World's Best Scientists 2026 revealed!
Hiroshi Kiyono

Hiroshi Kiyono

Award Badge
Immunology
Japan
2023

D-Index & Metrics

Immunology

D-Index
127
Citations
52801
World Ranking
264
National Ranking
12

Research.com Recognitions

  • 2023 - Research.com Immunology in Japan Leader Award
  • 2022 - Research.com Immunology in Japan Leader Award

Overview

Hiroshi Kiyono is affiliated with the University of Tokyo in Japan and conducts research primarily in the field of Medicine. Their work spans multiple subfields, including Health, Infectious Diseases, Epidemiology, Hepatology, and Pediatrics, Perinatology, and Child Health.

Their research themes cover a diversity of topics, with frequent emphasis on Vaccine Coverage and Hesitancy, Hepatitis Viruses Studies and Epidemiology, Viral gastroenteritis research and epidemiology, Global Maternal and Child Health, Viral Infections and Outbreaks Research, Pneumonia and Respiratory Infections, and Bacterial Infections and Vaccines.

Recent published papers by Hiroshi Kiyono include:

  • Strengthening surveillance in Ghana against public health emergencies of international concern, 2022, Tropical Medicine and Health
  • Endotoxin-Free Stx2B-C-CPE Vaccine and Its Optimized Adjuvant Regimen for Preventing Food Poisoning, 2023, Frontiers in Bioscience-Landmark
  • Lymphoid-Tissue-Resident Commensal Bacteria Promote Members of the IL-10 Cytokine Family to Establish Mutualism, 2020, UNC Libraries
  • Nanogel-Based PspA Intranasal Vaccine Prevents Invasive Disease and Nasal Colonization by Streptococcus pneumoniae, 2020, UNC Libraries

Hiroshi Kiyono has collaborated frequently with several coauthors, including Jun Kunisawa, with whom they have worked on at least three publications. Other frequent collaborators include David W. Pascual, M Adachi, Kiyosu Taniguchi, and Hiroki Hori.

Their publications appear in venues such as UNC Libraries, Tropical Medicine and Health, and Frontiers in Bioscience-Landmark, with multiple works appearing in UNC Libraries.

In addition to journal articles, Kiyono has contributed to book publications, notably with Academic Press. One such book is titled Mucosal vaccines: innovation for preventing infectious diseases, published in 2020.

Best Publications

  • The mucosal immune system : from fundamental concepts to vaccine development

    Jerry R. McGhee;Jiri Mestecky;Mark T. Dertzbaugh;John H. Eldridge

  • Detection of individual mouse splenic T cells producing IFN-γ and IL-5 using the enzyme-linked immunospot (ELISPOT) assay

    Takashi Taguchi;Jerry R. McGhee;Robert L. Coffman;Kenneth W. Beagley

  • NALT- versus PEYER'S-patch-mediated mucosal immunity

    Hiroshi Kiyono;Satoshi Fukuyama

  • Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5

    Satoshi Uematsu;Kosuke Fujimoto;Myoung Ho Jang;Bo Gie Yang

  • Innate Lymphoid Cells Promote Anatomical Containment of Lymphoid-Resident Commensal Bacteria

    Gregory F. Sonnenberg;Laurel A. Monticelli;Theresa Alenghat;Thomas C. Fung

  • Uptake through glycoprotein 2 of FimH(+) bacteria by M cells initiates mucosal immune response.

    Koji Hase;Kazuya Kawano;Tomonori Nochi;Gemilson Soares Pontes

  • Helper T cell subsets for immunoglobulin A responses: oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa associated tissues.

    J Xu-Amano;H Kiyono;R J Jackson;H F Staats

  • Innate lymphoid cells regulate intestinal epithelial cell glycosylation

    Yoshiyuki Goto;Takashi Obata;Jun Kunisawa;Shintaro Sato

  • Nanogel antigenic protein-delivery system for adjuvant-free intranasal vaccines

    Tomonori Nochi;Yoshikazu Yuki;Haruko Takahashi;Shin Ichi Sawada

  • Interleukins and IgA synthesis. Human and murine interleukin 6 induce high rate IgA secretion in IgA-committed B cells.

    K W Beagley;J H Eldridge;F Lee;H Kiyono

  • Identification of Multiple Isolated Lymphoid Follicles on the Antimesenteric Wall of the Mouse Small Intestine

    Hiromasa Hamada;Takachika Hiroi;Yasuhiro Nishiyama;Yasuhiro Nishiyama;Hidemi Takahashi

  • Intestinal villous M cells: An antigen entry site in the mucosal epithelium

    Myoung Ho Jang;Mi Na Kweon;Mi Na Kweon;Mi Na Kweon;Koichi Iwatani;Masafumi Yamamoto;Masafumi Yamamoto;Masafumi Yamamoto

  • CCR7 is critically important for migration of dendritic cells in intestinal lamina propria to mesenteric lymph nodes.

    Myoung Ho Jang;Nagako Sougawa;Toshiyuki Tanaka;Takako Hirata

  • Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4.

    M Marinaro;H F Staats;T Hiroi;R J Jackson

  • Terminology: nomenclature of mucosa-associated lymphoid tissue

    P Brandtzaeg;H Kiyono;R Pabst;M W Russell

  • A nontoxic mutant of cholera toxin elicits Th2-type responses for enhanced mucosal immunity

    Shingo Yamamoto;Hiroshi Kiyono;Masafumi Yamamoto;Koichi Imaoka

  • Rice-based mucosal vaccine as a global strategy for cold-chain- and needle-free vaccination

    Tomonori Nochi;Hidenori Takagi;Yoshikazu Yuki;Lijun Yang

  • Probiotic Bifidobacterium breve Induces IL-10-Producing Tr1 Cells in the Colon

    Seong Gyu Jeon;Hisako Kayama;Yoshiyasu Ueda;Takuya Takahashi

  • Polyunsaturated fatty acid saturation by gut lactic acid bacteria affecting host lipid composition

    Shigenobu Kishino;Michiki Takeuchi;Si Bum Park;Akiko Hirata

  • Regulation of IgA synthesis and immune response by T cells and interleukins.

    Jerry R. McGhee;Jiri Mestecky;Charles O. Elson;Hiroshi Kiyono

  • Regulation of mucosal and systemic antibody responses by T helper cell subsets, macrophages, and derived cytokines following oral immunization with live recombinant Salmonella.

    J L VanCott;H F Staats;D W Pascual;M Roberts

Frequent Co-Authors

Jerry R. McGhee
Jerry R. McGhee University of Alabama at Birmingham
Kohtaro Fujihashi
Kohtaro Fujihashi University of Alabama at Birmingham
Jun Kunisawa
Jun Kunisawa National Institutes of Biomedical Innovation, Health and Nutrition
Yoshikazu Yuki
Yoshikazu Yuki University of Tokyo
Tomonori Nochi
Tomonori Nochi Tohoku University
Ichiro Takahashi
Ichiro Takahashi Hiroshima University
Kenneth W. Beagley
Kenneth W. Beagley Queensland University of Technology
Shintaro Sato
Shintaro Sato Osaka University
Suzanne M. Michalek
Suzanne M. Michalek University of Alabama at Birmingham
John H. Eldridge
John H. Eldridge University of Alabama at Birmingham

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