Thomas Litman mainly focuses on Molecular biology, ATP-binding cassette transporter, Biochemistry, Rhodamine 123 and Abcg2. His Molecular biology research includes elements of Cell culture and Complementary DNA, Expressed sequence tag, cDNA library, Peptide sequence. His ATP-binding cassette transporter study integrates concerns from other disciplines, such as P-glycoprotein, Antibody, Transitional epithelium and Pathology.
His study in the fields of ATPase, Gut flora and Gene expression under the domain of Biochemistry overlaps with other disciplines such as CCL3. Thomas Litman has included themes like Endocrinology, Chemosensitizer, Efflux, Internal medicine and Chemosensitizing agent in his Rhodamine 123 study. Within one scientific family, Thomas Litman focuses on topics pertaining to Multiple drug resistance under Abcg2, and may sometimes address concerns connected to Irinotecan, Camptothecin and Glucuronidation.
Thomas Litman mainly investigates microRNA, Cancer research, Biochemistry, Molecular biology and Immunology. Thomas Litman interconnects Cancer, Breast cancer, Bioinformatics, Gene expression profiling and Computational biology in the investigation of issues within microRNA. His Cancer research research also works with subjects such as
Thomas Litman combines topics linked to Biophysics with his work on Biochemistry. The study incorporates disciplines such as Cell culture, Efflux, Rhodamine 123 and Western blot in addition to Molecular biology. His research in ATP-binding cassette transporter intersects with topics in Multiple drug resistance and Drug resistance.
The scientist’s investigation covers issues in Cancer research, Mycosis fungoides, Cutaneous T-cell lymphoma, microRNA and Gene. His studies deal with areas such as MHC class I, Estrogen receptor, STAT5, Lymphoma and Antibody as well as Cancer research. His Mycosis fungoides research is multidisciplinary, relying on both Downregulation and upregulation, Transfection and Multicenter study.
The Downregulation and upregulation study which covers Cell that intersects with Immunology and Atopic dermatitis. His research investigates the connection between microRNA and topics such as Epigenetics that intersect with issues in Tumor microenvironment and Disease. His research on Gene frequently links to adjacent areas such as Computational biology.
His primary scientific interests are in Cancer research, Psoriasis, Targeted therapy, Lymphoma and Atopic dermatitis. His Cancer research research is multidisciplinary, incorporating elements of Gene knockdown, Oncogene, microRNA, STAT5 and Antibody. Thomas Litman integrates microRNA and MCF-7 in his research.
His work on Psoriasis Area and Severity Index as part of general Psoriasis study is frequently connected to Secukinumab, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. His Targeted therapy research incorporates themes from Tumor microenvironment, Mycosis fungoides and Disease. His Atopic dermatitis study combines topics from a wide range of disciplines, such as Precision medicine, Personalized medicine, Bioinformatics and Inflammatory pathways.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes.
Keisuke Miyake;Lyn Mickley;Thomas Litman;Zhirong Zhan.
Cancer Research (1999)
From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance.
T. Litman;T. E. Druley;W. D. Stein;S. E. Bates.
Cellular and Molecular Life Sciences (2001)
The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2)
Thomas Litman;Mariafiorella Brangi;Eric Hudson;Patricia Fetsch.
Journal of Cell Science (2000)
Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells
Yasumasa Honjo;Christine A. Hrycyna;Qing-Wu Yan;Wilma Y. Medina-Pérez.
Cancer Research (2001)
Overexpression of the ATP-binding Cassette Half-Transporter, ABCG2 (MXR/BCRP/ABCP1), in Flavopiridol-resistant Human Breast Cancer Cells
Robert W. Robey;Wilma Y. Medina-Pérez;Kenryu Nishiyama;Tyler Lahusen.
Clinical Cancer Research (2001)
Functional Characterization of the Human Multidrug Transporter, ABCG2, Expressed in Insect Cells
Csilla Özvegy;Thomas Litman;Gergely Szakács;Zoltán Nagy.
Biochemical and Biophysical Research Communications (2001)
Reversal of resistance by GF120918 in cell lines expressing the ABC half-transporter, MXR
Michiel de Bruin;Keisuke Miyake;Thomas Litman;Robert Robey.
Cancer Letters (1999)
Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells.
Mariafiorella Brangi;Thomas Litman;Marco Ciotti;Kenryu Nishiyama.
Cancer Research (1999)
A functional assay for detection of the mitoxantrone resistance protein, MXR (ABCG2).
Robert W Robey;Yasumasa Honjo;Anne van de Laar;Keisuke Miyake.
Biochimica et Biophysica Acta (2001)
Diagnostic and prognostic signatures from the small non-coding RNA transcriptome in prostate cancer
E S Martens-Uzunova;S E Jalava;N F Dits;G J L H van Leenders.
Oncogene (2012)
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