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Biology and Biochemistry

D-Index
57
Citations
10106
World Ranking
13986
National Ranking
1099

Overview

Jean-Paul Vincent is affiliated with The Francis Crick Institute in the United Kingdom and has a research focus within the fields of biochemistry, genetics, and molecular biology. Their work prominently intersects with molecular and cell biology, as well as cellular and molecular neuroscience, immunology, and insect science.

The scientist's research covers topics such as:

  • Wnt/β-catenin signaling in development and cancer
  • Neurobiology and insect physiology research
  • Invertebrate immune response mechanisms
  • Cancer-related gene regulation
  • Developmental biology and gene regulation
  • Insect symbiosis and bacterial influences
  • Hippo pathway signaling and YAP/TAZ

Recent publications illustrate the scope and impact of their work. Notable papers include:

  • "NOTUM from Apc-mutant cells biases clonal competition to initiate cancer," 2021, Nature
  • "Glypicans shield the Wnt lipid moiety to enable signalling at a distance," 2020, Nature
  • "Generation of extracellular morphogen gradients: the case for diffusion," 2021, Nature Reviews Genetics
  • "Patterning and growth control in vivo by an engineered GFP gradient," 2020, Science
  • "Ribosomopathy-associated mutations cause proteotoxic stress that is alleviated by TOR inhibition," 2021, Nature Cell Biology

Jean-Paul Vincent frequently collaborates with several researchers, including Cyrille Alexandre, Guillaume Salbreux, E. Yvonne Jones, Nicky J. Willis, and Paul V. Fish.

Publication venues commonly featuring their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Developmental Cell
  • Journal of Medicinal Chemistry
  • Wellcome Open Research
  • Nature

Best Publications

  • Uncoupling cadherin-based adhesion from wingless signalling in Drosophila.

    Bénédicte Sanson;Phoebe White;Jean-Paul Vincent

  • Notum Deacylates Wnt Proteins to Suppress Signalling Activity.

    Satoshi Kakugawa;Paul F. Langton;Matthias Zebisch;Steven A. Howell

  • ESCRTs and Fab1 Regulate Distinct Steps of Autophagy

    Tor Erik Rusten;Thomas Vaccari;Karine Lindmo;Lina M W Rodahl

  • Characterization of the interface between normal and transformed epithelial cells.

    Catherine Hogan;Sophie Dupré-Crochet;Sophie Dupré-Crochet;Mark Norman;Mihoko Kajita

  • Patterning and growth control by membrane-tethered Wingless.

    Cyrille Alexandre;Alberto Baena-Lopez;Jean-Paul Vincent

  • Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex.

    Xavier Franch-Marro;Franz Wendler;Sonia Guidato;Janice Griffith

  • Regulated endocytic routing modulates wingless signaling in Drosophila embryos.

    Laurence Dubois;Magalie Lecourtois;Cyrille Alexandre;Elisabeth Hirst

  • Kinematics of gray crescent formation in Xenopus eggs: The displacement of subcortical cytoplasm relative to the egg surface☆

    Jean-Paul Vincent;George F. Oster;John C. Gerhart

  • Specification of the wing by localized expression of wingless protein

    Medard Ng;Fernando J. Diaz-Benjumea;Jean-Paul Vincent;Jun Wu

  • Segmentation and specification of the Drosophila mesoderm.

    Natalia Azpiazu;Peter A. Lawrence;Jean-Paul Vincent;Manfred Frasch

  • Accelerated homologous recombination and subsequent genome modification in Drosophila

    Luis Alberto Baena-Lopez;Cyrille Alexandre;Alice Mitchell;Laurynas Pasakarnis

  • Subcortical rotation in Xenopus eggs: An early step in embryonic axis specification☆

    Jean-Paul Vincent;John C. Gerhart

  • The state of engrailed expression is not clonally transmitted during early Drosophila development

    Jean-Paul Vincent;Patrick H. O'Farrell

  • Exosomes in developmental signalling.

    Ian John McGough;Jean-Paul Vincent

  • Drosophila S2 Cells Secrete Wingless on Exosome-Like Vesicles but the Wingless Gradient Forms Independently of Exosomes

    Karen Beckett;Solange Monier;Lucy Palmer;Cyrille Alexandre

  • A fluorescent reporter of caspase activity for live imaging.

    Pierre-Luc Bardet;Golnar Kolahgar;Anita Mynett;Irene Miguel-Aliaga

  • Segmental patterning of heart precursors in Drosophila.

    Peter A. Lawrence;Rolf Bodmer;Jean-Paul Vincent

  • NOTUM from Apc-mutant cells biases clonal competition to initiate cancer.

    Dustin J. Flanagan;Nalle Pentinmikko;Kalle Luopajärvi;Nicky J. Willis

  • Glypicans shunt the Wingless signal between local signalling and further transport.

    Xavier Franch-Marro;Oriane Marchand;Eugenia Piddini;Sara Ricardo

  • Report ESCRTs and Fab1 Regulate Distinct Steps of Autophagy

    Tor Erik Rusten;Thomas Vaccari;Karine Lindmo;Ioannis P. Nezis

Frequent Co-Authors

Peter A. Lawrence
Peter A. Lawrence University of Cambridge
John C. Gerhart
John C. Gerhart University of California, Berkeley
James Briscoe
James Briscoe The Francis Crick Institute
Yohanns Bellaïche
Yohanns Bellaïche Institute Curie
Harald Alfred Stenmark
Harald Alfred Stenmark University of Oslo
Ambrosius P. Snijders
Ambrosius P. Snijders The Francis Crick Institute
Patrick H. O'Farrell
Patrick H. O'Farrell University of California, San Francisco
Andreas Brech
Andreas Brech Oslo University Hospital
George Oster
George Oster University of California, Berkeley
Konrad Basler
Konrad Basler University of Zurich

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