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Chemistry
Australia
2025

D-Index & Metrics

Chemistry

D-Index
92
Citations
29639
World Ranking
1889
National Ranking
52

Research.com Recognitions

  • 2025 - Research.com Chemistry in Australia Leader Award
  • 2022 - Research.com Chemistry in Australia Leader Award
  • 2017 - Australian Laureate Fellow

Overview

Gottfried Otting is affiliated with the Australian National University in Australia. Their research primarily spans the field of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology, Materials Chemistry, Spectroscopy, Biophysics, and Infectious Diseases as subfields of study.

The scientist's research topics cover a range of areas including:

  • RNA and protein synthesis mechanisms
  • Chemical Synthesis and Analysis
  • Electron Spin Resonance Studies
  • Protein Structure and Dynamics
  • Lanthanide and Transition Metal Complexes
  • Advanced NMR Techniques and Applications
  • SARS-CoV-2 and COVID-19 Research

Recent papers authored or coauthored by the scientist include:

  • Main protease mutants of SARS-CoV-2 variants remain susceptible to nirmatrelvir, 2022, Bioorganic & Medicinal Chemistry Letters
  • Paramagnetic Chemical Probes for Studying Biological Macromolecules, 2022, Chemical Reviews
  • Paramagpy: software for fitting magnetic susceptibility tensors using paramagnetic effects measured in NMR spectra, 2020, Magnetic Resonance
  • Altered conformational sampling along an evolutionary trajectory changes the catalytic activity of an enzyme, 2020, Nature Communications
  • Antiviral cyclic peptides targeting the main protease of SARS-CoV-2, 2022, Chemical Science

Frequent coauthors of Gottfried Otting include:

  • Elwy H. Abdelkader
  • Thomas Huber
  • Haocheng Qianzhu
  • Colin J. Jackson
  • Christoph Nitsche

Publication venues where the scientist has most frequently published their work include:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Magnetic Resonance
  • Zenodo (CERN European Organization for Nuclear Research)
  • Journal of the American Chemical Society
  • bioRxiv (Cold Spring Harbor Laboratory)

Gottfried Otting was awarded the Australian Laureate Fellow in 2017.

Best Publications

  • Clean TOCSY for proton spin system identification in macromolecules

    C. Griesinger;G. Otting;K. Wuethrich;Richard R. Ernst

  • Homeodomain-DNA recognition

    Walter J. Gehring;Yan Qiu Qian;Martin Billeter;Katsuo Furukubo-Tokunaga

  • Protein hydration in aqueous solution.

    Gottfried Otting;Edvards Liepinsh;Kurt Wüthrich

  • Stereospecific nuclear magnetic resonance assignments of the methyl groups of valine and leucine in the DNA-binding domain of the 434 repressor by biosynthetically directed fractional 13C labeling.

    Dario Neri;Thomas Szyperski;Gottfried Otting;Hans Senn

  • Alignment of Biological Macromolecules in Novel Nonionic Liquid Crystalline Media for NMR Experiments

    Markus Rückert and;Gottfried Otting

  • The structure of the Antennapedia homeodomain determined by NMR spectroscopy in solution: comparison with prokaryotic repressors.

    Y.Q. Qian;M. Billeter;G. Otting;M. Müller

  • Protein--DNA contacts in the structure of a homeodomain--DNA complex determined by nuclear magnetic resonance spectroscopy in solution.

    G. Otting;Yan Qiu Qian;M. Billeter;M. Müller

  • Origin of τ2 and τ2 ridges in 2D NMR spectra and procedures for suppression

    Gottfried Otting;Hans Widmer;Gerhard Wagner;Kurt Wüthrich

  • Heteronuclear filters in two-dimensional [1H,1H] - NMR spectroscopy: combined use with isotope labelling for studies of macromolecular conformation and intermolecular interactions

    Gottfried Otting;Kurt Wüthrich

  • Studies of protein hydration in aqueous solution by direct NMR observation of individual protein-bound water molecules

    Gottfried Otting;Kurt Wuethrich

  • Solvent suppression using a spin lock in 2D and 3D NMR spectroscopy with H2O solutions

    Barbara A Messerle;Gerhard Wider;Gottfried Otting;Christoph Weber

  • Protein NMR Using Paramagnetic Ions

    Gottfried Otting

  • NMR structure of the death domain of the p75 neurotrophin receptor.

    Edvards Liepinsh;Leopold L. Ilag;Gottfried Otting;Carlos F. Ibáñez

  • Proton exchange rates from amino acid side chains--implications for image contrast.

    Edvards Liepinsh;Gottfried Otting

  • Determination of the nuclear magnetic resonance solution structure of an Antennapedia homeodomain-DNA complex.

    Martin Billeter;Yan Qiu Qian;Gottfried Otting;Martin Müller

  • NMR structure determination of protein - ligand complexes by lanthanide labeling

    Guido Pintacuda;Michael John;Xun-Cheng Su;Gottfried Otting

  • The structure of the homeodomain and its functional implications.

    W.J. Gehring;M. Müller;M. Affolter;A. Percival-Smith

  • NMR observation of individual molecules of hydration water bound to DNA duplexes: direct evidence for a spine of hydration water present in aqueous solution

    Edvards Liepinsh;Gottfried Otting;Kurt Wüthrich

  • Saposin fold revealed by the NMR structure of NK-lysin

    Edvards Liepinsh;Mats Andersson;Jean-Marie Ruysschaert;Gottfried Otting

  • Hydration of proteins. A comparison of experimental residence times of water molecules solvating the bovine pancreatic trypsin inhibitor with theoretical model calculations

    R.M. Brunne;E. Liepinsh;G. Otting;K. Wüthrich

  • NMR studies of water bound to biological molecules

    Gottfried Otting

Frequent Co-Authors

Nicholas E. Dixon
Nicholas E. Dixon University of Wollongong
Kurt Wüthrich
Kurt Wüthrich ETH Zurich
Thomas Huber
Thomas Huber Australian National University
Xun-Cheng Su
Xun-Cheng Su Nankai University
Guido Pintacuda
Guido Pintacuda École Normale Supérieure de Lyon
Daniella Goldfarb
Daniella Goldfarb Weizmann Institute of Science
Martin Billeter
Martin Billeter University of Gothenburg
Walter J. Gehring
Walter J. Gehring University of Basel
Markus Affolter
Markus Affolter University of Basel
Siew Pheng Lim
Siew Pheng Lim A*STAR - Agency for Science, Technology and Research

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