D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 57 Citations 9,871 128 World Ranking 1360 National Ranking 82

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Bacteria

Steffen Backert focuses on CagA, Microbiology, Secretion, Helicobacter pylori and Virulence. His study in CagA is interdisciplinary in nature, drawing from both Molecular biology, Cancer research, Kinase and Phosphorylation. His Microbiology study combines topics from a wide range of disciplines, such as Virulence factor, Yersinia enterocolitica, Proteases, Campylobacter jejuni and Bacterial adhesin.

His Secretion research includes elements of Signal transduction, Pilus and Effector. His work carried out in the field of Helicobacter pylori brings together such families of science as Immunology and Pathogenicity island. His Virulence research integrates issues from Plasma protein binding and Host cell membrane.

His most cited work include:

  • Helicobacter exploits integrin for type IV secretion and kinase activation (490 citations)
  • NF-κB activation and potentiation of proinflammatory responses by the Helicobacter pylori CagA protein (400 citations)
  • Src Is the Kinase of the Helicobacter pylori CagA Protein in Vitro and in Vivo (369 citations)

What are the main themes of his work throughout his whole career to date?

Steffen Backert mainly investigates Microbiology, Helicobacter pylori, CagA, Secretion and Cell biology. His studies in Microbiology integrate themes in fields like Signal transduction, Campylobacter jejuni, Campylobacter and Virulence. His Helicobacter pylori research is multidisciplinary, incorporating perspectives in TLR2, Immunology, Immune system, Cell adhesion molecule and Gastric mucosa.

As part of the same scientific family, he usually focuses on CagA, concentrating on Phosphorylation and intersecting with Tyrosine. His Secretion research focuses on subjects like Effector, which are linked to ABL. His work in Cell biology addresses issues such as Adherens junction, which are connected to fields such as Occludin.

He most often published in these fields:

  • Microbiology (44.00%)
  • Helicobacter pylori (38.67%)
  • CagA (36.44%)

What were the highlights of his more recent work (between 2018-2021)?

  • Helicobacter pylori (38.67%)
  • Microbiology (44.00%)
  • Campylobacter jejuni (16.00%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Helicobacter pylori, Microbiology, Campylobacter jejuni, Virulence and Serine protease. His Helicobacter pylori study incorporates themes from CagA, Secretion, Immune system, Receptor and Molecular biology. Steffen Backert has researched CagA in several fields, including Tyrosine kinase, Integrin, Cortactin, Cytoskeleton and Effector.

Steffen Backert works mostly in the field of Secretion, limiting it down to concerns involving TLR5 and, occasionally, Activator, Pathogenic bacteria, Signal transduction and Intracellular signal transduction. His Microbiology study combines topics in areas such as Mutant and Flagellin. His studies examine the connections between Virulence and genetics, as well as such issues in Bacterial cell structure, with regards to Toxin and Gastric Diseases.

Between 2018 and 2021, his most popular works were:

  • Campylobacter jejuni enters gut epithelial cells and impairs intestinal barrier function through cleavage of occludin by serine protease HtrA (25 citations)
  • Expression of CEACAM1 or CEACAM5 in AZ-521 cells restores the type IV secretion deficiency for translocation of CagA by Helicobacter pylori. (18 citations)
  • Immunopathological properties of the Campylobacter jejuni flagellins and the adhesin CadF as assessed in a clinical murine infection model (17 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Bacteria

His primary areas of study are Helicobacter pylori, Microbiology, Virulence, Campylobacter jejuni and Immune system. Steffen Backert interconnects CagA, Secretion, TLR2, Molecular biology and Effector in the investigation of issues within Helicobacter pylori. His CagA study typically links adjacent topics like Cortactin.

His Secretion research is multidisciplinary, relying on both Receptor, Activator, Pathogenic bacteria and TLR5. The Effector study combines topics in areas such as Toxin, Cell adhesion molecule, Phosphorylation, Gastric Diseases and Kinase. His Campylobacter jejuni research incorporates themes from Host–pathogen interaction, Bacterial adhesin and Flagellin.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Helicobacter exploits integrin for type IV secretion and kinase activation

Terry Kwok;Dana Zabler;Sylwia Urman;Manfred Rohde.
Nature (2007)

630 Citations

NF-κB activation and potentiation of proinflammatory responses by the Helicobacter pylori CagA protein

Sabine Brandt;Terry Kwok;Roland Hartig;Wolfgang König.
Proceedings of the National Academy of Sciences of the United States of America (2005)

616 Citations

Translocation of the Helicobacter pylori CagA protein in gastric epithelial cells by a type IV secretion apparatus.

Steffen Backert;Elke Ziska;Volker Brinkmann;Ursula Zimny-Arndt.
Cellular Microbiology (2000)

489 Citations

Type IV secretion systems and their effectors in bacterial pathogenesis

Steffen Backert;Thomas F Meyer.
Current Opinion in Microbiology (2006)

485 Citations

Src Is the Kinase of the Helicobacter pylori CagA Protein in Vitro and in Vivo

Matthias Selbach;Stefan Moese;Christof R. Hauck;Thomas F. Meyer.
Journal of Biological Chemistry (2002)

482 Citations

Role of type IV secretion in Helicobacter pylori pathogenesis

Steffen Backert;Matthias Selbach.
Cellular Microbiology (2008)

355 Citations

Phosphorylation of tyrosine 972 of the Helicobacter pylori CagA protein is essential for induction of a scattering phenotype in gastric epithelial cells.

Steffen Backert;Stefan Moese;Matthias Selbach;Volker Brinkmann.
Molecular Microbiology (2008)

290 Citations

Activation of Abl by Helicobacter pylori: a novel kinase for CagA and crucial mediator of host cell scattering.

Ina Tammer;Sabine Brandt;Roland Hartig;Wolfgang König.
Gastroenterology (2007)

271 Citations

The Helicobacter pylori CagA protein induces cortactin dephosphorylation and actin rearrangement by c-Src inactivation

Matthias Selbach;Stefan Moese;Robert Hurwitz;Christof R. Hauck.
The EMBO Journal (2003)

262 Citations

Role of the cag-pathogenicity island encoded type IV secretion system in Helicobacter pylori pathogenesis

Nicole Tegtmeyer;Silja Wessler;Steffen Backert;Steffen Backert.
FEBS Journal (2011)

260 Citations

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