World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
75
Citations
26848
World Ranking
1883
National Ranking
865

Molecular Biology

D-Index
75
Citations
26848
World Ranking
1177
National Ranking
608

Research.com Recognitions

  • 2008 - Member of the National Academy of Sciences
  • 2005 - Fellow of the American Academy of Arts and Sciences
  • 1987 - Fellow of Alfred P. Sloan Foundation

Overview

Gary Struhl is affiliated with Columbia University in the United States and specializes in Biochemistry, Genetics, and Molecular Biology, with a focus on Molecular Biology, Cell Biology, and Aging. Their research covers main topics including Developmental Biology and Gene Regulation, Retinal Development and Disorders, Hippo pathway signaling and YAP/TAZ, Genetics, Aging, and Longevity in Model Organisms, Epigenetics and DNA Methylation, Pluripotent Stem Cells Research, and Neurobiology and Insect Physiology Research.

Their recent papers include:

  • Control of Drosophila wing size by morphogen range and hormonal gating (2020), Proceedings of the National Academy of Sciences
  • A unified mechanism for the control of Drosophila wing growth by the morphogens Decapentaplegic and Wingless (2021), PLoS Biology
  • Evolutionary plasticity in the requirement for force exerted by ligand endocytosis to activate C. elegans Notch proteins (2022), Current Biology
  • The C. elegans Notch proteins LIN-12 and GLP-1 are tuned to lower force thresholds for activation than Drosophila Notch (2021), bioRxiv (Cold Spring Harbor Laboratory)
  • Context-dependent transcriptional regulation by Drosophila Polycomb Response Elements (2022), bioRxiv (Cold Spring Harbor Laboratory)

Frequent co-authors of Gary Struhl are:

  • Paul D. Langridge
  • Iva Greenwald
  • Jessica Yu Chan
  • Frederick C. Baker
  • J G Harman

Their work has been published in several venues, notably:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • PLoS Biology
  • Current Biology
  • Genetics

Gary Struhl has received recognition including:

  • Member of the National Academy of Sciences, 2008
  • Fellow of the American Academy of Arts and Sciences, 2005
  • Fellow of Alfred P. Sloan Foundation, 1987

Best Publications

  • Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

    Jin Jiang;Gary Struhl

  • Compartment boundaries and the control of Drosophila limb pattern by hedgehog protein.

    Konrad Basler;Gary Struhl

  • Dual Roles for Patched in Sequestering and Transducing Hedgehog

    Yu Chen;Gary Struhl

  • Direct and long-range action of a DPP morphogen gradient.

    Denise Nellen;Richard Burke;Gary Struhl;Konrad Basler

  • Presenilin is required for activity and nuclear access of Notch in Drosophila

    Gary Struhl;Iva Greenwald

  • Organizing activity of wingless protein in Drosophila.

    Gary Struhl;Konrad Basler

  • Nuclear Access and Action of Notch In Vivo

    Gary Struhl;Atsuko Adachi

  • Direct and Long-Range Action of a Wingless Morphogen Gradient

    Myriam Zecca;Konrad Basler;Gary Struhl

  • The gradient morphogen bicoid is a concentration-dependent transcriptional activator

    Gary Struhl;Kevin Struhl;Paul M. Macdonald

  • MORPHOGENS, COMPARTMENTS, AND PATTERN : LESSONS FROM DROSOPHILA ?

    Peter A Lawrence;Gary Struhl

  • Sequential organizing activities of engrailed, hedgehog and decapentaplegic in the Drosophila wing

    Zecca M;Basler K;Struhl G

  • Intrinsic activity of the lin-12 and Notch intracellular domains in vivo

    Gary Struhl;Kevin Fitzgerald;Kevin Fitzgerald;Iva Greenwald;Iva Greenwald

  • A molecular gradient in early Drosophila embryos and its role in specifying the body pattern

    Paul M. Macdonald;Gary Struhl;Gary Struhl

  • Requirements for Presenilin-Dependent Cleavage of Notch and Other Transmembrane Proteins

    Gary Struhl;Atsuko Adachi

  • RNA regulatory elements mediate control of Drosophila body pattern by the posterior morphogen nanos

    Robin P. Wharton;Gary Struhl

  • A hedgehog-insensitive form of patched provides evidence for direct long-range morphogen activity of sonic hedgehog in the neural tube.

    James Briscoe;Yu Chen;Yu Chen;Thomas M. Jessell;Gary Struhl

  • RNA recognition and translational regulation by a homeodomain protein

    Josh Dubnau;Gary Struhl

  • Genes controlling segmental specification in the Drosophila thorax

    Gary Struhl

  • Isolation, structure, and expression of even-skipped: A second pair-rule gene of Drosophila containing a homeo box

    Paul M. Macdonald;Phil Ingham;Gary Struhl

  • A gene product required for correct initiation of segmental determination in Drosophila

    Gary Struhl

Frequent Co-Authors

Peter A. Lawrence
Peter A. Lawrence University of Cambridge
Iva Greenwald
Iva Greenwald Columbia University
Konrad Basler
Konrad Basler University of Zurich
Ginés Morata
Ginés Morata Spanish National Research Council
Paul M. Macdonald
Paul M. Macdonald The University of Texas at Austin
Jin Jiang
Jin Jiang The University of Texas Southwestern Medical Center
James Briscoe
James Briscoe The Francis Crick Institute
Yu Chen
Yu Chen New York University
Kevin Struhl
Kevin Struhl Harvard University
Claude Desplan
Claude Desplan New York University

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