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Kenya Honda

Kenya Honda

D-Index & Metrics

Immunology

D-Index
89
Citations
65399
World Ranking
1093
National Ranking
40

Overview

Kenya Honda is affiliated with Keio University in Japan and has contributed extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research spans multiple subfields, including Molecular Biology, Epidemiology, Infectious Diseases, Immunology, and Genetics.

Their primary focus lies in topics related to gut microbiota and health, with additional emphasis on Clostridium difficile and Clostridium perfringens research, immune cell function and interaction, bacteriophages and microbial interactions, gastrointestinal motility and disorders, IL-33, ST2, and ILC pathways, as well as probiotics and fermented foods.

Kenya Honda has published research in several frequently encountered venues, such as:

  • Nature
  • Cell
  • Gastroenterology
  • The Journal of Immunology
  • Nature Microbiology

Some of the recent notable papers include:

  • "Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians" (2021, Nature)
  • "Endogenous murine microbiota member Faecalibaculum rodentium and its human homologue protect from intestinal tumour growth" (2020, Nature Microbiology)
  • "Targeted suppression of human IBD-associated gut microbiota commensals by phage consortia for treatment of intestinal inflammation" (2022, Cell)
  • "Microbiota modulate sympathetic neurons via a gut-brain circuit" (2020, Nature)
  • "Microbiota imbalance induced by dietary sugar disrupts immune-mediated protection from metabolic syndrome" (2022, Cell)

Throughout their career, Kenya Honda has collaborated frequently with fellow researchers including Koji Atarashi, Wataru Suda, Masahira Hattori, Kozue Takeshita, and Takeshi Tanoue.

Best Publications

  • Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

    Yukihiro Furusawa;Yuuki Obata;Shinji Fukuda;Takaho A. Endo

  • Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

    Ivaylo I. Ivanov;Koji Atarashi;Nicolas Manel;Eoin L. Brodie

  • Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

    Koji Atarashi;Takeshi Tanoue;Tatsuichiro Shima;Akemi Imaoka

  • Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota

    Koji Atarashi;Takeshi Tanoue;Kenshiro Oshima;Wataru Suda

  • IRF-7 is the master regulator of type-I interferon-dependent immune responses

    Kenya Honda;Hideyuki Yanai;Hideo Negishi;Masataka Asagiri

  • Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

    Shin Yoshimoto;Tze Mun Loo;Tze Mun Loo;Koji Atarashi;Hiroaki Kanda

  • The microbiota in adaptive immune homeostasis and disease

    Kenya Honda;Dan R. Littman

  • DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

    Akinori Takaoka;Zhichao Wang;Myoung Kwon Choi;Hideyuki Yanai

  • IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors.

    Kenya Honda;Tadatsugu Taniguchi

  • Type I Inteferon Gene Induction by the Interferon Regulatory Factor Family of Transcription Factors

    Kenya Honda;Akinori Takaoka;Tadatsugu Taniguchi

  • Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors

    Akinori Takaoka;Hideyuki Yanai;Seiji Kondo;Gordon Duncan

  • Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction.

    Kenya Honda;Yusuke Ohba;Yusuke Ohba;Hideyuki Yanai;Hideo Negishi

  • Th17 Cell Induction by Adhesion of Microbes to Intestinal Epithelial Cells

    Koji Atarashi;Takeshi Tanoue;Minoru Ando;Nobuhiko Kamada

  • Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence.

    Akinori Takaoka;Sumio Hayakawa;Hideyuki Yanai;Dagmar Stoiber;Dagmar Stoiber

  • A defined commensal consortium elicits CD8 T cells and anti-cancer immunity

    Takeshi Tanoue;Satoru Morita;Damian R. Plichta;Ashwin N. Skelly

  • ATP drives lamina propria T H 17 cell differentiation

    Koji Atarashi;Junichi Nishimura;Tatsuichiro Shima;Yoshinori Umesaki

  • IRF4 Transcription Factor-Dependent CD11b+ Dendritic Cells in Human and Mouse Control Mucosal IL-17 Cytokine Responses

    Andreas Schlitzer;Naomi McGovern;Pearline Teo;Teresa Zelante

  • Ectopic colonization of oral bacteria in the intestine drives TH1 cell induction and inflammation

    Koji Atarashi;Wataru Suda;Wataru Suda;Wataru Suda;Chengwei Luo;Chengwei Luo;Takaaki Kawaguchi

  • The microbiota regulates type 2 immunity through RORγt+ T cells

    Caspar Ohnmacht;Joo Hong Park;Sascha Cording;James B. Wing

  • Two FOXP3 + CD4 + T cell subpopulations distinctly control the prognosis of colorectal cancers

    Takuro Saito;Hiroyoshi Nishikawa;Hisashi Wada;Yuji Nagano

  • Correction: Corrigendum: A subpopulation of high IL-21-producing CD4+ T cells in Peyer’s Patches is induced by the microbiota and regulates germinal centers

    Leigh Jones;Wen Qi Ho;Sze Ying;Lakshmi Ramakrishna

  • HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses

    Hideyuki Yanai;Tatsuma Ban;ZhiChao Wang;Myoung Kwon Choi

Frequent Co-Authors

Masahira Hattori
Masahira Hattori Waseda University
Tadatsugu Taniguchi
Tadatsugu Taniguchi University of Tokyo
Kenshiro Oshima
Kenshiro Oshima University of Tokyo
Kiyoshi Takeda
Kiyoshi Takeda Osaka University
Akinori Takaoka
Akinori Takaoka Hokkaido University
Yusuke Ohba
Yusuke Ohba Hokkaido University
Koji Hase
Koji Hase Keio University
Shohei Hori
Shohei Hori University of Tokyo
Masahiro Yamamoto
Masahiro Yamamoto Osaka University

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