World's Best Scientists 2026 revealed!
Kazunari Akiyoshi

Kazunari Akiyoshi

D-Index & Metrics

Materials Science

D-Index
71
Citations
17173
World Ranking
4267
National Ranking
192

Chemistry

D-Index
73
Citations
18480
World Ranking
4978
National Ranking
288

Overview

Kazunari Akiyoshi is affiliated with Kyoto University in Japan and has a significant publication record in the field of Biochemistry, Genetics and Molecular Biology. Their research spans several subfields including Molecular Biology, Immunology, Biomedical Engineering, Biomaterials, and Organic Chemistry.

The scientist's work addresses multiple main topics, highlighted by the following areas:

  • RNA Interference and Gene Delivery
  • Extracellular vesicles in disease
  • Immunotherapy and Immune Responses
  • Advanced Polymer Synthesis and Characterization
  • Glycosylation and Glycoproteins Research
  • Lipid Membrane Structure and Behavior
  • Hydrogels: synthesis, properties, applications

Kazunari Akiyoshi has published frequently in several journals. The most common venues include:

  • International Journal of Molecular Sciences (6 publications)
  • Bioconjugate Chemistry (4 publications)
  • Vaccine (4 publications)
  • Polymer Journal (4 publications)
  • ACS Applied Bio Materials (3 publications)

They regularly collaborate with several coauthors, including:

  • Yoshihiro Sasaki (43 coauthored works)
  • Shin-ichi Sawada (33 coauthored works)
  • Tomoki Nishimura (16 coauthored works)
  • Asako Shimoda (12 coauthored works)
  • Ryosuke Mizuta (10 coauthored works)

Their notable recent papers include the following:

  • "Distinguishing functional exosomes and other extracellular vesicles as a nucleic acid cargo by the anion-exchange method," 2022, Journal of Extracellular Vesicles
  • "Thermoresponsive Polysaccharide Graft Polymer Vesicles with Tunable Size and Structural Memory," 2020, Journal of the American Chemical Society
  • "New Lipophilic Fluorescent Dyes for Labeling Extracellular Vesicles: Characterization and Monitoring of Cellular Uptake," 2021, Bioconjugate Chemistry
  • "A nanogel-based trivalent PspA nasal vaccine protects macaques from intratracheal challenge with pneumococci," 2021, Vaccine
  • "Assessment of Surface Glycan Diversity on Extracellular Vesicles by Lectin Microarray and Glycoengineering Strategies for Drug Delivery Applications," 2021, Small Methods

Best Publications

  • Self-aggregates of hydrophobized polysaccharides in water formation and characteristics of nanoparticles

    Kazunari Akiyoshi;Shigeru Deguchi;Nobuhiro Moriguchi;Shigehiko Yamaguchi

  • Engineering hybrid exosomes by membrane fusion with liposomes.

    Yuko T. Sato;Kaori Umezaki;Shinichi Sawada;Sada Atsu Mukai

  • Self-assembled hydrogel nanoparticle of cholesterol-bearing pullulan as a carrier of protein drugs: Complexation and stabilization of insulin

    Kazunari Akiyoshi;Seiichi Kobayashi;Shozo Shichibe;Don Mix

  • Nanogel antigenic protein-delivery system for adjuvant-free intranasal vaccines

    Tomonori Nochi;Yoshikazu Yuki;Haruko Takahashi;Shin Ichi Sawada

  • Nanogel engineering for new nanobiomaterials: from chaperoning engineering to biomedical applications.

    Yoshihiro Sasaki;Kazunari Akiyoshi

  • Gene expression within cell-sized lipid vesicles.

    Shin Ichiro M. Nomura;Kanta Tsumoto;Tsutomu Hamada;Kazunari Akiyoshi

  • Mouthguard biosensor with telemetry system for monitoring of saliva glucose: A novel cavitas sensor.

    Takahiro Arakawa;Yusuke Kuroki;Hiroki Nitta;Prem Chouhan

  • Control of nanobiointerfaces generated from well-defined biomimetic polymer brushes for protein and cell manipulations.

    Ryoko Iwata;Piyawan Suk-In;Vipavee P. Hoven;Atsushi Takahara

  • Soft contact lens biosensor for in situ monitoring of tear glucose as non-invasive blood sugar assessment.

    Ming Xing Chu;Kumiko Miyajima;Daishi Takahashi;Takahiro Arakawa

  • Microscopic structure and thermoresponsiveness of a hydrogel nanoparticle by self-assembly of a hydrophobized polysaccharide

    Kazunari Akiyoshi;Shigeru Deguchi;Hitoshi Tajima;Takehiro Nishikawa

  • Nanogel-quantum dot hybrid nanoparticles for live cell imaging

    Urara Hasegawa;Shin Ichiro M. Nomura;Sunil C. Kaul;Takashi Hirano

  • Macromolecular Complexation between Bovine Serum Albumin and the Self-Assembled Hydrogel Nanoparticle of Hydrophobized Polysaccharides

    Takehiro Nishikawa;Kazunari Akiyoshi;Junzo Sunamoto

  • Protein refolding assisted by self-assembled nanogels as novel artificial molecular chaperone

    Yuta Nomura;Masahiro Ikeda;Nozomi Yamaguchi;Yasuhiro Aoyama

  • Self-assembled cationic nanogels for intracellular protein delivery.

    Hirohito Ayame;Nobuyuki Morimoto;Kazunari Akiyoshi

  • Supramolecular Assembly between Nanoparticles of Hydrophobized Polysaccharide and Soluble Protein Complexation between the Self-Aggregate of Cholesterol-Bearing Pullulan and .alpha.-Chymotrypsin

    Takehiro Nishikawa;Kazunari Akiyoshi;Junzo Sunamoto

  • Molecular chaperone-like activity of hydrogel nanoparticles of hydrophobized pullulan: thermal stabilization with refolding of carbonic anhydrase B.

    Kazunari Akiyoshi;Yoshihiro Sasaki;Junzo Sunamoto

  • Controlled association of amphiphilic polymers in water : Thermosensitive nanoparticles formed by self-assembly of hydrophobically modified pullulans and poly(N-isopropylacrylamides)

    Kazunari Akiyoshi;Eui-Chul Kang;Satoshi Kurumada;Junzo Sunamoto

  • Activated CD8 + T cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells

    Naohiro Seo;Yoshitaka Shirakura;Yoshiro Tahara;Fumiyasu Momose

  • Cholesteryl group- and acryloyl group-bearing pullulan nanogel to deliver BMP2 and FGF18 for bone tissue engineering

    Masako Fujioka-Kobayashi;Masato S. Ota;Asako Shimoda;Asako Shimoda;Ken-ichi Nakahama

  • Nanogel DDS enables sustained release of IL-12 for tumor immunotherapy.

    Takeshi Shimizu;Tsunao Kishida;Urara Hasegawa;Yuji Ueda

Frequent Co-Authors

Yasuhiko Iwasaki
Yasuhiko Iwasaki Kansai University
Hiroshi Kiyono
Hiroshi Kiyono University of Tokyo
Hiroshi Shiku
Hiroshi Shiku Mie University
Yoshikazu Yuki
Yoshikazu Yuki University of Tokyo
Ikuo Morita
Ikuo Morita Ochanomizu University
Tomonori Nochi
Tomonori Nochi Tohoku University
Masaki Noda
Masaki Noda Tokyo Medical and Dental University
Kazuhiko Ishihara
Kazuhiko Ishihara University of Tokyo
Hideo Tsukada
Hideo Tsukada Hamamatsu Photonics (Japan)
Ei-ichi Negishi
Ei-ichi Negishi Purdue University West Lafayette

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