John C. Gerhart

Overview

Best Publications

• The Enzymology of Control by Feedback Inhibition

  John C. Gerhart;Arthur B. Pardee

  1417
  Citations

• Cells, embryos and evolution : toward a cellular and developmental understanding of phenotypic variation and evolutionary adaptability

  John C Gerhart;Marc W Kirschner;Eileen Starr Moderbacher

  1168
  Citations

• FORMATION AND FUNCTION OF SPEMANN'S ORGANIZER

  Richard Harland;John Gerhart

  971
  Citations

• Cell cycle dynamics of an M-phase-specific cytoplasmic factor in Xenopus laevis oocytes and eggs.

  J Gerhart;M Wu;M Kirschner

  769
  Citations

• Efficient construction of a large nonimmune phage antibody library: The production of high-affinity human single-chain antibodies to protein antigens

  Michael D. Sheets;Peter Amersdorfer;Ricarda Finnern;Peter Sargent

  740
  Citations

• Distinct Subunits for the Regulation and Catalytic Activity of Aspartate Transcarbamylase

  John C. Gerhart;Howard K. Schachman

  723
  Citations

• Cells, Embryos and Evolution

  John C. Gerhart;Marc Kirschner

  701
  Citations

• The Plausibility of Life: Resolving Darwin?s Dilemma

  Marc W. Kirschner;John C. Gerhart

  588
  Citations

• Cortical rotation of the Xenopus egg: consequences for the anteroposterior pattern of embryonic dorsal development.

  J. Gerhart;M. Danilchik;T. Doniach;S. Roberts

  576
  Citations

• The theory of facilitated variation

  John Gerhart;Marc Kirschner

  521
  Citations

• Anteroposterior Patterning in Hemichordates and the Origins of the Chordate Nervous System

  Christopher J Lowe;Mike Wu;Adrian Salic;Louise Evans

  516
  Citations

• The purification of aspartate transcarbamylase of Escherichia coli and separation of its protein subunits.

  John C. Gerhart;Hella Holoubek

  483
  Citations

• Allosteric Interactions in Aspartate Transcarbamylase. II. Evidence for Different Conformational States of the Protein in the Presence and Absence of Specific Ligands

  John C. Gerhart;Howard K. Schachman

  431
  Citations

• Early cellular interactions promote embryonic axis formation in Xenopus laevis.

  Robert L. Gimlich;John C. Gerhart

  373
  Citations

• Dorsoventral Patterning in Hemichordates: Insights into Early Chordate Evolution

  Christopher J Lowe;Mark Terasaki;Michael T. Wu;Robert M Freeman

  367
  Citations

• Changes in protein phosphorylation accompanying maturation of Xenopus laevis oocytes

  J. Maller;M. Wu;J.C. Gerhart

  353
  Citations

• Partial purification and characterization of the maturation-promoting factor from eggs of Xenopus laevis.

  Michael Wu;John C. Gerhart

  319
  Citations

• Allosteric interactions in aspartate transcarbamylase. I. Binding of specific ligands to the native enzyme and its isolated subunits.

  Jean P. Changeux;John C. Gerhart;Howard K. Schachman

  302
  Citations

• Determination of the dorsal-ventral axis in eggs of Xenopus laevis: complete rescue of uv-impaired eggs by oblique orientation before first cleavage.

  Stanley R. Scharf;John C. Gerhart

  292
  Citations

• Axis determination in eggs of Xenopus laevis: a critical period before first cleavage, identified by the common effects of cold, pressure and ultraviolet irradiation.

  Stanley R. Scharf;John C. Gerhart

  290
  Citations