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Neuroscience

D-Index
77
Citations
23451
World Ranking
1827
National Ranking
191

Overview

Susan Wonnacott is affiliated with the University of Bath in the United Kingdom. Their research spans multiple areas within biochemistry, genetics, molecular biology, and neuroscience, with a focus on molecular biology and cognitive and cellular neuroscience subfields. The scientist's work incorporates experimental approaches related to receptor mechanisms, signaling, and neurotransmitter receptor influence on behavior.

Their recent publications cover topics that include nicotinic acetylcholine receptors, sleep and wakefulness, ion channel regulation, and the neuroscience of respiration. A sample of recent papers includes the following:

  • The Bidirectional Relationship Between Sleep and Inflammation Links Traumatic Brain Injury and Alzheimer's Disease, 2020, Frontiers in Neuroscience
  • A conserved arginine with non-conserved function is a key determinant of agonist selectivity in α7 nicotinic ACh receptors, 2021, British Journal of Pharmacology
  • Contrasting effects of the α7 nicotinic receptor antagonist methyllycaconitine in different rat models of heroin reinstatement, 2021, Journal of Psychopharmacology
  • Structural and temporal basis for agonism in the α4β2 nicotinic acetylcholine receptor, 2022, bioRxiv (Cold Spring Harbor Laboratory)
  • Sex Differences in Brain Region-Specific Activation of c-Fos following Kappa Opioid Receptor Stimulation or Acute Stress in Mice, 2023, International Journal of Molecular Sciences

Frequent co-authors collaborating with Susan Wonnacott include:

  • Cecilia Gotti
  • Michael J. Marks
  • Neil S. Millar
  • Christopher Bailey
  • Sharon L. Smith

The scientist publishes regularly in venues such as the IUPHAR/BPS Guide to Pharmacology CITE, Frontiers in Neuroscience, Journal of Psychopharmacology, bioRxiv (Cold Spring Harbor Laboratory), and the International Journal of Molecular Sciences.

Main fields of study represented by their work include Biochemistry, Genetics, and Molecular Biology with 11 publications, and Neuroscience with 8 publications.

Subfields covered encompass Molecular Biology, Cognitive Neuroscience, Cellular and Molecular Neuroscience, Endocrine and Autonomic Systems, and Experimental and Cognitive Psychology.

Key research topics related to Susan Wonnacott's publications are:

  • Nicotinic Acetylcholine Receptors Study
  • Receptor Mechanisms and Signaling
  • Sleep and Wakefulness Research
  • Ion channel regulation and function
  • Neuroscience of respiration and sleep
  • Sleep and related disorders
  • Neurotransmitter Receptor Influence on Behavior

Best Publications

  • Presynaptic nicotinic ACh receptors.

    Susan Wonnacott

  • Experimental design and analysis and their reporting II: updated and simplified guidance for authors and peer reviewers

    Michael J Curtis;Steve Alexander;Giuseppe Cirino;James R Docherty

  • Experimental design and analysis and their reporting: new guidance for publication in BJP.

    Michael J Curtis;Richard A Bond;Domenico Spina;Amrita Ahluwalia

  • Nicotinic acetylcholine receptors and the regulation of neuronal signalling

    Federico Dajas-Bailador;Susan Wonnacott

  • International Union of Pharmacology. XX. Current Status of the Nomenclature for Nicotinic Acetylcholine Receptors and Their Subunits

    R. J. Lukas;J.-P. Changeux;N. Le Novere;E. X. Albuquerque

  • Goals and practicalities of immunoblotting and immunohistochemistry: A guide for submission to the British Journal of Pharmacology.

    Steve P H Alexander;Richard E Roberts;Brad R S Broughton;Christopher G Sobey

  • Characterization of nicotinic receptor-mediated [3H]dopamine release from synaptosomes prepared from mouse striatum.

    Sharon Grady;Michael J. Marks;Susan Wonnacott;Allan C. Collins

  • The paradox of nicotinic acetylcholine receptor upregulation by nicotine

    Susan Wonnacott

  • Presynaptic Nicotinic Modulation of Dopamine Release in the Three Ascending Pathways Studied by In Vivo Microdialysis: Comparison of Naive and Chronic Nicotine‐Treated Rats

    David L. Marshall;Peter H. Redfern;Susan Wonnacott

  • Precise Localization of α7 Nicotinic Acetylcholine Receptors on Glutamatergic Axon Terminals in the Rat Ventral Tegmental Area

    Ian W. Jones;Susan Wonnacott

  • Characterisation of the binding of [3H]methyllycaconitine: a new radioligand for labelling α7-type neuronal nicotinic acetylcholine receptors

    Andrew R.L Davies;David J Hardick;Ian S Blagbrough;Barry V.L Potter

  • Nicotine: from molecular mechanisms to behaviour

    Susan Wonnacott;Nimish Sidhpura;David J K Balfour

  • Blockade of nicotinic currents in hippocampal neurons defines methyllycaconitine as a potent and specific receptor antagonist.

    M. Alkondon;E. F. R. Pereira;S. Wonnacott;E. X. Albuquerque

  • Presynaptic nicotinic receptors modulating dopamine release in the rat striatum

    Susan Wonnacott;Sergio Kaiser;Adrian Mogg;Lev Soliakov

  • Stereoselective nicotine-induced release of dopamine from striatal synaptosomes: concentration dependence and repetitive stimulation.

    Catherine Rapier;George G. Lunt;Susan Wonnacott

  • 6-Hydroxydopamine-induced Apoptosis Is Mediated via Extracellular Auto-oxidation and Caspase 3-dependent Activation of Protein Kinase Cδ

    Katharine Hanrott;Louise Gudmunsen;Michael J. O’Neill;Susan Wonnacott

  • α-Bungarotoxin-Sensitive Nicotinic Receptors Indirectly Modulate [3H]Dopamine Release in Rat Striatal Slices via Glutamate Release

    Sergio Kaiser;Susan Wonnacott

  • Methyllycaconitine: a selective probe for neuronal α-bungarotoxin binding sites

    J.M. Ward;V.B. Cockcroft;G.G. Lunt;F.S. Smillie

  • Nicotinic modulation of [3H]dopamine release from striatal synaptosomes: pharmacological characterisation.

    Catherine Rapier;George G. Lunt;Susan Wonnacott

  • Presynaptic modulation of transmitter release by nicotinic receptors.

    Susan Wonnacott;Jane Irons;Catherine Rapier;Beverley Thorne

  • Nicotine activates the extracellular signal-regulated kinase 1/2 via the alpha7 nicotinic acetylcholine receptor and protein kinase A, in SH-SY5Y cells and hippocampal neurones.

    F. A. Dajas-Bailador;L. Soliakov;S. Wonnacott

  • The α7 nicotinic acetylcholine receptor subtype mediates nicotine protection against NMDA excitotoxicity in primary hippocampal cultures through a Ca2+ dependent mechanism

    Federico A Dajas-Bailador;Pedro A Lima;Susan Wonnacott

  • α6β2* and α4β2* Nicotinic Acetylcholine Receptors As Drug Targets for Parkinson's Disease

    Maryka Quik;Susan Wonnacott

Frequent Co-Authors

Allan C. Collins
Allan C. Collins University of Colorado Boulder
Michael J. O'Neill
Michael J. O'Neill Eli Lilly (United States)
Jeffrey A. Gray
Jeffrey A. Gray King's College London
J. Michael McIntosh
J. Michael McIntosh University of Utah
J. Paul Bolam
J. Paul Bolam University of Oxford
Kelly T. Dineley
Kelly T. Dineley The University of Texas Medical Branch at Galveston

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