What is he best known for?
The fields of study he is best known for:
- Enzyme
- Apoptosis
- Internal medicine
His primary areas of investigation include Internal medicine, Endocrinology, Neuroprotection, Neurotoxicity and Cell biology.
His Endocrinology research is multidisciplinary, relying on both Stroke and Alzheimer's disease.
Takeshi Kihara combines subjects such as Dopaminergic, Protein kinase B and Kinase, MAPK/ERK pathway with his study of Neuroprotection.
Other disciplines of study, such as Glutamate receptor, Estrogen and Mitochondrion, are mixed together with his Neurotoxicity studies.
The concepts of his Glutamate receptor study are interwoven with issues in NMDA receptor and Motor neuron.
His Cell biology study incorporates themes from Biochemistry and Astrocyte.
His most cited work include:
- α7 Nicotinic Receptor Transduces Signals to Phosphatidylinositol 3-Kinase to Block A β-Amyloid-induced Neurotoxicity (390 citations)
- Nicotinic receptor stimulation protects neurons against β‐amyloid toxicity (305 citations)
- Phosphatidylinositol 3‐kinase mediates neuroprotection by estrogen in cultured cortical neurons (228 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Cell biology, Glutamate receptor, Neuroprotection, Internal medicine and Endocrinology.
The Cell biology study combines topics in areas such as Biochemistry, Presenilin and Amyloid precursor protein.
His work deals with themes such as NMDA receptor and Pharmacology, which intersect with Glutamate receptor.
In his study, Protein kinase A is strongly linked to Dopaminergic, which falls under the umbrella field of Neuroprotection.
His study in Internal medicine is interdisciplinary in nature, drawing from both Progenitor cell and Apoptosis.
His studies in Endocrinology integrate themes in fields like Receptor and Cognitive decline.
He most often published in these fields:
- Cell biology (36.63%)
- Glutamate receptor (27.72%)
- Neuroprotection (27.72%)
What were the highlights of his more recent work (between 2007-2018)?
- Cell biology (36.63%)
- Amyloid precursor protein (17.82%)
- Internal medicine (24.75%)
In recent papers he was focusing on the following fields of study:
Cell biology, Amyloid precursor protein, Internal medicine, Biochemistry and Endocrinology are his primary areas of study.
His Cell biology study integrates concerns from other disciplines, such as Molecular biology and Presenilin.
His work carried out in the field of Amyloid precursor protein brings together such families of science as HEK 293 cells, Amyloid beta and Neuroscience.
Takeshi Kihara has researched Biochemistry in several fields, including Amyloid precursor protein secretase, Beta, Neuroprotection and Senile plaques.
His research integrates issues of Biophysics, Neurodegeneration and Thioflavin in his study of Neuroprotection.
His Endocrinology study combines topics from a wide range of disciplines, such as Receptor and Cognitive decline.
Between 2007 and 2018, his most popular works were:
- Flavonols and flavones as BACE-1 inhibitors: structure-activity relationship in cell-free, cell-based and in silico studies reveal novel pharmacophore features. (138 citations)
- Exercise Is More Effective than Diet Control in Preventing High Fat Diet-induced β-Amyloid Deposition and Memory Deficit in Amyloid Precursor Protein Transgenic Mice (103 citations)
- Nonhypotensive Dose of Telmisartan Attenuates Cognitive Impairment Partially Due to Peroxisome Proliferator-Activated Receptor-γ Activation in Mice With Chronic Cerebral Hypoperfusion (102 citations)
In his most recent research, the most cited papers focused on:
- Enzyme
- Apoptosis
- Internal medicine
Takeshi Kihara mostly deals with Amyloid precursor protein, Pharmacology, Neuroprotection, Internal medicine and Endocrinology.
His work on P3 peptide as part of general Amyloid precursor protein study is frequently linked to Genetically modified mouse, therefore connecting diverse disciplines of science.
The study incorporates disciplines such as Excitotoxicity, Glutamate receptor, NMDA receptor and Neurodegeneration in addition to Pharmacology.
His work investigates the relationship between Neurodegeneration and topics such as Nicotine that intersect with problems in Nicotinic agonist.
Among his Neuroprotection studies, there is a synthesis of other scientific areas such as Myricetin and Neurotoxicity.
His Endocrinology research incorporates themes from Stroke and Receptor, Antagonist, Peroxisome proliferator-activated receptor.
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