D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 57 Citations 11,776 280 World Ranking 9357 National Ranking 689

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

Kazuhiro Aoki mainly investigates Cell biology, Osteoclast, Bone resorption, MAPK/ERK pathway and Kinase. The Cell biology study combines topics in areas such as Endocrinology, Neurite, Transcription factor, Ectopic expression and Internal medicine. Kazuhiro Aoki combines subjects such as Haematopoiesis and RANKL with his study of Osteoclast.

His biological study spans a wide range of topics, including Multinucleate, Cancer research, Signal transduction, Proto-oncogene tyrosine-protein kinase Src and Resorption. His MAPK/ERK pathway research is multidisciplinary, relying on both Cell, Cell signaling and Cell growth. Kazuhiro Aoki studied Kinase and Extracellular that intersect with Optogenetics, Contraction, Wound healing and Myosin light-chain kinase.

His most cited work include:

  • The afterglow of GRB 050709 and the nature of the short-hard γ-ray bursts (461 citations)
  • Selective inhibition of NF-|[kappa]|B blocks osteoclastogenesis and prevents inflammatory bone destruction in vivo (425 citations)
  • Development of an optimized backbone of FRET biosensors for kinases and GTPases (384 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Cell biology, Internal medicine, Endocrinology, Bone resorption and Osteoclast. Kazuhiro Aoki has researched Cell biology in several fields, including Cell and Förster resonance energy transfer. His research in Endocrinology intersects with topics in Cortical bone and Dental alveolus.

His Bone resorption study combines topics from a wide range of disciplines, such as Bone density, Bone remodeling and Peptide. In Osteoclast, Kazuhiro Aoki works on issues like RANKL, which are connected to Osteoblast, Cancer research and NF-κB. His MAPK/ERK pathway research also works with subjects such as

  • Extracellular which intersects with area such as Contraction and Optogenetics,
  • Intracellular that connect with fields like Cell signaling.

He most often published in these fields:

  • Cell biology (49.65%)
  • Internal medicine (17.61%)
  • Endocrinology (16.90%)

What were the highlights of his more recent work (between 2017-2021)?

  • Cell biology (49.65%)
  • Biophysics (12.68%)
  • Intracellular (10.21%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Cell biology, Biophysics, Intracellular, Kinase and Cell. He interconnects Optogenetics, Cell growth and Förster resonance energy transfer in the investigation of issues within Cell biology. The concepts of his Intracellular study are interwoven with issues in Extracellular and MAPK/ERK pathway.

His biological study deals with issues like Contraction, which deal with fields such as Mechanotransduction and Epidermal growth factor receptor. The Kinase study combines topics in areas such as Crosstalk, Programmed cell death and Chromosomal translocation. His Osteopetrosis research incorporates elements of Osteoclast, Bone resorption and RANKL.

Between 2017 and 2021, his most popular works were:

  • Coupling of bone resorption and formation by RANKL reverse signalling (157 citations)
  • ERK-Mediated Mechanochemical Waves Direct Collective Cell Polarization. (23 citations)
  • ERK-Mediated Mechanochemical Waves Direct Collective Cell Polarization. (23 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

Kazuhiro Aoki spends much of his time researching Cell biology, Kinase, Cell, Extracellular and Signal transduction. The various areas that Kazuhiro Aoki examines in his Cell biology study include RUNX2, Osteoblast and Activator. His study in Kinase is interdisciplinary in nature, drawing from both Live cell imaging, Intracellular signal transduction, Blot and Förster resonance energy transfer.

Kazuhiro Aoki combines subjects such as Cell growth and MAPK/ERK pathway with his study of Extracellular. His Signal transduction research is multidisciplinary, incorporating perspectives in Protein subcellular localization prediction and Cytoplasm. His Resorption research includes elements of Osteoclast, Bone resorption and RANKL.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The afterglow of GRB 050709 and the nature of the short-hard γ-ray bursts

Derek B Fox;Derek B Fox;Dale A Frail;Paul Antony Price;Shrinivas R Kulkarni.
Nature (2005)

707 Citations

Development of an optimized backbone of FRET biosensors for kinases and GTPases

Naoki Komatsu;Kazuhiro Aoki;Masashi Yamada;Hiroko Yukinaga.
Molecular Biology of the Cell (2011)

589 Citations

Selective inhibition of NF-|[kappa]|B blocks osteoclastogenesis and prevents inflammatory bone destruction in vivo

Eijiro Jimi;Eijiro Jimi;Kazuhiro Aoki;Hiroaki Saito;Fulvio D'Acquisto.
Nature Medicine (2004)

582 Citations

Cathepsin K-Dependent Toll-Like Receptor 9 Signaling Revealed in Experimental Arthritis

Masataka Asagiri;Toshitake Hirai;Toshihiro Kunigami;Shunya Kamano;Shunya Kamano.
Science (2008)

407 Citations

Dynamics of the Ras/ERK MAPK Cascade as Monitored by Fluorescent Probes

Aki Fujioka;Kenta Terai;Reina E. Itoh;Kazuhiro Aoki.
Journal of Biological Chemistry (2006)

396 Citations

Overexpression of DeltaFosB transcription factor(s) increases bone formation and inhibits adipogenesis.

G Sabatakos;N A Sims;J Chen;K Aoki.
Nature Medicine (2000)

387 Citations

Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2

Toshihiko Toyofuku;Hong Zhang;Atsushi Kumanogoh;Noriko Takegahara.
Genes & Development (2004)

383 Citations

Regulation of osteoclast differentiation and function by the CaMK-CREB pathway.

Kojiro Sato;Ayako Suematsu;Tomoki Nakashima;Sayaka Takemoto-Kimura.
Nature Medicine (2006)

341 Citations

I[kgr]B[zgr] regulates TH17 development by cooperating with ROR nuclear receptors

Kazuo Okamoto;Yoshiko Iwai;Masatsugu Oh-hora;Masahiro Yamamoto.
Nature (2010)

330 Citations

Coupling of bone resorption and formation by RANKL reverse signalling

Yuki Ikebuchi;Shigeki Aoki;Masashi Honma;Madoka Hayashi.
Nature (2018)

300 Citations

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