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Medicine

D-Index
86
Citations
30413
World Ranking
14018
National Ranking
7112

Overview

Edson X. Albuquerque was affiliated with the University of Maryland, Baltimore in the United States and contributed to scientific knowledge primarily in the fields of Medicine and Agricultural and Biological Sciences. Their research focused on various aspects of toxicology, pharmacology, and neuroscience, with particular attention to the effects of pesticides and neurotoxic agents.

Their work covered several subfields, including Plant Science, Pharmacology, Health, Toxicology and Mutagenesis, Molecular Biology, and Radiology, Nuclear Medicine and Imaging. Albuquerque's research topics encompassed Pesticide Exposure and Toxicity, Cholinesterase and Neurodegenerative Diseases, Environmental Toxicology and Ecotoxicology, Nicotinic Acetylcholine Receptors Study, Pesticide and Herbicide Environmental Studies, Insect and Pesticide Research, and Neuroscience and Neuropharmacology Research.

Their scientific publications included notable papers such as:

  • "Gestational exposures to organophosphorus insecticides: From acute poisoning to developmental neurotoxicity" (2020, Neuropharmacology)
  • "Learning and memory retention deficits in prepubertal guinea pigs prenatally exposed to low levels of the organophosphorus insecticide malathion" (2020, Neurotoxicology and Teratology)
  • "Oral Pretreatment with Galantamine Effectively Mitigates the Acute Toxicity of a Supralethal Dose of Soman in Cynomolgus Monkeys Posttreated with Conventional Antidotes" (2020, Journal of Pharmacology and Experimental Therapeutics)
  • "Postnatal Guinea Pig Brain Development, as Revealed by Magnetic Resonance and Diffusion Kurtosis Imaging" (2020, Brain Sciences)
  • "(R,S)-trihexyphenidyl, acting via a muscarinic receptor-independent mechanism, inhibits hippocampal glutamatergic and GABAergic synaptic transmissions: Potential relevance for treatment of organophosphorus intoxication" (2023, Neuropharmacology)

Frequent coauthors who collaborated with Albuquerque included Edna F. R. Pereira, Yasco Aracava, Joseph D. Pescrille, William P. Fawcett, and Eric W. Lumsden.

The venues where Albuquerque's work was most frequently published included Neuropharmacology, Neurotoxicology and Teratology, Journal of Pharmacology and Experimental Therapeutics, Brain Sciences, and bioRxiv (Cold Spring Harbor Laboratory).

Best Publications

  • Mammalian nicotinic acetylcholine receptors: from structure to function.

    Edson X. Albuquerque;Edna F. R. Pereira;Manickavasagom Alkondon;Scott W. Rogers

  • NMDAR inhibition-independent antidepressant actions of ketamine metabolites

    Panos Zanos;Ruin Moaddel;Patrick J. Morris;Polymnia Georgiou

  • Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms

    Panos Zanos;Ruin Moaddel;Patrick J. Morris;Lace M. Riggs

  • The Brain Metabolite Kynurenic Acid Inhibits α7 Nicotinic Receptor Activity and Increases Non-α7 Nicotinic Receptor Expression: Physiopathological Implications

    Corey Hilmas;Edna F. R. Pereira;Manickavasagom Alkondon;Arash Rassoulpour

  • International Union of Pharmacology. XX. Current Status of the Nomenclature for Nicotinic Acetylcholine Receptors and Their Subunits

    R. J. Lukas;J.-P. Changeux;N. Le Novere;E. X. Albuquerque

  • Properties of Neuronal Nicotinic Acetylcholine Receptors: Pharmacological Characterization and Modulation of Synaptic Function,

    Edson X. Albuquerque;Manickavasagom Alkondon;Edna F. R. Pereira;Newton G. Castro

  • Choline is a Selective Agonist of α7 Nicotinic Acetylcholine Receptors in the Rat Brain Neurons

    M. Alkondon;E. F. R. Pereira;W. S. Cortes;W. S. Cortes;A. Maelicke

  • NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVATION MODULATES GAMMA -AMINOBUTYRIC ACID RELEASE FROM CA1 NEURONS OF RAT HIPPOCAMPAL SLICES

    Manickavasagom Alkondon;Edna F. R. Pereira;Catão T. F. Barbosa;Edson X. Albuquerque

  • Choline and selective antagonists identify two subtypes of nicotinic acetylcholine receptors that modulate GABA release from CA1 interneurons in rat hippocampal slices.

    Manickavasagom Alkondon;Edna F. R. Pereira;Howard M. Eisenberg;Edson X. Albuquerque

  • Galantamine Is an Allosterically Potentiating Ligand of Neuronal Nicotinic but Not of Muscarinic Acetylcholine Receptors

    Marek Samochocki;Anja Höffle;Andreas Fehrenbacher;Ruth Jostock

  • Allosteric sensitization of nicotinic receptors by galantamine, a new treatment strategy for Alzheimer's disease.

    Alfred Maelicke;Marek Samochocki;Ruth Jostock;Andreas Fehrenbacher

  • α-Bungarotoxin-and methyllycaconitine-sensitive nicotinic receptors mediate fast synaptic transmission in interneurons of rat hippocampal slices

    Manickavasagom Alkondon;Edna F.R. Pereira;Edson X. Albuquerque;Edson X. Albuquerque

  • Nicotinic Receptor Activation in Human Cerebral Cortical Interneurons: a Mechanism for Inhibition and Disinhibition of Neuronal Networks

    Manickavasagom Alkondon;Edna F. R. Pereira;Howard M. Eisenberg;Edson X. Albuquerque

  • Human vascular endothelial cells express functional nicotinic acetylcholine receptors

    Kevin D. Macklin;Arno D. J. Maus;Edna F. R. Pereira;Edson X. Albuquerque

  • alpha-Bungarotoxin-sensitive hippocampal nicotinic receptor channel has a high calcium permeability.

    N.G. Castro;E.X. Albuquerque

  • Nicotinic Acetylcholine Receptor α7 and α4β2 Subtypes Differentially Control GABAergic Input to CA1 Neurons in Rat Hippocampus

    Manickavasagom Alkondon;Edson X. Albuquerque;Edson X. Albuquerque

  • Agonist responses of neuronal nicotinic acetylcholine receptors are potentiated by a novel class of allosterically acting ligands.

    A. Schrattenholz;E. F. R. Pereira;U. Roth;K.-H. Weber

  • Allosteric modulation of nicotinic acetylcholine receptors as a treatment strategy for Alzheimer's disease.

    Alfred Maelicke;Edson X Albuquerque

  • Human and Rodent Bronchial Epithelial Cells Express Functional Nicotinic Acetylcholine Receptors

    Arno D. J. Maus;Edna F. R. Pereira;Peter I. Karachunski;Robert M. Horton

  • A nicotinic acetylcholine receptor regulating cell adhesion and motility is expressed in human keratinocytes.

    Sergei A. Grando;Robert M. Horton;Edna F.R. Pereira;Brenda M. Diethelm-Okita

Frequent Co-Authors

Alfred Maelicke
Alfred Maelicke Johannes Gutenberg University of Mainz
John W. Daly
John W. Daly National Institutes of Health
Bernhard Witkop
Bernhard Witkop National Institutes of Health
Robert Schwarcz
Robert Schwarcz University of Maryland, Baltimore
Todd D. Gould
Todd D. Gould University of Maryland, Baltimore
Craig J. Thomas
Craig J. Thomas National Institutes of Health
Ruin Moaddel
Ruin Moaddel National Institutes of Health
Carlos A. Zarate
Carlos A. Zarate National Institutes of Health
Scott M. Thompson
Scott M. Thompson University of Colorado Anschutz Medical Campus
John E. Rash
John E. Rash Colorado State University

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