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Molecular Biology

D-Index
82
Citations
20692
World Ranking
942
National Ranking
15

Overview

Markus Affolter is affiliated with the University of Basel in Switzerland. Their research primarily focuses on Biochemistry, Genetics, and Molecular Biology, with significant contributions to Molecular Biology, Cell Biology, Genetics, Radiology, Nuclear Medicine and Imaging, and Plant Science.

The scientist's work covers several main topics, including:

  • Hippo pathway signaling and YAP/TAZ
  • Zebrafish Biomedical Research Applications
  • Developmental Biology and Gene Regulation
  • Cellular Mechanics and Interactions
  • Angiogenesis and VEGF in Cancer
  • Monoclonal and Polyclonal Antibodies Research
  • RNA and protein synthesis mechanisms

Markus Affolter has published extensively, with a range of recent papers demonstrating ongoing research activity. Notable publications include:

  • "Regulation of BMP4/Dpp retrotranslocation and signaling by deglycosylation," 2020, eLife
  • "Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc," 2021, Nature Communications
  • "Protein manipulation using single copies of short peptide tags in cultured cells and in Drosophila melanogaster," 2021, Development
  • "Vinculin controls endothelial cell junction dynamics during vascular lumen formation," 2022, Cell Reports
  • "Heterodimerization-dependent secretion of bone morphogenetic proteins in Drosophila," 2023, Developmental Cell

The scientist frequently collaborates with other researchers, with the most frequent coauthors being Gustavo Aguilar, Heinz-Georg Belting, Shinya Matsuda, Maria P. Kotini, and M Viganò.

In terms of publication venues, Markus Affolter's work appears most often in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Development
  • Developmental Cell
  • Current Topics in Developmental Biology

Best Publications

  • Homeodomain-DNA recognition

    Walter J. Gehring;Yan Qiu Qian;Martin Billeter;Katsuo Furukubo-Tokunaga

  • Structural basis of BMP signalling inhibition by the cystine knot protein Noggin

    Jay Groppe;Jason Greenwald;Ezra Wiater;Joaquin Rodriguez-Leon

  • Protein--DNA contacts in the structure of a homeodomain--DNA complex determined by nuclear magnetic resonance spectroscopy in solution.

    G. Otting;Yan Qiu Qian;M. Billeter;M. Müller

  • Fluorescent fusion protein knockout mediated by anti-GFP nanobody

    Emmanuel Caussinus;Oguz Kanca;Markus Affolter

  • Hox proteins meet more partners

    Richard S Mann;Markus Affolter

  • The Decapentaplegic morphogen gradient: from pattern formation to growth regulation.

    Markus Affolter;Konrad Basler

  • Homeodomain proteins: an update.

    Thomas R. Bürglin;Markus Affolter

  • An absolute requirement for both the type II and type I receptors, punt and thick veins, for Dpp signaling in vivo

    Esther Ruberte;Thomas Marty;Denise Nellen;Markus Affolter

  • Complex cell rearrangements during intersegmental vessel sprouting and vessel fusion in the zebrafish embryo

    Yannick Blum;Heinz-Georg Belting;Elin Ellertsdottir;Lukas Herwig

  • Receptor serine/threonine kinases implicated in the control of Drosophila body pattern by decapentaplegic

    Denise Nellen;Markus Affolter;Konrad Basler

  • Tube or not tube : remodeling epithelial tissues by branching morphogenesis

    Markus Affolter;Savério Bellusci;Nobuyuki Itoh;Benny Shilo

  • The structure of the homeodomain and its functional implications.

    W.J. Gehring;M. Müller;M. Affolter;A. Percival-Smith

  • Regulation of Hox target genes by a DNA bound Homothorax/Hox/Extradenticle complex.

    Hyung Don Ryoo;Thomas Marty;Fernando Casares;Markus Affolter

  • Flow-Dependent Endothelial YAP Regulation Contributes to Vessel Maintenance

    Hiroyuki Nakajima;Kimiko Yamamoto;Sobhika Agarwala;Kenta Terai

  • Isolation and sequence-specific DNA binding of the Antennapedia homeodomain.

    M Müller;M Affolter;W Leupin;G Otting

  • Distinct Cellular Mechanisms of Blood Vessel Fusion in the Zebrafish Embryo

    Lukas Herwig;Yannick Blum;Alice Krudewig;Elin Ellertsdottir

  • DNA binding properties of the purified Antennapedia homeodomain.

    Markus Affolter;Anthony Percival-Smith;Martin Muller;Werner Leupin

  • Conversion of an Extracellular Dpp/BMP Morphogen Gradient into an Inverse Transcriptional Gradient

    Bruno Müller;Britta Hartmann;George Pyrowolakis;Markus Affolter

  • Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway

    Benjamin Kleaveland;Xiangjian Zheng;Jian J Liu;Yannick Blum

  • The Drosophila Protein Dof Is Specifically Required for FGF Signaling

    Stéphane Vincent;Robert Wilson;Carmen Coelho;Markus Affolter

Frequent Co-Authors

Walter J. Gehring
Walter J. Gehring University of Basel
Konrad Basler
Konrad Basler University of Zurich
Kurt Wüthrich
Kurt Wüthrich ETH Zurich
Richard S. Mann
Richard S. Mann Columbia University
Paul Schedl
Paul Schedl Princeton University
Gottfried Otting
Gottfried Otting Australian National University
Maria Leptin
Maria Leptin University of Cologne
Martin Billeter
Martin Billeter University of Gothenburg
Alexander F. Schier
Alexander F. Schier University of Basel
Sven Bergmann
Sven Bergmann Swiss Institute of Bioinformatics

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