thomas F. Meyer
Thomas F. Meyer Max Planck Institute for Infection Biology
Wolfgang König
Wolfgang König Otto-von-Guericke University Magdeburg
Matthias Selbach
Matthias Selbach Max Delbrück Center for Molecular Medicine
Norbert Sewald
Norbert Sewald Bielefeld University
Heinrich Sticht
Heinrich Sticht University of Erlangen-Nuremberg
Michael Naumann
Michael Naumann Otto-von-Guericke University Magdeburg
Markus Gerhard
Markus Gerhard Technical University of Munich
Markus M. Heimesaat
Markus M. Heimesaat Charité - University Medicine Berlin
Yoshio Yamaoka
Yoshio Yamaoka Oita University

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