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John M. Wozney

John M. Wozney

D-Index & Metrics

Medicine

D-Index
113
Citations
53824
World Ranking
4901
National Ranking
190

Overview

John M. Wozney is affiliated with Pfizer in Canada and focuses their research primarily in the field of Medicine. Their work spans several subfields including Surgery, Pathology and Forensic Medicine, Rheumatology, and Urology.

Their research topics cover a range of areas related to musculoskeletal health and treatment methodologies. These topics include:

  • Spine and Intervertebral Disc Pathology
  • Orthopaedic implants and arthroplasty
  • Spinal Fractures and Fixation Techniques
  • Osteoarthritis Treatment and Mechanisms
  • Periodontal Regeneration and Treatments
  • Hip disorders and treatments

Wozney has published work predominantly in the Journal of Bone and Joint Surgery. Two of their recent papers, which illustrate their research interests and collaborations, are:

  • "A BMP/Activin A Chimera Induces Posterolateral Spine Fusion in Nonhuman Primates at Lower Concentrations Than BMP-2," published in 2021 in the Journal of Bone and Joint Surgery
  • "Activation of Bone Remodeling Compartments in BMP-2-Injected Knees Supports a Local Vascular Mechanism for Arthritis-Related Bone Changes," published in 2020 in the Journal of Bone and Joint Surgery

The scientist frequently collaborates with several co-authors, reflecting interdisciplinary and cooperative research approaches. Notable co-authors include:

  • Howard Seeherman
  • Christopher G. Wilson
  • Eric J. Vanderploeg
  • Christopher Brown
  • Pablo Morales

Wozney's portfolio indicates a focused engagement with clinical and therapeutic aspects of orthopaedics and related medical interventions. Their contributions center around understanding bone remodeling, spinal conditions, and treatment options potentially involving biomolecular therapies such as BMP-related compounds.

Best Publications

  • Novel Regulators of Bone Formation: Molecular Clones and Activities

    John M. Wozney;Vicki Rosen;Anthony J. Celeste;Lisa M. Mitsock

  • Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage.

    T Katagiri;A Yamaguchi;M Komaki;E Abe

  • Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone

    Anthony J. Celeste;James A. Iannazzi;Robin C. Taylor;Rodney M. Hewick

  • Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12.

    Kyeong-Sook Lee;Hyun-Jung Kim;Qing-Lin Li;Xin-Zi Chi

  • Molecular cloning of a cDNA encoding human antihaemophilic factor.

    Toole Jj;Knopf Jl;Wozney Jm;Sultzman La

  • THE HEALING OF SEGMENTAL BONE DEFECTS, INDUCED BY RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN (rhBMP‐2): A RADIOGRAPHIC, HISTOLOGICAL, AND BIOMECHANICAL STUDY IN RATS

    AW Yasko;JM Lane;EJ Fellinger;V. Rosen

  • The bone morphogenetic protein family and osteogenesis.

    John M. Wozney

  • Purification and characterization of other distinct bone-inducing factors

    Elizabeth A. Wang;Vicki Rosen;Paul Cordes;Rodney M. Hewick

  • Recombinant human bone morphogenetic protein-2 stimulates osteoblastic maturation and inhibits myogenic differentiation in vitro.

    A Yamaguchi;T Katagiri;T Ikeda;J M Wozney

  • Bone morphogenetic protein and bone morphogenetic protein gene family in bone formation and repair.

    John M. Wozney;Vicki Rosen

  • Transforming Growth Factor-β Gene Family Members and Bone*

    Michael Centrella;Mark C. Horowitz;John M. Wozney;Thomas L. Mccarthy

  • The non-osteogenic mouse pluripotent cell line, C3H10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenetic protein-2.

    Takenobu Katagiri;Akira Yamaguchi;Tohru Ikeda;Shusaku Yoshiki

  • A Phase I/II trial of MYO-029 in Adult Subjects with Muscular Dystrophy

    Kathryn R. Wagner;James L. Fleckenstein;Anthony A. Amato;Richard J. Barohn

  • Overview of bone morphogenetic proteins.

    John M Wozney

  • BMP-2-induced Osterix expression is mediated by Dlx5 but is independent of Runx2.

    Mi-Hye Lee;Tae-Geon Kwon;Hyo-Sang Park;John M Wozney

  • Delivery of bone morphogenetic proteins for orthopedic tissue regeneration.

    Howard Seeherman;John M. Wozney

  • BMP-2-induced Runx2 Expression Is Mediated by Dlx5, and TGF-β1 Opposes the BMP-2-induced Osteoblast Differentiation by Suppression of Dlx5 Expression

    Mi-Hye Lee;Youn-Jeong Kim;Hyun-Jung Kim;Hyun-Dong Park

  • Effects of transforming growth factor β on bone nodule formation and expression of bone morphogenetic protein 2, osteocalcin, osteopontin, alkaline phosphatase, and type I collagen mRNA in long-term cultures of fetal rat calvarial osteoblasts

    S. E. Harris;Lynda Bonewald;M. A. Harris;M. Sabatini

  • Heterodimeric Bone Morphogenetic Proteins Show Enhanced Activity In Vitro and In Vivo

    David I. Israel;John Nove;Kelvin M. Kerns;Randal J. Kaufman

  • EXPRESSION PATTERNS OF BONE MORPHOGENETIC PROTEINS (BMPS) IN THE DEVELOPING MOUSE TOOTH SUGGEST ROLES IN MORPHOGENESIS AND CELL DIFFERENTIATION

    Thomas Åberg;John Wozney;Irma Thesleff

Frequent Co-Authors

Vicki Rosen
Vicki Rosen Harvard University
Scott A. Rodeo
Scott A. Rodeo Hospital for Special Surgery
Debra D. Pittman
Debra D. Pittman Pfizer (United States)
Joseph M. Lane
Joseph M. Lane Hospital for Special Surgery
Douglas A. Melton
Douglas A. Melton Harvard University
Hasan Uludağ
Hasan Uludağ University of Alberta
Randal J. Kaufman
Randal J. Kaufman Sanford Burnham Prebys Medical Discovery Institute
Mary L. Bouxsein
Mary L. Bouxsein Beth Israel Deaconess Medical Center
Alnawaz Rehemtulla
Alnawaz Rehemtulla University of Michigan–Ann Arbor
Scott D. Boden
Scott D. Boden Emory University

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