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Tadatsugu Taniguchi

Tadatsugu Taniguchi

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Molecular Biology
Japan
2026
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Genetics and Molecular Biology
Japan
2024

D-Index & Metrics

Molecular Biology

D-Index
140
Citations
100326
World Ranking
125
National Ranking
10

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in Japan Leader Award
  • 2025 - Research.com Molecular Biology in Japan Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Japan Leader Award
  • 2023 - Research.com Genetics and Molecular Biology in Japan Leader Award
  • 2023 - Research.com Molecular Biology in Japan Leader Award
  • 2022 - Research.com Genetics and Molecular Biology in Japan Leader Award
  • 2003 - Member of the National Academy of Sciences
  • 1991 - Robert Koch Prize

Overview

Tadatsugu Taniguchi is affiliated with the University of Tokyo in Japan and has contributed extensively to the fields of Immunology and Microbiology as well as Medicine. Their research interests encompass Immunology, Psychiatry and Mental Health, Molecular Biology, Oncology, and Clinical Biochemistry.

Their published works explore key topics in immune mechanisms, particularly in cancer and inflammatory contexts. Main areas of study include:

  • Immune cells in cancer
  • Immune Response and Inflammation
  • Cancer, Stress, Anesthesia, and Immune Response
  • Immune Cell Function and Interaction
  • Advanced Glycation End Products research
  • Nanoplatforms for cancer theranostics
  • Chemokine receptors and signaling

Taniguchi's frequent co-authors include Hideyuki Yanai, Sho Hangai, Sana Hibino, Yoshitaka Kimura, and Tatsuma Ban, reflecting collaborative efforts across immunology and molecular biology.

Prominent venues for their publications are:

  • Proceedings of the National Academy of Sciences
  • Nature Immunology
  • Nature Communications
  • The Journal of Experimental Medicine
  • International Immunology

Significant papers authored or co-authored by Taniguchi include:

  • "Orchestration of myeloid-derived suppressor cells in the tumor microenvironment by ubiquitous cellular protein TCTP released by tumor cells" (2021), Nature Immunology
  • "Genetic and chemical inhibition of IRF5 suppresses pre-existing mouse lupus-like disease" (2021), Nature Communications
  • "Tumor cell-derived spermidine is an oncometabolite that suppresses TCR clustering for intratumoral CD8 + T cell activation" (2023), Proceedings of the National Academy of Sciences
  • "HMGB1-mediated chromatin remodeling attenuates Il24 gene expression for the protection from allergic contact dermatitis" (2020), Proceedings of the National Academy of Sciences
  • "Damage-associated molecular patterns and Toll-like receptors in the tumor immune microenvironment" (2021), International Immunology

Taniguchi has been recognized with awards such as the Robert Koch Prize in 1991 and election as a Member of the National Academy of Sciences in 2003.

Best Publications

  • Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

    Koji Atarashi;Takeshi Tanoue;Tatsuichiro Shima;Akemi Imaoka

  • Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota

    Koji Atarashi;Takeshi Tanoue;Kenshiro Oshima;Wataru Suda

  • Noxa, a BH3-Only Member of the Bcl-2 Family and Candidate Mediator of p53-Induced Apoptosis

    Eri Oda;Rieko Ohki;Hideki Murasawa;Jiro Nemoto

  • Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts.

    Hiroshi Takayanagi;Sunhwa Kim;Takako Koga;Takako Koga;Hiroshi Nishina

  • Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

    Toshio Hirano;Kiyoshi Yasukawa;Hisashi Harada;Tetsuya Taga

  • IRF-7 is the master regulator of type-I interferon-dependent immune responses

    Kenya Honda;Hideyuki Yanai;Hideo Negishi;Masataka Asagiri

  • IRF family of transcription factors as regulators of host defense

    Tadatsugu Taniguchi;Kouetsu Ogasawara;and Akinori Takaoka;Nobuyuki Tanaka

  • DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

    Akinori Takaoka;Zhichao Wang;Myoung Kwon Choi;Hideyuki Yanai

  • IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors.

    Kenya Honda;Tadatsugu Taniguchi

  • Distinct and Essential Roles of Transcription Factors IRF-3 and IRF-7 in Response to Viruses for IFN-α/β Gene Induction

    Mitsuharu Sato;Hirofumi Suemori;Naoki Hata;Masataka Asagiri

  • A new protein containing an SH2 domain that inhibits JAK kinases

    Takaho A. Endo;Masaaki Masuhara;Masahiro Yokouchi;Ritsu Suzuki

  • Identification of a Member of the MAPKKK Family as a Potential Mediator of TGF-β Signal Transduction

    Kyoko Yamaguchi;Kyoko Shirakabe;Hiroshi Shibuya;Kenji Irie

  • Type I Inteferon Gene Induction by the Interferon Regulatory Factor Family of Transcription Factors

    Kenya Honda;Akinori Takaoka;Tadatsugu Taniguchi

  • Structure and expression of a cloned cDNA for human interleukin-2

    Tadatsugu Taniguchi;Hiroshi Matsui;Takashi Fujita;Chikako Takaoka

  • T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-gamma.

    Hiroshi Takayanagi;Kouetsu Ogasawara;Shigeaki Hida;Tomoki Chiba

  • Association of rheumatoid arthritis and primary osteoarthritis with changes in the glycosylation pattern of total serum IgG.

    R. B. Parekh;R. A. Dwek;B. J. Sutton;D. L. Fernandes

  • Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor

    Katsuhiko Yamasaki;Tetsuya Taga;Yuuichi Hirata;Hideo Yawata

  • The IRF Family Transcription Factors in Immunity and Oncogenesis

    Tomohiko Tamura;Hideyuki Yanai;David Savitsky;Tadatsugu Taniguchi

  • Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors

    Akinori Takaoka;Hideyuki Yanai;Seiji Kondo;Gordon Duncan

  • Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-β gene regulatory elements

    Masaaki Miyamoto;Takashi Fujita;Yoko Kimura;Mitsuo Maruyama

Frequent Co-Authors

Kenya Honda
Kenya Honda Keio University
Akinori Takaoka
Akinori Takaoka Hokkaido University
Takashi Fujita
Takashi Fujita Kyoto University
Hisashi Harada
Hisashi Harada Virginia Commonwealth University
Yoshihide Asano
Yoshihide Asano University of Tokyo
Hiroshi Takayanagi
Hiroshi Takayanagi University of Tokyo
Yasuhiro Minami
Yasuhiro Minami Kobe University
Tomohiko Tamura
Tomohiko Tamura Yokohama City University
Yusuke Ohba
Yusuke Ohba Hokkaido University
Kouetsu Ogasawara
Kouetsu Ogasawara Tohoku University

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