World's Best Scientists 2026 revealed!
Akinori Akaike

Akinori Akaike

D-Index & Metrics

Medicine

D-Index
85
Citations
21477
World Ranking
14780
National Ranking
451

Akinori Akaike publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where Akinori Akaike sits on this spectrum.

101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 611 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101 publications 1,796+

This scientist: 410 publications — 41st percentile

41% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

Akinori Akaike D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where Akinori Akaike sits on this spectrum.

70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 400 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70 D-Index 217+

This scientist: 85 D-Index — 29th percentile

29% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Overview

Akinori Akaike is affiliated with Kyoto University in Japan. Their research work spans fields including Medicine and Biochemistry, Genetics, and Molecular Biology with a focus on several key subfields such as Molecular Biology, Neurology, Physiology, Public Health, Environmental and Occupational Health, and Virology.

The scientist has contributed research on diverse topics, including:

  • Genomics, phytochemicals, and oxidative stress
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Parkinson's Disease Mechanisms and Treatments
  • Mosquito-borne diseases and control
  • Lipid Membrane Structure and Behavior
  • Rabies epidemiology and control
  • Heme Oxygenase-1 and Carbon Monoxide

Akaike's recent publications cover a range of specialized subjects and have appeared in several scientific venues. Notable papers include:

  • "Multiplex Neural Circuit Tracing With G-Deleted Rabies Viral Vectors," 2020, Frontiers in Neural Circuits
  • "Protective effects of Nrf2-ARE activator on dopaminergic neuronal loss in Parkinson disease model mice: Possible involvement of heme oxygenase-1," 2020, Neuroscience Letters
  • "Therapeutic effect of a novel curcumin derivative GT863 on a mouse model of amyotrophic lateral sclerosis," 2021, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
  • "In vivo brain ischemia-reperfusion model induced by hypoxia-reoxygenation using zebrafish larvae," 2021, Brain Research Bulletin
  • "Isolation and Purification of Harpagogenin as an Nrf2-ARE Activator from the Tubers of Chinese Artichoke (Stachys sieboldii)," 2023, Biological and Pharmaceutical Bulletin

The scientist has published multiple times in venues such as the Proceedings for Annual Meeting of The Japanese Pharmacological Society, Frontiers in Neural Circuits, Neuroscience Letters, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, and Brain Research Bulletin.

Frequent collaborators include:

  • Yasuhiko Izumi
  • Toshiaki Kume
  • Yuki Takada-Takatori
  • Yutaka Kōyama
  • Katsuharu Tsuchida

The research contributions of Akinori Akaike reflect interests across molecular and neurological mechanisms of diseases, including Parkinson's disease and amyotrophic lateral sclerosis, with additional attention to neuroprotective pathways, viral vector techniques, and phytochemical activators related to oxidative stress. This scholarly profile highlights a multidisciplinary approach in both basic and applied biological sciences.

Best Publications

  • Toward the generation of rod and cone photoreceptors from mouse, monkey and human embryonic stem cells

    Fumitaka Osakada;Hanako Ikeda;Michiko Mandai;Takafumi Wataya

  • α7 Nicotinic Receptor Transduces Signals to Phosphatidylinositol 3-Kinase to Block A β-Amyloid-induced Neurotoxicity

    Takeshi Kihara;Shun Shimohama;Hideyuki Sawada;Kazuhiro Honda

  • Nicotinic receptor stimulation protects neurons against beta-amyloid toxicity

    T. Kihara;S. Shimohama;H. Sawada;J. Kimura

  • Localization of fractalkine and CX3CR1 mRNAs in rat brain: does fractalkine play a role in signaling from neuron to microglia?

    Atsushi Nishiyori;Masabumi Minami;Yoshikazu Ohtani;Shinya Takami

  • Microglia-derived interleukin-6 and leukaemia inhibitory factor promote astrocytic differentiation of neural stem/progenitor cells

    Masaya Nakanishi;Tetsuhiro Niidome;Satoru Matsuda;Akinori Akaike

  • Wnt Signaling Promotes Regeneration in the Retina of Adult Mammals

    Fumitaka Osakada;Sotaro Ooto;Tadamichi Akagi;Michiko Mandai

  • Nicotine-induced protection of cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity.

    Akinori Akaike;Yutaka Tamura;Takeharu Yokota;Shun Shimohama

  • ESTRADIOL PROTECTS MESENCEPHALIC DOPAMINERGIC NEURONS FROM OXIDATIVE STRESS-INDUCED NEURONAL DEATH

    Hideyuki Sawada;Masakazu Ibi;Takeshi Kihara;Makoto Urushitani

  • Phosphatidylinositol 3‐kinase mediates neuroprotection by estrogen in cultured cortical neurons

    Kazuhiro Honda;Hideyuki Sawada;Takeshi Kihara;Makoto Urushitani

  • Protective effects of 1α,25-(OH)2D3 against the neurotoxicity of glutamate and reactive oxygen species in mesencephalic culture

    M Ibi;H Sawada;M Nakanishi;T Kume

  • Flavonols and flavones as BACE-1 inhibitors: structure-activity relationship in cell-free, cell-based and in silico studies reveal novel pharmacophore features.

    Yoshiari Shimmyo;Takeshi Kihara;Akinori Akaike;Tetsuhiro Niidome

  • Nicotinic Acetylcholine Receptor-Mediated Neuroprotection by Donepezil Against Glutamate Neurotoxicity in Rat Cortical Neurons

    Yuki Takada;Atsushi Yonezawa;Toshiaki Kume;Hiroshi Katsuki

  • A critical role of TRPM2 in neuronal cell death by hydrogen peroxide

    Shuji Kaneko;Seiko Kawakami;Yuji Hara;Minoru Wakamori

  • Resveratrol protects dopaminergic neurons in midbrain slice culture from multiple insults.

    Mitsugi Okawara;Hiroshi Katsuki;Emi Kurimoto;Haruki Shibata

  • Nicotine protects cultured cortical neurons against glutamate-induced cytotoxicity via α7-neuronal receptors and neuronal CNS receptors

    Satoshi Kaneko;Takehiko Maeda;Toshiaki Kume;Hanae Kochiyama

  • Stimulation of α4β2 nicotinic acetylcholine receptors inhibits β-amyloid toxicity

    T Kihara;S Shimohama;M Urushitani;H Sawada

  • Acetylcholinesterase inhibitors used in treatment of Alzheimer's disease prevent glutamate neurotoxicity via nicotinic acetylcholine receptors and phosphatidylinositol 3-kinase cascade.

    Yuki Takada-Takatori;Toshiaki Kume;Mitsuhiro Sugimoto;Hiroshi Katsuki

  • Analgesia induced by microinjection of morphine into, and electrical stimulation of, the nucleus reticularis paragigantocellularis of rat medulla oblongata

    A. Akaike;T. Shibata;M. Satoh;H. Takagi

  • Mechanisms of Neuroprotective Effects of Nicotine and Acetylcholinesterase Inhibitors: Role of α4 and α7 Receptors in Neuroprotection

    Akinori Akaike;Yuki Takada-Takatori;Toshiaki Kume;Yasuhiko Izumi

  • Mechanisms of antiapoptotic effects of estrogens in nigral dopaminergic neurons

    Hideyuki Sawada;Masakazu Ibi;Takeshi Kihara;Makoto Urushitani

Frequent Co-Authors

Shuji Kaneko
Shuji Kaneko Kyoto University
Shun Shimohama
Shun Shimohama Sapporo Medical University
Masashi Sasa
Masashi Sasa Hiroshima University
Takeshi Kihara
Takeshi Kihara Kyoto University
Jun Kimura
Jun Kimura University of Iowa
Hiroshi Takagi
Hiroshi Takagi Okinawa Institute of Science and Technology
Ryosuke Takahashi
Ryosuke Takahashi Kyoto University
Hiroshi Takagi
Hiroshi Takagi Nara Institute of Science and Technology
Yoshimi Misu
Yoshimi Misu Yokohama City University
Yoshio Goshima
Yoshio Goshima Yokohama City University

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