Masanori Hatakeyama mainly investigates CagA, Helicobacter pylori, Tyrosine phosphorylation, Cancer research and Secretion. His CagA research is multidisciplinary, relying on both Kinase, Proto-oncogene tyrosine-protein kinase Src, Protein tyrosine phosphatase, Phosphorylation and Microbiology. Masanori Hatakeyama works mostly in the field of Phosphorylation, limiting it down to topics relating to Molecular biology and, in certain cases, Tyrosine.
His Microbiology study incorporates themes from Transport protein, Cell biology and Gene product. The study incorporates disciplines such as Cancer stem cell, Cancer, CD44 and Immunology in addition to Helicobacter pylori. His Cancer research research integrates issues from Signal transduction, Gastric mucosa and Transcription factor.
The scientist’s investigation covers issues in CagA, Helicobacter pylori, Molecular biology, Cancer research and Tyrosine phosphorylation. His CagA research is multidisciplinary, incorporating perspectives in Kinase, Protein tyrosine phosphatase, Phosphorylation, Carcinogenesis and Secretion. His research in Helicobacter pylori intersects with topics in Cancer, Virology, Immunology, Microbiology and Gastric mucosa.
His studies deal with areas such as Transactivation, Complementary DNA, Peptide sequence, Gene and Gene product as well as Molecular biology. His Cancer research research includes elements of Cell culture, Neoplastic transformation and STAT protein. His Tyrosine phosphorylation research incorporates elements of Phosphatase and Tight junction.
His scientific interests lie mostly in CagA, Helicobacter pylori, Cancer research, Secretion and Cancer. His CagA research incorporates themes from Tyrosine phosphorylation, Protein tyrosine phosphatase, Phosphorylation, Carcinogenesis and Molecular biology. Within one scientific family, Masanori Hatakeyama focuses on topics pertaining to Phosphatase under Tyrosine phosphorylation, and may sometimes address concerns connected to Wnt signaling pathway, Parafibromin and Tyrosine.
The Helicobacter pylori study combines topics in areas such as Virology, Microbiology, Gene, Gastric mucosa and Kinase. His work deals with themes such as Inflammation, Receptor, Gastric carcinogenesis and Neoplastic transformation, which intersect with Cancer research. His Secretion study combines topics from a wide range of disciplines, such as Heat shock protein, Heat shock, Phenotype, Antigen and Ectopic expression.
Masanori Hatakeyama mainly focuses on Helicobacter pylori, CagA, Secretion, Cancer research and Carcinogenesis. Masanori Hatakeyama combines subjects such as Gene duplication, Molecular biology, Immunology and Gastric mucosa with his study of Helicobacter pylori. His biological study spans a wide range of topics, including Antigen and Virology.
Masanori Hatakeyama interconnects Inflammation, Tyrosine phosphorylation, Morphogen and Hedgehog, GLI1 in the investigation of issues within Cancer research. His Tyrosine phosphorylation research focuses on Phosphatase and how it connects with Protein tyrosine phosphatase. In the subject of general Carcinogenesis, his work in Neoplastic transformation is often linked to Fusobacterium nucleatum, thereby combining diverse domains of study.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein.
Hideaki Higashi;Ryouhei Tsutsumi;Syuichi Muto;Toshiro Sugiyama.
Oncogenic mechanisms of the Helicobacter pylori CagA protein
Nature Reviews Cancer (2004)
Biological activity of the Helicobacter pylori virulence factor CagA is determined by variation in the tyrosine phosphorylation sites
Hideaki Higashi;Ryouhei Tsutsumi;Akiko Fujita;Shiho Yamazaki.
Proceedings of the National Academy of Sciences of the United States of America (2002)
Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse
Naomi Ohnishi;Hitomi Yuasa;Shinya Tanaka;Hirofumi Sawa.
Proceedings of the National Academy of Sciences of the United States of America (2008)
Helicobacter pylori CagA interacts with E-cadherin and deregulates the β-catenin signal that promotes intestinal transdifferentiation in gastric epithelial cells
N Murata-Kamiya;Y Kurashima;Y Teishikata;Y Yamahashi.
Activation of β-catenin by carcinogenic Helicobacter pylori
Aime T. Franco;Dawn A. Israel;Mary K. Washington;Uma Krishna.
Proceedings of the National Academy of Sciences of the United States of America (2005)
Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity
Iraj Saadat;Hideaki Higashi;Chikashi Obuse;Mayumi Umeda.
Attenuation of Helicobacter pylori CagA·SHP-2 Signaling by Interaction between CagA and C-terminal Src Kinase
Ryouhei Tsutsumi;Hideaki Higashi;Megumi Higuchi;Masato Okada.
Journal of Biological Chemistry (2003)
Helicobacter pylori CagA induces Ras-independent morphogenetic response through SHP-2 recruitment and activation.
Hideaki Higashi;Akihiro Nakaya;Ryouhei Tsutsumi;Kazuyuki Yokoyama.
Journal of Biological Chemistry (2004)
Helicobacter pylori CagA and Gastric Cancer: A Paradigm for Hit-and-Run Carcinogenesis
Cell Host & Microbe (2014)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: