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Adrian J. Wolstenholme

Adrian J. Wolstenholme

D-Index & Metrics

Animal Science and Veterinary

D-Index
53
Citations
10047
World Ranking
502
National Ranking
174

Overview

Adrian J. Wolstenholme is affiliated with the University of Georgia in the United States. Their research encompasses several interrelated fields centered on parasitology, veterinary science, environmental science, and medicine.

Their main areas of study include:

  • Medicine
  • Environmental Science
  • Veterinary

Subfields of their work focus on:

  • Infectious Diseases
  • Ecology
  • Small Animals
  • Insect Science
  • Parasitology

Key topics addressed in their publications cover:

  • Parasitic Diseases Research and Treatment
  • Parasite Biology and Host Interactions
  • Helminth infection and control
  • Insect symbiosis and bacterial influences
  • Parasites and Host Interactions
  • Nematode management and characterization studies
  • Coccidia and coccidiosis research

Frequent publication venues include:

  • International Journal for Parasitology Drugs and Drug Resistance
  • International Journal for Parasitology
  • Veterinary Parasitology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS Pathogens

Frequent co-authors in their research are:

  • Barbara J. Reaves
  • Cédric Neveu
  • Connor M. O'Neill
  • Jürgen Krücken
  • Melissa M. George

Selected recent papers include:

  • Evaluation of the in vitro susceptibility of various filarial nematodes to emodepside (2021), published in International Journal for Parasitology Drugs and Drug Resistance
  • Evaluation of changes in drug susceptibility and population genetic structure in Haemonchus contortus following worm replacement as a means to reverse the impact of multiple-anthelmintic resistance on a sheep farm (2021), published in International Journal for Parasitology Drugs and Drug Resistance
  • EAT-18 is an essential auxiliary protein interacting with the non-alpha nAChR subunit EAT-2 to form a functional receptor (2020), published in PLoS Pathogens
  • The avermectin/milbemycin receptors of parasitic nematodes (2021), published in Pesticide Biochemistry and Physiology
  • Genome structure and population genomics of the canine heartworm Dirofilaria immitis (2023), published in International Journal for Parasitology

Best Publications

  • Genome Sequence of the Pea Aphid Acyrthosiphon pisum

    Stephen Richards;Richard A. Gibbs;Nicole M. Gerardo;Nancy Moran

  • Drug resistance in veterinary helminths

    Adrian J. Wolstenholme;Ian Fairweather;Roger Prichard;Georg von Samson-Himmelstjerna

  • Glutamate-gated chloride channels and the mode of action of the avermectin/milbemycin anthelmintics.

    A. J. Wolstenholme;A. T. Rogers

  • The genome and transcriptome of Haemonchus contortus, a key model parasite for drug and vaccine discovery

    Roz Laing;Taisei Kikuchi;Taisei Kikuchi;Axel Martinelli;Isheng J. Tsai;Isheng J. Tsai

  • Characterisation of the binding of [3H]methyllycaconitine: a new radioligand for labelling α7-type neuronal nicotinic acetylcholine receptors

    Andrew R.L Davies;David J Hardick;Ian S Blagbrough;Barry V.L Potter

  • Glutamate-gated Chloride Channels*

    Unknown

  • Molecular basis of resistance of influenza A viruses to amantadine.

    A. J. Hay;M. C. Zambon;A. J. Wolstenholme;J. J. Skehel

  • Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor interactions

    Andrew C. Kotze;Peter W. Hunt;Philip John Skuce;Georg von Samson-Himmelstjerna

  • The Complete Nucleotide Sequence of the Genome of a Hepatitis B Virus Isolated from a Naturally Infected Chimpanzee

    Mark Vaudin;Adrian J. Wolstenholme;Kwesi N. Tsiquaye;Arie J. Zuckerman

  • The genome of the heartworm, Dirofilaria immitis, reveals drug and vaccine targets

    Christelle Godel;Sujai Kumar;Georgios Koutsovoulos;Philipp Ludin

  • GLC-3: a novel fipronil and BIDN-sensitive, but picrotoxinin-insensitive, L-glutamate-gated chloride channel subunit from Caenorhabditis elegans.

    Lucy Horoszok;Valérie Raymond;David B Sattelle;Adrian J Wolstenholme

  • Molecular detection of benzimidazole resistance in Haemonchus contortus using real-time PCR and pyrosequencing.

    G von Samson-Himmelstjerna;T K Walsh;A A Donnan;S Carriere

  • Candidate anthelmintic resistance-associated gene expression and sequence polymorphisms in a triple-resistant field isolate of Haemonchus contortus.

    Sally M. Williamson;Bob Storey;Sue Howell;Kate M. Harper

  • Human peripheral blood mononuclear cells express GABAA receptor subunits.

    Sabina Alam;David L. Laughton;Andrew Walding;Adrian J. Wolstenholme

  • Global Change and Helminth Infections in Grazing Ruminants in Europe: Impacts, Trends and Sustainable Solutions

    Eric R. Morgan;Johannes Charlier;Guy Hendrickx;Annibale Biggeri

  • The avermectin receptors of Haemonchus contortus and Caenorhabditis elegans

    Darran M Yates;Virginia Portillo;Adrian J Wolstenholme

  • An autoradiographic study of the distribution of binding sites for the novel alpha7-selective nicotinic radioligand [3H]-methyllycaconitine in the mouse brain.

    Paul Whiteaker;Andrew R. L. Davies;Michael J. Marks;Ian S. Blagbrough

  • An Ivermectin-Sensitive Glutamate-Gated Chloride Channel from the Parasitic Nematode Haemonchus contortus

    Unknown

  • Ion channels and receptor as targets for the control of parasitic nematodes.

    Unknown

  • Refugia and anthelmintic resistance: Concepts and challenges.

    Jane E. Hodgkinson;Ray M. Kaplan;Fiona Kenyon;Eric R. Morgan

  • Xanthine oxidoreductase in human mammary epithelial cells: activation in response to inflammatory cytokines

    Susanna Page;Debbie Powell;Mustapha Benboubetra;Clifford R. Stevens

  • Replication of lactate dehydrogenase-elevating virus in macrophages. 2. Mechanism of persistent infection in mice and cell culture.

    Johanna A. Stueckemann;Marcia Holth;William J. Swart;Katherine Kowalchyk

  • 2-Aminoethoxydiphenylborane Is an Acute Inhibitor of Directly Photosensitive Retinal Ganglion Cell Activity In Vitro and In Vivo

    Sumathi Sekaran;Gurprit S. Lall;Katherine L. Ralphs;Adrian J. Wolstenholme

  • The nicotinic acetylcholine receptors of the parasitic nematode Ascaris suum: formation of two distinct drug targets by varying the relative expression levels of two subunits.

    Sally M. Williamson;Alan P. Robertson;Laurence Brown;Tracey Williams

  • Nematode ligand-gated chloride channels: an appraisal of their involvement in macrocyclic lactone resistance and prospects for developing molecular markers.

    S McCavera;T K Walsh;A J Wolstenholme

  • Distribution of glutamate-gated chloride channel subunits in the parasitic nematode Haemonchus contortus.

    Virginia Portillo;Suchitra Jagannathan;Adrian J. Wolstenholme

  • An ivermectin-sensitive glutamate-gated chloride channel subunit from Dirofilaria immitis

    Darran M. Yates;Adrian J. Wolstenholme

Frequent Co-Authors

David B. Sattelle
David B. Sattelle University College London
Susan Wonnacott
Susan Wonnacott University of Bath
Barry V. L. Potter
Barry V. L. Potter University of Oxford
Gerald C. Coles
Gerald C. Coles University of Bristol
Martin S. Williamson
Martin S. Williamson Rothamsted Research
Linda M. Field
Linda M. Field Rothamsted Research
Shuji Shigenobu
Shuji Shigenobu National Institute for Basic Biology
Georg von Samson-Himmelstjerna
Georg von Samson-Himmelstjerna Freie Universität Berlin
Philip Skuce
Philip Skuce Moredun Foundation
William L. Pak
William L. Pak Purdue University West Lafayette

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