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Medicine

D-Index
88
Citations
26963
World Ranking
13215
National Ranking
145

Overview

Nils Brünner is affiliated with the University of Copenhagen in Denmark. Their research primarily spans the fields of Medicine as well as Biochemistry, Genetics and Molecular Biology. Within these broader fields, their work focuses significantly on Oncology, Molecular Biology, Cancer Research, Pathology and Forensic Medicine, and Pulmonary and Respiratory Medicine.

Their main research topics include Drug Transport and Resistance Mechanisms, Colorectal Cancer Treatments and Studies, Cancer Therapeutics and Mechanisms, Genetic Factors in Colorectal Cancer, Cancer Treatment and Pharmacology, Colorectal Cancer Screening and Detection, and Circular RNAs in diseases.

Frequent publication venues for their work include Cancer Research, Gastroenterology, International Journal of Molecular Sciences, Frontiers in Oncology, and Cells.

Among their recent papers are:

  • Proteomic Profiling of Colorectal Adenomas Identifies a Predictive Risk Signature for Development of Metachronous Advanced Colorectal Neoplasia, 2023, Gastroenterology
  • A Comprehensive RNA Study to Identify circRNA and miRNA Biomarkers for Docetaxel Resistance in Breast Cancer, 2021, Frontiers in Oncology
  • The Pyrazolo[3,4-d]pyrimidine Derivative, SCO-201, Reverses Multidrug Resistance Mediated by ABCG2/BCRP, 2020, Cells
  • ABCG2 Protein Levels and Association to Response to First-Line Irinotecan-Based Therapy for Patients with Metastatic Colorectal Cancer, 2020, International Journal of Molecular Sciences
  • New use for old drugs: Epirubicin in colorectal cancer, 2021, Acta Oncologica

Nils Brünner frequently collaborates with colleagues including Jan Stenvang, Peter Michael Vestlev, Sophie E. B. Ambjørner, Lasse Saaby, and Birger Brodin. These collaborations have contributed to publications across their main fields of study.

Best Publications

  • Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer

    Jun Yu;Qiang Feng;Sunny Hei Wong;Dongya Zhang

  • Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization

    Khalid Bajou;Agnès Noël;R. D. Gerard;Véronique Masson

  • Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in 8377 breast cancer patients.

    Maxime P. Look;Wim L. J. van Putten;Michael J. Duffy;Nadia Harbeck

  • Association of increased basement membrane invasiveness with absence of estrogen receptor and expression of vimentin in human breast cancer cell lines.

    Erik W. Thompson;Soonmyoung Paik;Nils Brünner;Connie L. Sommers

  • The Urokinase System of Plasminogen Activation and Prognosis in 2780 Breast Cancer Patients

    J. A. Foekens;H. A. Peters;M. P. Look;H. Portengen

  • National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines for Use of Tumor Markers in Testicular, Prostate, Colorectal, Breast, and Ovarian Cancers

    Catharine M. Sturgeon;Michael J. Duffy;Ulf Håkan Stenman;Hans Lilja

  • High levels of urokinase-type plasminogen activator and its inhibitor PAI-1 in cytosolic extracts of breast carcinomas are associated with poor prognosis.

    Jan Grøndahl-Hansen;Ib Jarle Christensen;Christian Rosenquist;Nils Brünner

  • Prognostic Impact of Urokinase, Urokinase Receptor, and Type 1 Plasminogen Activator Inhibitor in Squamous and Large Cell Lung Cancer Tissue

    Helle Pedersen;Nils Brünner;Dorthe Francis;Kell Østerlind

  • The Plasminogen Activator Inhibitor PAI-1 Controls In Vivo Tumor Vascularization by Interaction with Proteases, Not Vitronectin: Implications for Antiangiogenic Strategies

    Khalid Bajou;Véronique Masson;Robert D. Gerard;Petra M. Schmitt

  • Plasma Urokinase Receptor Levels in Patients With Colorectal Cancer: Relationship to Prognosis

    Ross W. Stephens;Hans Jørgen Nielsen;Ib J. Christensen;Ole Thorlacius-Ussing

  • The urokinase receptor. Protein structure and role in plasminogen activation and cancer invasion

    K. Danø;N. Behrendt;N. Brunner;V. Ellis

  • High levels of microRNA-21 in the stroma of colorectal cancers predict short disease-free survival in stage II colon cancer patients

    Boye Schnack Nielsen;Stine Jørgensen;Jacob Ulrik Fog;Rolf Søkilde

  • Localization of tissue inhibitor of metalloproteinases 1 (TIMP‐1) in human colorectal adenoma and adenocarcinoma

    Mads N. Holten-Andersen;Ulla Hansen;Nils Brünner;Hans Jørgen Nielsen

  • Independent prognostic value of eosinophil and mast cell infiltration in colorectal cancer tissue.

    Hans Jørgen Nielsen;Ulla Hansen;Ib Jarle Christensen;Claus Michael Reimert

  • Receptor for Urokinase Is Present in Tumor-associated Macrophages in Ductal Breast Carcinoma

    C Pyke;N Graem;E Ralfkiaer;E Rønne

  • Cysteine Proteinase Inhibitors Stefin A, Stefin B, and Cystatin C in Sera from Patients with Colorectal Cancer: Relation to Prognosis

    Janko Kos;Marta Krašovec;Nina Cimerman;Hans Jørgen Nielsen

  • MCF7/LCC9: an antiestrogen-resistant MCF-7 variant in which acquired resistance to the steroidal antiestrogen ICI 182,780 confers an early cross-resistance to the nonsteroidal antiestrogen tamoxifen.

    Nils Brünner;Nils Brünner;Birgitte Boysen;Stana Jirus;Todd C. Skaar

  • Prognostic significance of the receptor for urokinase plasminogen activator in breast cancer.

    J. Grøndahl-Hansen;H. A. Peters;W. L. J. Van Putten;M. P. Look

  • The Level of Urokinase-type Plasminogen Activator Receptor Is Increased in Serum of Ovarian Cancer Patients

    Cornelis F. M. Sier;Ross Stephens;Jozef Bizik;Andrea Mariani

  • Urokinase and Plasminogen Activator Inhibitor Type 1 in Pulmonary Adenocarcinoma

    Helle Pedersen;Jan Grøndahl-Hansen;Dorte Francis;Kell Østerlind

Frequent Co-Authors

Ib Jarle Christensen
Ib Jarle Christensen University of Copenhagen
Keld Danø
Keld Danø Copenhagen University Hospital
Gunilla Høyer-Hansen
Gunilla Høyer-Hansen University of Copenhagen
Robert Clarke
Robert Clarke University of Oxford
John A. Foekens
John A. Foekens Erasmus University Rotterdam
Manfred Schmitt
Manfred Schmitt Technical University of Munich
Henrik J. Ditzel
Henrik J. Ditzel University of Southern Denmark
Erik W. Thompson
Erik W. Thompson Queensland University of Technology
Søren Laurberg
Søren Laurberg Aarhus University Hospital
Bengt Glimelius
Bengt Glimelius Uppsala University

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