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Microbiology

D-Index
69
Citations
16046
World Ranking
2063
National Ranking
63

Overview

Hiroshi Takagi is affiliated with the Nara Institute of Science and Technology in Japan. The researcher's work centers on the field of Biochemistry, Genetics and Molecular Biology, with a significant focus on Molecular Biology as a subfield. Their research spans multiple related areas including Food Science, Cell Biology, Plant Science, and Physiology.

Their main topics of study encompass:

  • Fungal and yeast genetics research
  • Microbial Metabolic Engineering and Bioproduction
  • Fermentation and Sensory Analysis
  • Polyamine Metabolism and Applications
  • Endoplasmic Reticulum Stress and Disease
  • Nitric Oxide and Endothelin Effects
  • Biofuel production and bioconversion

Takagi has contributed to numerous publications, including:

  • "Crystal structure of a YeeE/YedE family protein engaged in thiosulfate uptake" (2020) published in Science Advances
  • "Molecular mechanisms and highly functional development for stress tolerance of the yeast Saccharomyces cerevisiae" (2021) published in Bioscience Biotechnology and Biochemistry
  • "High-Level Production of Lysine in the Yeast Saccharomyces cerevisiae by Rational Design of Homocitrate Synthase" (2021) published in Applied and Environmental Microbiology
  • "Genomic stability and adaptation of beer brewing yeasts during serial repitching in the brewery" (2020) published in bioRxiv (Cold Spring Harbor Laboratory)
  • "Enhancement of lysine biosynthesis confers high-temperature stress tolerance to Escherichia coli cells" (2021) published in Applied Microbiology and Biotechnology

Frequent co-authors in Takagi's research include:

  • Akira Nishimura
  • Ryoya Tanahashi
  • Shota Isogai
  • Ryo Nasuno
  • Yoichi Toyokawa

The researcher's work is often disseminated through several prominent scientific publication venues such as:

  • Bioscience Biotechnology and Biochemistry
  • FEMS Yeast Research
  • Applied Microbiology and Biotechnology
  • Yeast
  • Applied and Environmental Microbiology

Best Publications

  • Microbial alkaline proteases: From a bioindustrial viewpoint

    C.Ganesh Kumar;Hiroshi Takagi

  • Requirement of pro-sequence for the production of active subtilisin E in Escherichia coli.

    H Ikemura;H Takagi;M Inouye

  • Loss of H19 Imprinting in Esophageal Cancer

    Kenji Hibi;Hajime Nakamura;Atsushi Hirai;Yoshihiro Fujikake

  • Proline as a stress protectant in yeast: physiological functions, metabolic regulations, and biotechnological applications

    Hiroshi Takagi

  • Loss of α-tubulin polyglutamylation in ROSA22 mice is associated with abnormal targeting of KIF1A and modulated synaptic function

    Koji Ikegami;Robb L. Heier;Midori Taruishi;Hiroshi Takagi

  • Production and characterization of keratinase of a feather-degrading Bacillus licheniformis PWD-1

    Shu-Wen Cheng;Hsien-Ming Hu;Shu-Whei Shen;Hiroshi Takagi

  • Identification and Functional Analysis of Escherichia coli Cysteine Desulfhydrases

    Naoki Awano;Masaru Wada;Hirotada Mori;Shigeru Nakamori

  • ε-Poly- L -lysine dispersity is controlled by a highly unusual nonribosomal peptide synthetase

    Kazuya Yamanaka;Chitose Maruyama;Chitose Maruyama;Hiroshi Takagi;Hiroshi Takagi;Yoshimitsu Hamano

  • Enhancement of the thermostability of subtilisin E by introduction of a disulfide bond engineered on the basis of structural comparison with a thermophilic serine protease

    H Takagi;T Takahashi;H Momose;M Inouye

  • Metabolic engineering of Saccharomyces cerevisiae for astaxanthin production and oxidative stress tolerance.

    Ken Ukibe;Keisuke Hashida;Nobuyuki Yoshida;Hiroshi Takagi

  • The L-cysteine/L-cystine shuttle system provides reducing equivalents to the periplasm in Escherichia coli.

    Iwao Ohtsu;Natthawut Wiriyathanawudhiwong;Susumu Morigasaki;Takeshi Nakatani

  • Isolation of freeze-tolerant laboratory strains of Saccharomyces cerevisiae from proline-analogue-resistant mutants.

    H Takagi;F Iwamoto;S Nakamori

  • Effect of L-proline on sake brewing and ethanol stress in Saccharomyces cerevisiae.

    Hiroshi Takagi;Miki Takaoka;Akari Kawaguchi;Yoshito Kubo

  • Molecular Cloning of the Gene for Microbial Transglutaminase from Streptoverticillium and Its Expression in Streptomyces lividans

    Kinya Washizu;Keiichi Ando;Satoshi Koikeda;Susumu Hirose

  • The nucleus reticularis gigantocellularis of the medulla oblongata is a highly sensitive site in the production of morphine analgesia in the rat

    Hiroshi Takagi;Masamichi Satoh;Akinori Akaike;Takashi Shibata

  • Proline accumulation by mutation or disruption of the proline oxidase gene improves resistance to freezing and desiccation stresses in Saccharomyces cerevisiae

    Hiroshi Takagi;Kuumi Sakai;Kana Morida;Shigeru Nakamori

  • Folding pathway mediated by an intramolecular chaperone: propeptide release modulates activation precision of pro-subtilisin.

    Yukihiro Yabuta;Yukihiro Yabuta;Hiroshi Takagi;Masayori Inouye;Ujwal Shinde

  • N-Acetyltransferase Mpr1 confers ethanol tolerance on Saccharomyces cerevisiae by reducing reactive oxygen species

    Xiaoyi Du;Hiroshi Takagi

  • Overproduction of l-Cysteine and l-Cystine by Escherichia coli Strains with a Genetically Altered Serine Acetyltransferase

    Shigeru Nakamori;Shin-ichiro Kobayashi;Chitose Kobayashi;Hiroshi Takagi

  • Role of the yeast acetyltransferase Mpr1 in oxidative stress: Regulation of oxygen reactive species caused by a toxic proline catabolism intermediate

    Michiyo Nomura;Hiroshi Takagi

Frequent Co-Authors

Akimasa Nakao
Akimasa Nakao Nagoya University
Hiroshi Ueda
Hiroshi Ueda Kyoto University
Masayori Inouye
Masayori Inouye Rutgers, The State University of New Jersey
Shinobu Inagaki
Shinobu Inagaki Osaka University
Akinori Akaike
Akinori Akaike Kyoto University
Hidemi Misawa
Hidemi Misawa Keio University
Makoto Sato
Makoto Sato University of Fukui
Sakayu Shimizu
Sakayu Shimizu Kyoto University

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