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D-Index & Metrics

Molecular Biology

D-Index
70
Citations
22248
World Ranking
1407
National Ranking
716

Research.com Recognitions

  • 2003 - Fellow of the American Academy of Arts and Sciences

Overview

Thomas B. Kornberg is a researcher affiliated with the University of California, San Francisco, United States. Their work is primarily situated within the broad field of Biochemistry, Genetics, and Molecular Biology, with specific contributions in several subfields including Molecular Biology, Cell Biology, Biophysics, Aging, and Insect Science.

The scientist's research covers varied topics associated with developmental and cellular processes. Key areas of focus include Developmental Biology and Gene Regulation, Wnt/β-catenin signaling in development and cancer, Hedgehog Signaling Pathway Studies, Hippo pathway signaling and YAP/TAZ, Genetics, Aging, and Longevity in Model Organisms, Cell Image Analysis Techniques, and Endoplasmic Reticulum Stress and Disease.

Thomas B. Kornberg has coauthored research with a number of frequent collaborators, including Guilherme Oliveira Barbosa, Ryo Hatori, Zhe Zhang, Meirong Bai, and Shuo Luo. These partnerships reflect interconnected research efforts across multiple projects in related fields.

Their publication record includes articles in a range of venues, including bioRxiv (Cold Spring Harbor Laboratory) where they have published five works, The Journal of Cell Biology and Development with two publications each, as well as notable contributions in Science and Nature Methods.

Among recent published papers, notable titles include:

  • Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly, 2022, Science
  • DaXi-high-resolution, large imaging volume and multi-view single-objective light-sheet microscopy, 2022, Nature Methods
  • Broadly conserved roles of TMEM131 family proteins in intracellular collagen assembly and secretory cargo trafficking, 2020, Science Advances
  • The conserved transmembrane protein TMEM-39 coordinates with COPII to promote collagen secretion and regulate ER stress response, 2021, PLoS Genetics
  • Metabolic control of progenitor cell propagation during Drosophila tracheal remodeling, 2022, Nature Communications

Thomas B. Kornberg has been recognized by the American Academy of Arts and Sciences, having received the title of Fellow in 2003.

Best Publications

  • Crystal structure of an engrailed homeodomain-DNA complex at 2.8 A resolution: a framework for understanding homeodomain-DNA interactions.

    Charles R. Kissinger;Beishan Liu;Enrique Martin-Blanco;Thomas B. Kornberg

  • Expression of engrailed proteins in arthropods, annelids, and chordates

    Nipam H. Patel;Enrique Martin-Blanco;Kevin G. Coleman;Stephen J. Poole

  • Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor.

    Pedro Aza-Blanc;Felipe-Andrés Ramírez-Weber;Marie-Pierre Laget;Carol Schwartz

  • Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs

    Tetsuya Tabata;Thomas B. Kornberg

  • Cytonemes: Cellular Processes that Project to the Principal Signaling Center in Drosophila Imaginal Discs

    Felipe-Andrés Ramírez-Weber;Thomas B Kornberg

  • The engrailed locus of drosophila: Structural analysis of an embryonic transcript

    Stephen J. Poole;Lawrence M. Kauvar;Barry Drees;Thomas Kornberg

  • Daughters against dpp modulates dpp organizing activity in Drosophila wing development

    Kazuhide Tsuneizumi;Takuya Nakayama;Takuya Nakayama;Yuko Kamoshida;Thomas B. Kornberg;Thomas B. Kornberg

  • The Drosophila hedgehog gene is expressed specifically in posterior compartment cells and is a target of engrailed regulation.

    T Tabata;S Eaton;T B Kornberg

  • The engrailed locus of drosophila: In situ localization of transcripts reveals compartment-specific expression

    Thomas Kornberg;Inga Sidén;Patrick O'Farrell;Michael Simon

  • A DNA-unwinding protein isolated from Escherichia coli: its interaction with DNA and with DNA polymerases.

    Nolan Sigal;Hajo Delius;Thomas Kornberg;Malcolm L. Gefter

  • Expression of engrailed during segmentation in grasshopper and crayfish

    N.H. Patel;T.B. Kornberg;C.S. Goodman

  • Analysis of DNA Polymerases II and III in Mutants of Escherichia coli Thermosensitive for DNA Synthesis

    Malcolm L. Gefter;Yukinori Hirota;Thomas Kornberg;James A. Wechsler

  • Engrailed: a gene controlling compartment and segment formation in Drosophila.

    Thomas Kornberg

  • Creating a Drosophila wing de novo, the role of engrailed, and the compartment border hypothesis

    Tetsuya Tabata;Carol Schwartz;Elizabeth Gustavson;Zehra Ali

  • In vitro transcription of the Drosophila engrailed gene.

    Walter C. Soeller;Stephen J. Poole;Thomas Kornberg

  • Region-specific recombination and expression are directed by portions of the Drosophila engrailed promoter.

    C Hama;Z Ali;T B Kornberg

  • FGF is an essential mitogen and chemoattractant for the air sacs of the drosophila tracheal system.

    Makoto Sato;Thomas B. Kornberg

  • Expression of the vertebrate Gli proteins in Drosophila reveals a distribution of activator and repressor activities.

    P. Aza-Blanc;H.Y. Lin;A. Ruiz i Altaba;T.B. Kornberg

  • Expression during embryogenesis of a mouse gene with sequence homology to the Drosophila engrailed gene

    Alexandra L. Joyner;Thomas Kornberg;Kevin G. Coleman;David R. Cox

  • Dependence of Drosophila wing imaginal disc cytonemes on Decapentaplegic

    Frank Hsiung;Felipe-Andrès Ramirez-Weber;Felipe-Andrès Ramirez-Weber;D. David Iwaki;Thomas B. Kornberg

Frequent Co-Authors

J. Michael Bishop
J. Michael Bishop University of California, San Francisco
Dean Sheppard
Dean Sheppard University of California, San Francisco
Suzanne Eaton
Suzanne Eaton Max Planck Society
Shaun R. Coughlin
Shaun R. Coughlin University of California, San Francisco
Nipam H. Patel
Nipam H. Patel Marine Biological Laboratory
Mark Terasaki
Mark Terasaki University of Connecticut Health Center
Yuh Nung Jan
Yuh Nung Jan University of California, San Francisco
Akiko Hata
Akiko Hata University of California, San Francisco
Richard D. Fetter
Richard D. Fetter University of California, San Francisco

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