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Takeshi Kihara

Takeshi Kihara

D-Index & Metrics

Neuroscience

D-Index
47
Citations
8144
World Ranking
6453
National Ranking
211

Overview

Takeshi Kihara is affiliated with Kyoto University in Japan and has contributed to the field of biochemistry, genetics, and molecular biology. Their research primarily focuses on pluripotent stem cells, congenital heart defects, and genomics related to rare diseases. Their work is situated within the subfields of molecular biology and genetics.

The scientist has published in venues such as Stem Cell Research. A notable paper includes "Human induced pluripotent stem cells generated from a patient with idiopathic basal ganglia calcification," published in 2021. This publication contributed to the ongoing research on stem cell generation and its applications.

The main topics covered in their research are:

  • Pluripotent Stem Cells Research
  • Congenital heart defects research
  • Genomics and Rare Diseases

Frequent co-authors collaborating with Takeshi Kihara include:

  • Yuichiro Yada
  • Takayuki Kondo
  • Mika Suga
  • Kayoko Tsukita
  • Takako Enami

The scientist's expertise aligns with rigorous investigation in molecular biology techniques and genetic analysis related to developmental and rare disease contexts. The combination of research topics illustrates a multidisciplinary approach linking stem cell technology with genetic disorders and congenital abnormalities.

Best Publications

  • α7 Nicotinic Receptor Transduces Signals to Phosphatidylinositol 3-Kinase to Block A β-Amyloid-induced Neurotoxicity

    Takeshi Kihara;Shun Shimohama;Hideyuki Sawada;Kazuhiro Honda

  • Nicotinic receptor stimulation protects neurons against beta-amyloid toxicity

    T. Kihara;S. Shimohama;H. Sawada;J. Kimura

  • Microglia-derived interleukin-6 and leukaemia inhibitory factor promote astrocytic differentiation of neural stem/progenitor cells

    Masaya Nakanishi;Tetsuhiro Niidome;Satoru Matsuda;Akinori Akaike

  • ESTRADIOL PROTECTS MESENCEPHALIC DOPAMINERGIC NEURONS FROM OXIDATIVE STRESS-INDUCED NEURONAL DEATH

    Hideyuki Sawada;Masakazu Ibi;Takeshi Kihara;Makoto Urushitani

  • Phosphatidylinositol 3‐kinase mediates neuroprotection by estrogen in cultured cortical neurons

    Kazuhiro Honda;Hideyuki Sawada;Takeshi Kihara;Makoto Urushitani

  • Stimulation of α4β2 nicotinic acetylcholine receptors inhibits β-amyloid toxicity

    T Kihara;S Shimohama;M Urushitani;H Sawada

  • Mechanisms of antiapoptotic effects of estrogens in nigral dopaminergic neurons

    Hideyuki Sawada;Masakazu Ibi;Takeshi Kihara;Makoto Urushitani

  • Alzheimer's disease and acetylcholine receptors.

    Takeshi Kihara;Shun Shimohama

  • Dopamine D2-type agonists protect mesencephalic neurons from glutamate neurotoxicity: mechanisms of neuroprotective treatment against oxidative stress.

    Hideyuki Sawada;Masakazu Ibi;Takeshi Kihara;Makoto Urushitani

  • Nonhypotensive Dose of Telmisartan Attenuates Cognitive Impairment Partially Due to Peroxisome Proliferator-Activated Receptor-γ Activation in Mice With Chronic Cerebral Hypoperfusion

    Kazuo Washida;Masafumi Ihara;Keiko Nishio;Youshi Fujita

  • Exercise Is More Effective than Diet Control in Preventing High Fat Diet-induced β-Amyloid Deposition and Memory Deficit in Amyloid Precursor Protein Transgenic Mice

    Masato Maesako;Kengo Uemura;Masakazu Kubota;Akira Kuzuya

  • N‐methyl‐D‐aspartate receptor‐mediated mitochondrial Ca2+ overload in acute excitotoxic motor neuron death: A mechanism distinct from chronic neurotoxicity after Ca2+ influx

    Makoto Urushitani;Tomoki;Nakamizo;Ryotaku Inoue

  • Characterization of sequential N-cadherin cleavage by ADAM10 and PS1

    Kengo Uemura;Takeshi Kihara;Akira Kuzuya;Katsuya Okawa

  • Nongenomic antiapoptotic signal transduction by estrogen in cultured cortical neurons.

    Kazuhiro Honda;Shun Shimohama;Hideyuki Sawada;Takeshi Kihara

  • Neuroprotection by donepezil against glutamate excitotoxicity involves stimulation of α7 nicotinic receptors and internalization of NMDA receptors

    H Shen;T Kihara;H Hongo;X Wu

  • Galantamine modulates nicotinic receptor and blocks Abeta-enhanced glutamate toxicity.

    Takeshi Kihara;Hideyuki Sawada;Tomoki Nakamizo;Rie Kanki

  • Multifunction of Myricetin on Aβ : Neuroprotection Via a Conformational Change of Aβ and Reduction of Aβ Via the Interference of Secretases

    Yoshiari Shimmyo;Takeshi Kihara;Akinori Akaike;Tetsuhiro Niidome

  • Nicotinic receptor–mediated protection against β-amyloid neurotoxicity

    Shun Shimohama;Takeshi Kihara

  • Proteasome Mediates Dopaminergic Neuronal Degeneration, and Its Inhibition Causes α-Synuclein Inclusions

    Hideyuki Sawada;Ryuichi Kohno;Takeshi Kihara;Yasuhiko Izumi

  • Epigallocatechin-3-gallate and curcumin suppress amyloid beta-induced beta-site APP cleaving enzyme-1 upregulation.

    Yoshiari Shimmyo;Takeshi Kihara;Akinori Akaike;Tetsuhiro Niidome

  • Nicotinic receptor stimulation protects nigral dopaminergic neurons in rotenone-induced Parkinson's disease models.

    Hiroki Takeuchi;Takashi Yanagida;Masatoshi Inden;Kazuyuki Takata

Frequent Co-Authors

Hiroshi Shibasaki
Hiroshi Shibasaki Kyoto University
Masafumi Ihara
Masafumi Ihara Kyoto University
Shuji Kaneko
Shuji Kaneko Kyoto University
Akio Ikeda
Akio Ikeda Kyoto University
Hidenao Fukuyama
Hidenao Fukuyama Kyoto University
Bradley T. Hyman
Bradley T. Hyman Harvard University
Takashi Hanakawa
Takashi Hanakawa Kyoto University

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