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Biology and Biochemistry

D-Index
77
Citations
15587
World Ranking
4901
National Ranking
2351

Overview

Sergei A. Grando is affiliated with the University of California, Irvine, in the United States. Their research mainly focuses on medicine with a strong emphasis in pathology and forensic medicine, genetics, rheumatology, molecular biology, and radiology. Their work covers several specialized subfields and topics relevant to autoimmune and immunological conditions.

The scientist has contributed substantially to the study of autoimmune bullous skin diseases, coagulation, bradykinin, polyphosphates, angioedema, urticaria and related conditions, receptor mechanisms and signaling, monoclonal and polyclonal antibody research, nicotinic acetylcholine receptors, and vagus nerve stimulation research.

Sergei A. Grando has published a notable number of papers in key scientific venues. Frequent publication venues include:

  • International Immunopharmacology
  • Journal of Biological Chemistry
  • Journal of Investigative Dermatology
  • Antibodies
  • Toxins

Significant recent papers authored or coauthored by Sergei A. Grando include:

  • "A historic perspective on the current progress in elucidation of the biologic significance of non-neuronal acetylcholine," 2020, International Immunopharmacology
  • "Mechanisms of synergy of autoantibodies to M3 muscarinic acetylcholine receptor and secretory pathway Ca2+/Mn2+-ATPase isoform 1 in patients with non-desmoglein pemphigus vulgaris," 2020, International Immunopharmacology
  • "Mitochondrial Autoantibodies and the Role of Apoptosis in Pemphigus Vulgaris," 2022, Antibodies
  • "Atypical pemphigus: autoimmunity against desmocollins and other non-desmoglein autoantigens," 2021, Italian Journal of Dermatology and Venereology
  • "Chronic exposure to the anti-M3 muscarinic acetylcholine receptor autoantibody in pemphigus vulgaris contributes to disease pathophysiology," 2022, Journal of Biological Chemistry

The researcher has collaborated frequently with several coauthors, such as:

  • Alex I. Chernyavsky
  • Anna-Marie Hosking
  • Krupa G. Patel
  • Karen Brami-Cherrier
  • Alex Chernavsky

Best Publications

  • Definitions and outcome measures for bullous pemphigoid: Recommendations by an international panel of experts

    Dedee F. Murrell;Benjamin S. Daniel;Pascal Joly;Luca Borradori

  • Connections of nicotine to cancer

    Sergei A. Grando

  • Human keratinocytes synthesize, secrete, and degrade acetylcholine

    Sergei A. Grando;David A. Kist;Mei Qi;Mark V. Dahl

  • Diagnosis and management of pemphigus: Recommendations of an international panel of experts

    Dedee F. Murrell;Sandra Peña;Sandra Peña;Pascal Joly;Branka Marinovic

  • Biological Functions of Keratinocyte Cholinergic Receptors

    Sergei A. Grando

  • Classification, clinical manifestations, and immunopathological mechanisms of the epithelial variant of paraneoplastic autoimmune multiorgan syndrome: a reappraisal of paraneoplastic pemphigus.

    Vu Thuong Nguyen;Assane Ndoye;Karl D. Bassler;Leonard D. Shultz

  • Adrenergic and Cholinergic Control in the Biology of Epidermis: Physiological and Clinical Significance

    Sergei A. Grando;Mark R. Pittelkow;Karin U. Schallreuter

  • Novel Human α9 Acetylcholine Receptor Regulating Keratinocyte Adhesion is Targeted by Pemphigus Vulgaris Autoimmunity

    Vu Thuong Nguyen;Assane Ndoye;Sergei A. Grando

  • A nicotinic acetylcholine receptor regulating cell adhesion and motility is expressed in human keratinocytes.

    Sergei A. Grando;Robert M. Horton;Edna F.R. Pereira;Brenda M. Diethelm-Okita

  • Receptor-mediated tobacco toxicity: cooperation of the Ras/Raf-1/MEK1/ERK and JAK-2/STAT-3 pathways downstream of α7 nicotinic receptor in oral keratinocytes

    Juan Arredondo;Alexander I. Chernyavsky;David L. Jolkovsky;Kent E. Pinkerton

  • The non-neuronal cholinergic system of human skin.

    H Kurzen;I Wessler;C J Kirkpatrick;K Kawashima

  • Nicotine enhances expression of the alpha 3, alpha 4, alpha 5, and alpha 7 nicotinic receptors modulating calcium metabolism and regulating adhesion and motility of respiratory epithelial cells.

    S. Zia;A. Ndoye;Vu Thuong Nguyen;S. A. Grando

  • Activation of keratinocyte nicotinic cholinergic receptors stimulates calcium influx and enhances cell differentiation.

    Sergei A. Grando;Robert M. Horton;Theodora M. Mauro;David A. Kist

  • Pemphigus autoimmunity: Hypotheses and realities

    Sergei A Grando

  • Antibodies against keratinocyte antigens other than desmogleins 1 and 3 can induce pemphigus vulgaris–like lesions

    Vu Thuong Nguyen;Assane Ndoye;Leonard D. Shultz;Mark R. Pittelkow

  • Biological Effects of SLURP-1 on Human Keratinocytes

    Juan Arredondo;Alexander I. Chernyavsky;Robert J. Webber;Sergei A. Grando

  • The Nicotinic Acetylcholine Receptor: Structure and Autoimmune Pathology

    Bianca M. Conti-tronconi;Kathryn E. McLane;Michael A. Raftery;Sergei A. Grando

  • M3 muscarinic receptor antagonists inhibit small cell lung carcinoma growth and mitogen-activated protein kinase phosphorylation induced by acetylcholine secretion.

    Pingfang Song;Harmanjatinder S. Sekhon;Allison Lu;Juan Arredondo

  • Desmoglein Versus Non-desmoglein Signaling in Pemphigus Acantholysis CHARACTERIZATION OF NOVEL SIGNALING PATHWAYS DOWNSTREAM OF PEMPHIGUS VULGARIS ANTIGENS

    Alex I. Chernyavsky;Juan Arredondo;Yasuo Kitajima;Miki Sato-Nagai

  • Central role of α7 nicotinic receptor in differentiation of the stratified squamous epithelium

    Juan Arredondo;Vu Thuong Nguyen;Alexander I. Chernyavsky;Dani Bercovich

Frequent Co-Authors

Wolfgang Kummer
Wolfgang Kummer University of Giessen
Koichiro Kawashima
Koichiro Kawashima Kitasato University
Victoria P. Werth
Victoria P. Werth University of Pennsylvania
Jean-Claude Bystryn
Jean-Claude Bystryn New York University
Marcel F. Jonkman
Marcel F. Jonkman University Medical Center Groningen
Detlef Zillikens
Detlef Zillikens University of Lübeck
Masayuki Amagai
Masayuki Amagai Keio University
Avi Orr-Urtreger
Avi Orr-Urtreger Tel Aviv University
Leonard D. Shultz
Leonard D. Shultz Jackson Laboratory

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