World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
92
Citations
29832
World Ranking
11347
National Ranking
332

Shun Shimohama publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where Shun Shimohama sits on this spectrum.

101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 611 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101 publications 1,796+

This scientist: 509 publications — 59th percentile

59% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

Shun Shimohama D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where Shun Shimohama sits on this spectrum.

70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 400 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70 D-Index 217+

This scientist: 92 D-Index — 45th percentile

45% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Overview

Shun Shimohama is affiliated with Sapporo Medical University in Japan and has contributed extensively to the fields of medicine and neuroscience. Their research spans a variety of topics predominantly centered on neurological disorders and molecular mechanisms underlying neurodegeneration.

The main fields of study for Shimohama include Medicine and Neuroscience, with a specific focus on subfields such as Neurology, Molecular Biology, Cellular and Molecular Neuroscience, Physiology, and Pathology and Forensic Medicine.

Themes central to their research encompass:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Alzheimer's disease research and treatments
  • Nicotinic Acetylcholine Receptors Study
  • Amyotrophic Lateral Sclerosis Research
  • Parkinson's Disease Mechanisms and Treatments
  • Genetic Neurodegenerative Diseases
  • Neurogenetic and Muscular Disorders Research

Shimohama's recent publications include:

  • Efficacy and Safety of Ultrahigh-Dose Methylcobalamin in Early-Stage Amyotrophic Lateral Sclerosis, 2022, JAMA Neurology
  • Clinicopathologic Features of Oculopharyngodistal Myopathy With LRP12 CGG Repeat Expansions Compared With Other Oculopharyngodistal Myopathy Subtypes, 2021, JAMA Neurology
  • Roles of microglia in Alzheimer's disease and impact of new findings on microglial heterogeneity as a target for therapeutic intervention, 2021, Biochemical Pharmacology
  • HLA genotype-clinical phenotype correlations in multiple sclerosis and neuromyelitis optica spectrum disorders based on Japan MS/NMOSD Biobank data, 2021, Scientific Reports
  • Nicotinic Acetylcholine Receptors and Microglia as Therapeutic and Imaging Targets in Alzheimer's Disease, 2022, Molecules

The frequent co-authors collaborating with Shimohama are:

  • Shin Hisahara
  • Kazuyuki Takata
  • Kaneyasu Nishimura
  • Daisuke Yamamoto
  • Koki Harada

Publication venues frequently chosen by Shimohama include:

  • Rinsho Shinkeigaku
  • Internal Medicine
  • JAMA Neurology
  • Scientific Reports
  • Proceedings for Annual Meeting of The Japanese Pharmacological Society

Best Publications

  • Oxidative damage is the earliest event in Alzheimer disease.

    Akihiko Nunomura;George Perry;Gjumrakch Aliev;Keisuke Hirai;Keisuke Hirai

  • Mitochondrial abnormalities in Alzheimer's disease.

    Keisuke Hirai;Gjumrakch Aliev;Akihiko Nunomura;Akihiko Nunomura;Hisashi Fujioka

  • Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study

    James F Howard;Kimiaki Utsugisawa;Michael Benatar;Hiroyuki Murai

  • Activation and Involvement of p38 Mitogen-activated Protein Kinase in Glutamate-induced Apoptosis in Rat Cerebellar Granule Cells *

    Hiroshi Kawasaki;Takaya Morooka;Shun Shimohama;Jun Kimura

  • α7 Nicotinic Receptor Transduces Signals to Phosphatidylinositol 3-Kinase to Block A β-Amyloid-induced Neurotoxicity

    Takeshi Kihara;Shun Shimohama;Hideyuki Sawada;Kazuhiro Honda

  • Nicotinic receptor stimulation protects neurons against beta-amyloid toxicity

    T. Kihara;S. Shimohama;H. Sawada;J. Kimura

  • Microglial activation and amyloid-β clearance induced by exogenous heat-shock proteins

    Jun Ichi Kakimura;Yoshihisa Kitamura;Kazuyuki Takata;Masaaki Umeki

  • Activation of NADPH oxidase in Alzheimer's disease brains.

    Shun Shimohama;Hiroko Tanino;Naoko Kawakami;Naoki Okamura

  • Changes in nicotinic and muscarinic cholinergic receptors in Alzheimer-type dementia.

    Shun Shimohama;Takashi Taniguchi;Motohatsu Fujiwara;Masakuni Kameyama

  • The 4F2hc/LAT1 complex transports L-DOPA across the blood-brain barrier.

    Takashi Kageyama;Masaru Nakamura;Akinori Matsuo;Yasuomi Yamasaki

  • Ribosomal RNA in Alzheimer Disease Is Oxidized by Bound Redox-active Iron

    Kazuhiro Honda;Mark A. Smith;Xiongwei Zhu;Diane Baus

  • Nicotine-induced protection of cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity.

    Akinori Akaike;Yutaka Tamura;Takeharu Yokota;Shun Shimohama

  • Apoptosis in Alzheimer's disease--an update.

    Shun Shimohama

  • ESTRADIOL PROTECTS MESENCEPHALIC DOPAMINERGIC NEURONS FROM OXIDATIVE STRESS-INDUCED NEURONAL DEATH

    Hideyuki Sawada;Masakazu Ibi;Takeshi Kihara;Makoto Urushitani

  • Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation

    Shin Hisahara;Susumu Chiba;Hiroyuki Matsumoto;Masaya Tanno

  • Alteration of proteins regulating apoptosis, Bcl-2, Bcl-x, Bax, Bak, Bad, ICH-1 and CPP32, in Alzheimer's disease

    Yoshihisa Kitamura;Shun Shimohama;Wataru Kamoshima;Takashi Ota

  • Phosphatidylinositol 3‐kinase mediates neuroprotection by estrogen in cultured cortical neurons

    Kazuhiro Honda;Hideyuki Sawada;Takeshi Kihara;Makoto Urushitani

  • Neurodegeneration of mouse nigrostriatal dopaminergic system induced by repeated oral administration of rotenone is prevented by 4-phenylbutyrate, a chemical chaperone.

    Masatoshi Inden;Yoshihisa Kitamura;Hiroki Takeuchi;Takashi Yanagida

  • Trophic effect of β-amyloid precursor protein on cerebral cortical neurons in culture

    Wataru Araki;Nobuya Kitaguchi;Yasuo Tokushima;Kazuhiro Ishii

  • Protective effects of 1α,25-(OH)2D3 against the neurotoxicity of glutamate and reactive oxygen species in mesencephalic culture

    M Ibi;H Sawada;M Nakanishi;T Kume

Frequent Co-Authors

Jun Kimura
Jun Kimura University of Iowa
Akinori Akaike
Akinori Akaike Kyoto University
Takeshi Kihara
Takeshi Kihara Kyoto University
Takashi Taniguchi
Takashi Taniguchi National Institute for Materials Science
Ryosuke Takahashi
Ryosuke Takahashi Kyoto University
George Perry
George Perry The University of Texas at San Antonio
Masakuni Kameyama
Masakuni Kameyama Kyoto University
Mark A. Smith
Mark A. Smith Case Western Reserve University
Hiroshi Shibasaki
Hiroshi Shibasaki Kyoto University
Shuji Kaneko
Shuji Kaneko Kyoto University

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