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Douglas A. Melton

Douglas A. Melton

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Molecular Biology
USA
2026

D-Index & Metrics

Molecular Biology

D-Index
141
Citations
98161
World Ranking
116
National Ranking
77

Douglas A. Melton publication distribution in Molecular Biology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Molecular Biology in 2026. The highlighted bar marks where Douglas A. Melton sits on this spectrum.

47–56 publications: 7 scientists 57–66 publications: 17 scientists 67–76 publications: 65 scientists 77–86 publications: 90 scientists 87–96 publications: 125 scientists 97–106 publications: 131 scientists 107–116 publications: 162 scientists 117–126 publications: 177 scientists 127–136 publications: 158 scientists 137–146 publications: 158 scientists 147–156 publications: 146 scientists 157–166 publications: 159 scientists 167–176 publications: 131 scientists 177–186 publications: 110 scientists 187–196 publications: 112 scientists 197–206 publications: 100 scientists 207–216 publications: 89 scientists 217–226 publications: 98 scientists 227–236 publications: 74 scientists 237–246 publications: 72 scientists 247–256 publications: 63 scientists 257–266 publications: 53 scientists 267–276 publications: 54 scientists 277–286 publications: 49 scientists 287–296 publications: 52 scientists 297–306 publications: 43 scientists 307–316 publications: 46 scientists 317–326 publications: 41 scientists 327–336 publications: 42 scientists 337–346 publications: 31 scientists 347–356 publications: 28 scientists 357–366 publications: 29 scientists 367–376 publications: 26 scientists 377–386 publications: 24 scientists 387–396 publications: 24 scientists 397–406 publications: 14 scientists 407–416 publications: 13 scientists 417–426 publications: 20 scientists 427–436 publications: 12 scientists 437–446 publications: 20 scientists 447–456 publications: 11 scientists 457–466 publications: 10 scientists 467–476 publications: 14 scientists 477–486 publications: 14 scientists 487–496 publications: 10 scientists 497–506 publications: 13 scientists 507–516 publications: 13 scientists 517–526 publications: 2 scientists 527–536 publications: 4 scientists 537–546 publications: 6 scientists 547–556 publications: 8 scientists 557–563 publications: 6 scientists 564+ publications: 100 scientists
47 publications 564+

This scientist: 303 publications — 81st percentile

81% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 564 publications or more.

Douglas A. Melton D-index placement in Molecular Biology in 2026

The chart shows the D-index (discipline H-index) distribution of Molecular Biology scientists ranked by Research.com in 2026. The highlighted bar marks where Douglas A. Melton sits on this spectrum.

40–41 D-Index: 36 scientists 42–43 D-Index: 101 scientists 44–45 D-Index: 115 scientists 46–47 D-Index: 121 scientists 48–49 D-Index: 118 scientists 50–51 D-Index: 130 scientists 52–53 D-Index: 106 scientists 54–55 D-Index: 116 scientists 56–57 D-Index: 113 scientists 58–59 D-Index: 129 scientists 60–61 D-Index: 120 scientists 62–63 D-Index: 105 scientists 64–65 D-Index: 131 scientists 66–67 D-Index: 95 scientists 68–69 D-Index: 97 scientists 70–71 D-Index: 106 scientists 72–73 D-Index: 83 scientists 74–75 D-Index: 89 scientists 76–77 D-Index: 77 scientists 78–79 D-Index: 70 scientists 80–81 D-Index: 73 scientists 82–83 D-Index: 60 scientists 84–85 D-Index: 48 scientists 86–87 D-Index: 45 scientists 88–89 D-Index: 50 scientists 90–91 D-Index: 31 scientists 92–93 D-Index: 51 scientists 94–95 D-Index: 43 scientists 96–97 D-Index: 38 scientists 98–99 D-Index: 39 scientists 100–101 D-Index: 41 scientists 102–103 D-Index: 29 scientists 104–105 D-Index: 33 scientists 106–107 D-Index: 35 scientists 108–109 D-Index: 20 scientists 110–111 D-Index: 38 scientists 112–113 D-Index: 19 scientists 114–115 D-Index: 28 scientists 116–117 D-Index: 13 scientists 118–119 D-Index: 23 scientists 120–121 D-Index: 16 scientists 122–123 D-Index: 15 scientists 124–125 D-Index: 11 scientists 126–127 D-Index: 21 scientists 128–129 D-Index: 7 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 14 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 9 scientists 138–139 D-Index: 8 scientists 140–141 D-Index: 16 scientists 142–143 D-Index: 7 scientists 144 D-Index: 7 scientists 145+ D-Index: 100 scientists
40 D-Index 145+

This scientist: 141 D-Index — 96th percentile

96% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 145 D-Index or more.

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in United States Leader Award
  • 2025 - Research.com Molecular Biology in United States Leader Award
  • 2023 - Research.com Molecular Biology in United States Leader Award
  • 1995 - Fellow of the American Academy of Arts and Sciences
  • 1995 - Member of the National Academy of Sciences

Overview

Douglas A. Melton is affiliated with Harvard University in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Within these, they focus notably on Surgery, Molecular Biology, Genetics, Endocrinology, Diabetes and Metabolism, and Cell Biology.

Their main topics of study relate to Pancreatic function and diabetes, Diabetes and associated disorders, Diabetes Management and Research, Pluripotent Stem Cells Research, CRISPR and Genetic Engineering, Metabolism, Diabetes, and Cancer, as well as Genetics and Neurodevelopmental Disorders.

Recent publications include:

  • "A Nutrient-Sensing Transition at Birth Triggers Glucose-Responsive Insulin Secretion" (2020), published in Cell Metabolism
  • "Glucose Response by Stem Cell-Derived β Cells In Vitro Is Inhibited by a Bottleneck in Glycolysis" (2020), published in Cell Reports
  • "A method for the generation of human stem cell-derived alpha cells" (2020), published in Nature Communications
  • "Genome-scale in vivo CRISPR screen identifies RNLS as a target for beta cell protection in type 1 diabetes" (2020), published in Nature Metabolism
  • "The promise of stem cell-derived islet replacement therapy" (2021), published in Diabetologia

Common venues for publication include Diabetes, Transplantation, Cell Metabolism, Cell Reports, and Nature Communications.

Among frequent co-authors collaborating with Douglas A. Melton are Jennifer Hyoje-Ryu Kenty, Dario Gerace, Elad Sintov, Kyle R. Boulanger, and Aharon Helman.

Douglas A. Melton received recognition as a Fellow of the American Academy of Arts and Sciences as well as membership in the National Academy of Sciences, both awarded in 1995.

Best Publications

  • Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

    D.A. Melton;P.A. Krieg;M.R. Rebagliati;T. Maniatis

  • Core transcriptional regulatory circuitry in human embryonic stem cells.

    Laurie A. Boyer;Tong Ihn Lee;Megan F. Cole;Sarah E. Johnstone

  • A molecular mechanism for the effect of lithium on development

    Peter S. Klein;Douglas A. Melton

  • Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation.

    Yuval Dor;Juliana Brown;Olga I. Martinez;Douglas A. Melton

  • Control of developmental regulators by Polycomb in human embryonic stem cells.

    Tong Ihn Lee;Richard G. Jenner;Laurie A. Boyer;Matthew G. Guenther

  • In vivo reprogramming of adult pancreatic exocrine cells to beta-cells.

    Qiao Zhou;Juliana Brown;Andrew Kanarek;Jayaraj Rajagopal

  • Generation of functional human pancreatic β cells in vitro

    Felicia W. Pagliuca;Jeffrey R. Millman;Mads Gürtler;Michael Segel

  • "Stemness": Transcriptional Profiling of Embryonic and Adult Stem Cells

    Miguel Ramalho-Santos;Soonsang Yoon;Yumi Matsuzaki;Richard C. Mulligan

  • Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds

    Danwei Huangfu;René Maehr;Wenjun Guo;Astrid Eijkelenboom;Astrid Eijkelenboom

  • Functional messenger RNAs are produced by SP6 in vitro transcription of cloned cDNAs

    P.A. Krieg;D.A. Melton

  • Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2.

    Danwei Huangfu;Kenji Osafune;René Maehr;Wenjun Guo

  • Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors.

    Guoqiang Gu;Jolanta Dubauskaite;Douglas A. Melton

  • Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells

    Maya Schuldiner;Ofra Yanuka;Joseph Itskovitz-Eldor;Douglas A. Melton

  • Nuclear Reprogramming of Somatic Cells After Fusion with Human Embryonic Stem Cells

    Chad A. Cowan;Jocelyn Atienza;Douglas A. Melton;Kevin Eggan

  • A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure.

    Maayan Baron;Adrian Veres;Samuel L. Wolock;Aubrey L. Faust

  • Induction of Pancreatic Differentiation by Signals from Blood Vessels

    Eckhard Lammert;Ondine Cleaver;Douglas Melton

  • Derivation of embryonic stem-cell lines from human blastocysts.

    Chad A. Cowan;Irinha Klimanskaya;Jill Mcmahon;Jocelyn Atienza

  • Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity

    Ali Hemmati-Brivanlou;Olivia G. Kelly;Douglas A. Melton

  • Marked differences in differentiation propensity among human embryonic stem cell lines

    Kenji Osafune;Kenji Osafune;Leslie Caron;Malgorzata Borowiak;Malgorzata Borowiak;Rita J Martinez;Rita J Martinez

  • In vitro RNA synthesis with SP6 RNA polymerase.

    P A Krieg;D A Melton

Frequent Co-Authors

Ben Z. Stanger
Ben Z. Stanger University of Pennsylvania
Yuval Dor
Yuval Dor Hebrew University of Jerusalem
Chad A. Cowan
Chad A. Cowan Beth Israel Deaconess Medical Center
John M. Wozney
John M. Wozney Pfizer (Canada)
Vicki Rosen
Vicki Rosen Harvard University
Kevin Eggan
Kevin Eggan Harvard University
Sergei Y. Sokol
Sergei Y. Sokol Icahn School of Medicine at Mount Sinai
Matthias Hebrok
Matthias Hebrok University of California, San Francisco
Pardis C. Sabeti
Pardis C. Sabeti Harvard University

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