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Biology and Biochemistry

D-Index
61
Citations
12317
World Ranking
11432
National Ranking
128

Overview

Henrik J. Ditzel is affiliated with the University of Southern Denmark in Denmark and has an extensive publication record in the fields of medicine and biochemistry, genetics, and molecular biology. Their research spans multiple subfields including molecular biology, oncology, cancer research, pulmonary and respiratory medicine, and immunology.

Their recent publications demonstrate a focus on cancer biology and immunotherapy, with topics related to breast cancer, cancer molecular pathways, and immune responses. Recent papers include:

  • IFI16-dependent STING signaling is a crucial regulator of anti-HER2 immune response in HER2+ breast cancer, 2022, Proceedings of the National Academy of Sciences
  • HMGA2 as a Critical Regulator in Cancer Development, 2021, Genes
  • Antibody and T cell immune responses following mRNA COVID-19 vaccination in patients with cancer, 2021, Cancer Cell
  • Hypoxia induces HIF1α-dependent epigenetic vulnerability in triple negative breast cancer to confer immune effector dysfunction and resistance to anti-PD-1 immunotherapy, 2022, Nature Communications
  • AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells, 2020, Journal of Thoracic Oncology

Their collaborations include frequent coauthors such as Mikkel G. Terp, Morten F. Gjerstorff, Sidse Ehmsen, Carla L. Alves, and Martina Tuttolomondo, reflecting ongoing teamwork in cancer and molecular biology research.

Henrik J. Ditzel's work is published frequently in journals including:

  • Journal of Geriatric Oncology
  • Cancer Cell
  • Nature Communications
  • Cancers
  • Frontiers in Oncology

Their main research topics cover:

  • Advanced Breast Cancer Therapies
  • Cancer-related Molecular Pathways
  • Frailty in Older Adults
  • Nutrition and Health in Aging
  • Epigenetics and DNA Methylation
  • RNA Interference and Gene Delivery
  • Cancer Genomics and Diagnostics

Henrik J. Ditzel has contributed mainly to the advancement of knowledge in oncology and molecular biology, with particular emphasis on cancer immunology, therapeutic targets, and the molecular mechanisms underlying cancer development and therapy resistance. Their research incorporates immunotherapy, epigenetic regulation, and the interactions between tumor biology and systemic aging processes.

Best Publications

  • CYP2D6 Genotype and Tamoxifen Response in Postmenopausal Women with Endocrine-Responsive Breast Cancer: The Breast International Group 1-98 Trial

    Meredith M. Regan;Brian Leyland-Jones;Mark Bouzyk;Olivia Pagani

  • Autoantibodies to GPI in rheumatoid arthritis: linkage between an animal model and human disease

    Monica Schaller;Dennis R. Burton;Henrik J. Ditzel

  • Oncogenic cancer/testis antigens: prime candidates for immunotherapy

    Morten F. Gjerstorff;Mads H. Andersen;Henrik J. Ditzel

  • Stromal CD8+ T Cell Density - A Promising Supplement to TNM staging in Non-Small Cell Lung Cancer

    Tom Donnem;Sigurd M Hald;Erna-Elise Paulsen;Elin Richardsen

  • Visualization of Myelin Basic Protein (Mbp) T Cell Epitopes in Multiple Sclerosis Lesions Using a Monoclonal Antibody Specific for the Human Histocompatibility Leukocyte Antigen (Hla)-Dr2–Mbp 85–99 Complex

    Michelle Krogsgaard;Kai W. Wucherpfennig;Barbara Canella;Bjarke E. Hansen

  • Neutralization of Human Immunodeficiency Virus Type 1 by Antibody to gp120 Is Determined Primarily by Occupancy of Sites on the Virion Irrespective of Epitope Specificity

    Paul W. H. I. Parren;Isabelle Mondor;Denise Naniche;Henrik J. Ditzel

  • Human autoantibody recognition of DNA.

    Shana M. Barbas;Henrik J. Ditzel;Eeva M. Salonen;Wei Ping Yang

  • Novel circulating microRNA signature as a potential non-invasive multi-marker test in ER-positive early-stage breast cancer: A case control study

    Annette R Kodahl;Annette R Kodahl;Maria Bibi Lyng;Harald Binder;Søren Cold;Søren Cold

  • Co-activation of STAT3 and YES-Associated Protein 1 (YAP1) Pathway in EGFR-Mutant NSCLC

    Imane Chaib;Niki Karachaliou;Sara Pilotto;Jordi Codony Servat

  • The tumor-infiltrating B cell response in medullary breast cancer is oligoclonal and directed against the autoantigen actin exposed on the surface of apoptotic cancer cells.

    Margit H. Hansen;Heidi Nielsen;Henrik J. Ditzel

  • Protection against HIV-1 infection in hu-PBL-SCID mice by passive immunization with a neutralizing human monoclonal antibody against the gp120 CD4-binding site.

    Paul W.h.i. Parren;Henrik J. Ditzel;Richard J. Gulizia;James M. Binley

  • Plasma Membrane Proteomics and Its Application in Clinical Cancer Biomarker Discovery

    Rikke Leth-Larsen;Rikke Raaen Lund;Henrik Jørn Ditzel;Henrik Jørn Ditzel

  • IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel.

    Zhen Ning Wee;Siti Maryam J M Yatim;Vera K Kohlbauer;Min Feng

  • The K/BxN mouse: a model of human inflammatory arthritis.

    Henrik J. Ditzel

  • Metastasis-related Plasma Membrane Proteins of Human Breast Cancer Cells Identified by Comparative Quantitative Mass Spectrometry

    Rikke Leth-Larsen;Rikke Lund;Helle V. Hansen;Anne Vibeke Laenkholm

  • Determinants of polyreactivity in a large panel of recombinant human antibodies from HIV-1 infection

    Henrik J. Ditzel;Kunihiko Itoh;Dennis R. Burton

  • Convergent Akt activation drives acquired EGFR inhibitor resistance in lung cancer.

    Kirstine Jacobsen;Jordi Bertran-Alamillo;Miguel Angel Molina;Cristina Teixidó

  • Anti-Human CD73 Monoclonal Antibody Inhibits Metastasis Formation in Human Breast Cancer by Inducing Clustering and Internalization of CD73 Expressed on the Surface of Cancer Cells

    Mikkel G. Terp;Kristina A. Olesen;Eva C. Arnspang;Rikke R. Lund

  • Chromosome 1q21.3 amplification is a trackable biomarker and actionable target for breast cancer recurrence

    Jian Yuan Goh;Min Feng;Wenyu Wang;Gokce Oguz;Gokce Oguz

  • Fyn is an important molecule in cancer pathogenesis and drug resistance.

    Daniel Elias;Henrik J. Ditzel

Frequent Co-Authors

Paul W. H. I. Parren
Paul W. H. I. Parren Leiden University Medical Center
Dennis R. Burton
Dennis R. Burton Scripps Research Institute
Nils Brünner
Nils Brünner University of Copenhagen
Jan Baumbach
Jan Baumbach Universität Hamburg
James M. Binley
James M. Binley Aaron Diamond AIDS Research Center
Ole Nørregaard Jensen
Ole Nørregaard Jensen University of Southern Denmark
Carlos F. Barbas
Carlos F. Barbas Scripps Research Institute
Martin R. Larsen
Martin R. Larsen University of Southern Denmark
Jens C. Jensenius
Jens C. Jensenius Aarhus University
Lars Bolund
Lars Bolund Aarhus University

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