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Biology and Biochemistry

D-Index
62
Citations
16484
World Ranking
10651
National Ranking
4629

Overview

Stefano Rivella is affiliated with the Children's Hospital of Philadelphia in the United States. Their research primarily spans the fields of medicine, with significant contributions in biochemistry, genetics, and molecular biology.

The main subfields where Rivella has published extensively include genetics, hematology, molecular biology, physiology, and immunology.

Their work focuses on several key topics within these fields, covering hemoglobinopathies and related disorders, iron metabolism and disorders, erythrocyte function and pathophysiology, virus-based gene therapy research, RNA interference and gene delivery, CRISPR and genetic engineering, and blood groups and transfusion.

Rivella has published multiple papers addressing these areas. Recent publications include:

  • In vivo hematopoietic stem cell modification by mRNA delivery (2023, Science)
  • DNA binding to TLR9 expressed by red blood cells promotes innate immune activation and anemia (2021, Science Translational Medicine)
  • Revisiting the non-transfusion-dependent (NTDT) vs. transfusion-dependent (TDT) thalassemia classification 10 years later (2020, American Journal of Hematology)
  • Correcting β-thalassemia by combined therapies that restrict iron and modulate erythropoietin activity (2020, Blood)
  • TMPRSS6 as a Therapeutic Target for Disorders of Erythropoiesis and Iron Homeostasis (2023, Advances in Therapy)

Their frequent publication venues reflect the focus on hematological and molecular research and include Blood, HemaSphere, American Journal of Hematology, bioRxiv (Cold Spring Harbor Laboratory), and Molecular Therapy.

Rivella frequently collaborates with other researchers in the field. The most common co-authors include Amaliris Guerra, Laura Breda, Carla Casu, Yelena Ginzburg, and Carlo Castruccio Castracani.

Best Publications

  • Identification of erythroferrone as an erythroid regulator of iron metabolism

    Léon Kautz;Grace Jung;Erika V Valore;Stefano Rivella

  • A Red Carpet for Iron Metabolism

    Martina U. Muckenthaler;Stefano Rivella;Matthias W. Hentze;Bruno Galy

  • Identification of a novel X-linked gene responsible for Emery-Dreifuss muscular dystrophy.

    Silvia Bione;Elena Maestrini;Stefano Rivella;Mita Mancini

  • Therapeutic haemoglobin synthesis in β-thalassaemic mice expressing lentivirus-encoded human β-globin

    Chad May;Stefano Rivella;John Callegari;Glenn Heller

  • Reactivation of developmentally silenced globin genes by forced chromatin looping.

    Wulan Deng;Wulan Deng;Jeremy W. Rupon;Ivan Krivega;Laura Breda

  • Ineffective erythropoiesis in β-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin

    Sara Gardenghi;Maria F. Marongiu;Pedro Ramos;Pedro Ramos;Ella Guy

  • Targeting iron metabolism in drug discovery and delivery

    Bart J. Crielaard;Twan Lammers;Stefano Rivella

  • Unexpected expression of α- and β-globin in mesencephalic dopaminergic neurons and glial cells

    Marta Biagioli;Milena Pinto;Daniela Cesselli;Marta Zaninello

  • A novel murine model of Cooley anemia and its rescue by lentiviral-mediated human β-globin gene transfer

    Stefano Rivella;Chad May;Amy Chadburn;Isabelle Rivière

  • Non-transfusion-dependent thalassemias

    Khaled M. Musallam;Stefano Rivella;Elliott Vichinsky;Eliezer A. Rachmilewitz

  • The cHS4 insulator increases the probability of retroviral expression at random chromosomal integration sites.

    Stefano Rivella;John A. Callegari;Chad May;Cui Wen Tan

  • Structure-function analysis of ferroportin defines the binding site and an alternative mechanism of action of hepcidin.

    Sharraya Aschemeyer;Bo Qiao;Deborah Stefanova;Erika V. Valore

  • Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice

    Sara Gardenghi;Pedro Ramos;Pedro Ramos;Maria Franca Marongiu;Luca Melchiori

  • Macrophages support pathological erythropoiesis in polycythemia vera and [beta]-thalassemia

    Pedro L Ramos;Carla Casu;Sara Gardenghi;Laura Breda

  • Reducing TMPRSS6 ameliorates hemochromatosis and β-thalassemia in mice

    Shuling Guo;Carla Casu;Sara Gardenghi;Sheri Booten

  • Recommendations regarding splenectomy in hereditary hemolytic anemias

    Achille Iolascon;Immacolata Andolfo;Wilma Barcellini;Francesco Corcione

  • Successful treatment of murine β-thalassemia intermedia by transfer of the human β-globin gene

    Chad May;Stefano Rivella;Amy Chadburn;Michel Sadelain

  • Iron and Reactive Oxygen Species: Friends or Foes of Cancer Cells?

    Laura M. Bystrom;Monica L. Guzman;Stefano Rivella

  • Ineffective erythropoiesis and thalassemias

    Stefano Rivella

  • β-thalassemia: a model for elucidating the dynamic regulation of ineffective erythropoiesis and iron metabolism.

    Yelena Ginzburg;Stefano Rivella

Frequent Co-Authors

Eliezer A. Rachmilewitz
Eliezer A. Rachmilewitz Wolfson Medical Center
Elizabeta Nemeth
Elizabeta Nemeth University of California, Los Angeles
Michel Sadelain
Michel Sadelain Columbia University
Roberto Gambari
Roberto Gambari University of Ferrara
Daniela Toniolo
Daniela Toniolo Vita-Salute San Raffaele University
Nicoletta Bianchi
Nicoletta Bianchi University of Ferrara
Elena Maestrini
Elena Maestrini University of Bologna
Maria Domenica Cappellini
Maria Domenica Cappellini University of Milan
Antonia Follenzi
Antonia Follenzi University of Eastern Piedmont Amadeo Avogadro
Monica Borgatti
Monica Borgatti University of Ferrara

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