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Gunilla Høyer-Hansen

Gunilla Høyer-Hansen

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
9752
World Ranking
12806
National Ranking
137

Overview

Gunilla Høyer-Hansen is affiliated with the University of Copenhagen in Denmark. Their research primarily focuses on medicine with significant contributions to biochemistry, genetics, and molecular biology. The scientist's work spans several specialized subfields including surgery, cancer research, oncology, and molecular biology.

Their publications frequently appear in venues such as Cancers, Journal of Clinical Oncology, and the SSRN Electronic Journal. Their recent papers include:

  • Circulating Forms of Urokinase-Type Plasminogen Activator Receptor in Plasma Can Predict Recurrence and Survival in Patients with Urothelial Carcinoma of the Bladder, 2021, Cancers
  • Soluble urokinase-type plasminogen activator receptor, suPAR, as a prognostic biomarker in advanced pancreatic cancer., 2023, Journal of Clinical Oncology
  • Elevated Levels of Cleaved Soluble Forms of Urokinase-Type Plasminogen Activator Receptor are Associated with Poor Survival in Advanced Pancreatic Cancer, 2025, SSRN Electronic Journal

The main topics addressed in their research include protease and inhibitor mechanisms, bladder and urothelial cancer treatments, urinary and genital oncology studies, esophageal cancer research and treatment, peptidase inhibition and analysis, and extracellular vesicles in disease.

  • Protease and Inhibitor Mechanisms
  • Bladder and Urothelial Cancer Treatments
  • Urinary and Genital Oncology Studies
  • Esophageal Cancer Research and Treatment
  • Peptidase Inhibition and Analysis
  • Extracellular vesicles in disease

Frequent collaborators in their research include Ib Jarle Christensen, Rikke Løvendahl Eefsen, Astrid Z. Johansen, Inna M. Chen, and Per Pfeiffer, indicating a network of coauthors with multiple joint publications.

  • Ib Jarle Christensen
  • Rikke Løvendahl Eefsen
  • Astrid Z. Johansen
  • Inna M. Chen
  • Per Pfeiffer

Best Publications

  • Plasminogen activation and cancer

    Keld Danø;Niels Behrendt;Gunilla Høyer-Hansen;Morten Johnsen

  • Urokinase plasminogen activator cleaves its cell surface receptor releasing the ligand-binding domain.

    G Høyer-Hansen;E Rønne;H Solberg;N Behrendt

  • Receptor for Urokinase Is Present in Tumor-associated Macrophages in Ductal Breast Carcinoma

    C Pyke;N Graem;E Ralfkiaer;E Rønne

  • Internalization of the urokinase-plasminogen activator inhibitor type-1 complex is mediated by the urokinase receptor.

    D. Olson;J. Pöllänen;G. Høyer-Hansen;E. Rønne

  • The Multifaceted Role of the Microenvironment in Liver Metastasis: Biology and Clinical Implications

    Gert G. Van den Eynden;Ali W. Majeed;Martin Illemann;Peter B. Vermeulen

  • Cell-induced potentiation of the plasminogen activation system is abolished by a monoclonal antibody that recognizes the NH2-terminal domain of the urokinase receptor.

    Ebbe Rønne;Niels Behrendt;Vincent Ellis;Michael Ploug

  • ELISA determination of soluble urokinase receptor in blood from healthy donors and cancer patients

    Ross W. Stephens;Anders N. Pedersen;Hans Jørgen Nielsen;Maria J. A. G. Hamers

  • Quantitation of TIMP-1 in plasma of healthy blood donors and patients with advanced cancer.

    M N Holten-Andersen;G Murphy;H J Nielsen;A N Pedersen;A N Pedersen

  • The receptor for urokinase-type plasminogen activator and urokinase is translocated from two distinct intracellular compartments to the plasma membrane on stimulation of human neutrophils

    T Plesner;M Ploug;V Ellis;E Ronne

  • Chlorophyll-proteins of the photosystem II antenna system.

    R Bassi;G Høyer-Hansen;R Barbato;G M Giacometti

  • The intact urokinase receptor is required for efficient vitronectin binding: receptor cleavage prevents ligand interaction

    Gunilla Høyer-Hansen;Niels Behrendt;Michael Ploug;Keld Danø

  • Localization of the disulfide bonds in the NH2-terminal domain of the cellular receptor for human urokinase-type plasminogen activator. A domain structure belonging to a novel superfamily of glycolipid-anchored membrane proteins.

    M Ploug;M Kjalke;E Rønne;U Weidle

  • Urokinase-type plasminogen activation in three human breast cancer cell lines correlates with their in vitro invasiveness.

    Claus Holst-Hansen;Bente Johannessen;Gunilla Hoyer-Hansen;John Romer

  • A ligand-free, soluble urokinase receptor is present in the ascitic fluid from patients with ovarian cancer.

    N Pedersen;M Schmitt;E Rønne;M I Nicoletti

  • The receptor for urokinase-type plasminogen activator is deficient on peripheral blood leukocytes in patients with paroxysmal nocturnal hemoglobinuria.

    Michael Ploug;Torben Plesner;Ebbe RØnne;Vincent Ellis

  • Cell‐Surface Acceleration of Urokinase‐Catalyzed Receptor Cleavage

    Gunilla Høyer‐Hansen;Michael Ploug;Niels Behrendt;Ebbe Rønne

  • Prognostic Significance of Soluble Urokinase Plasminogen Activator Receptor in Serum and Cytosol of Tumor Tissue from Patients with Primary Breast Cancer

    Rikke Riisbro;Ib J. Christensen;Timo Piironen;Michael Greenall

  • The murine receptor for urokinase-type plasminogen activator is primarily expressed in tissues actively undergoing remodeling.

    Helene Solberg;Michael Ploug;Gunilla Høyer–Hansen;Boye S. Nielsen

  • Extracellular Collagenases and the Endocytic Receptor, Urokinase Plasminogen Activator Receptor-associated Protein/Endo180, Cooperate in Fibroblast-mediated Collagen Degradation

    Daniel H. Madsen;Lars H. Engelholm;Signe Ingvarsen;Thore Hillig

  • Immunohistochemical detection of the receptor for urokinase plasminogen activator in human colon cancer.

    C Pyke;E Ralfkiaer;E Rønne;Gunilla Høyer-Hansen

Frequent Co-Authors

Keld Danø
Keld Danø Copenhagen University Hospital
Ib Jarle Christensen
Ib Jarle Christensen University of Copenhagen
Nils Brünner
Nils Brünner University of Copenhagen
Niels Behrendt
Niels Behrendt Technical University of Denmark
Michael Ploug
Michael Ploug University of Copenhagen
Leif R. Lund
Leif R. Lund University of Copenhagen
Henrik Ullum
Henrik Ullum Statens Serum Institut
Boye Schnack Nielsen
Boye Schnack Nielsen Bioneer (Denmark)
Bente Klarlund Pedersen
Bente Klarlund Pedersen University of Copenhagen
Peter B. Vermeulen
Peter B. Vermeulen University of Antwerp

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