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Medicine

D-Index
81
Citations
24275
World Ranking
16643
National Ranking
8353

Research.com Recognitions

  • 2009 - Member of the National Academy of Medicine (NAM)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Frederick S. Kaplan is affiliated with the University of Pennsylvania in the United States. Their research primarily focuses on medical aspects of heterotopic ossification and related conditions, with significant contributions to the understanding and treatment of fibrodysplasia ossificans progressiva (FOP).

Their recent published papers include the following:

  • Reduction of New Heterotopic Ossification (HO) in the Open-Label, Phase 3 MOVE Trial of Palovarotene for Fibrodysplasia Ossificans Progressiva (FOP), 2022, Journal of Bone and Mineral Research
  • Prevalence of fibrodysplasia ossificans progressiva (FOP) in the United States: estimate from three treatment centers and a patient organization, 2021, Orphanet Journal of Rare Diseases
  • Palovarotene for Fibrodysplasia Ossificans Progressiva (FOP): Results of a Randomized, Placebo-Controlled, Double-Blind Phase 2 Trial, 2020, Journal of Bone and Mineral Research
  • Fibrodysplasia Ossificans Progressiva (FOP): A Segmental Progeroid Syndrome, 2020, Frontiers in Endocrinology
  • Epidemiology of the Global Fibrodysplasia Ossificans Progressiva (FOP) Community, 2020, Journal of Rare Diseases Research & Treatment

Frederick S. Kaplan collaborates frequently with other researchers, including:

  • Robert J. Pignolo
  • Mona Al Mukaddam
  • Richard Keen
  • Edward C. Hsiao
  • Geneviève Baujat

The venues where Kaplan publishes most often include:

  • Journal of Bone and Mineral Research
  • Biomolecules
  • Value in Health
  • Bone
  • Journal of the Endocrine Society

Their work mainly falls under the field of Medicine, with more specific subfields including Rheumatology, Pulmonary and Respiratory Medicine, Nephrology, Genetics, and Molecular Biology.

Main topics of Kaplan's research encompass:

  • Heterotopic Ossification and Related Conditions
  • Medical Imaging and Pathology Studies
  • Parathyroid Disorders and Treatments
  • Bone Tumor Diagnosis and Treatments
  • Genetic Syndromes and Imprinting
  • Bone health and treatments
  • Renal and related cancers

Kaplan has been recognized by professional organizations, including membership in the National Academy of Medicine since 2009 and the Association of American Physicians.

Best Publications

  • Bone Formation and Inflammation in Cardiac Valves

    Emile R. Mohler;Francis Gannon;Carol Reynolds;Robert Zimmerman

  • A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva

    Eileen M Shore;Meiqi Xu;George J Feldman;David A Fenstermacher

  • Overexpression of an Osteogenic Morphogen in Fibrodysplasia Ossificans Progressiva

    Adam B. Shafritz;Eileen M. Shore;Francis H. Gannon;Michael A. Zasloff

  • Treatment of Osteoporosis: Are Physicians Missing an Opportunity?*†

    Kevin B. Freedman;Frederick S. Kaplan;Warren B. Bilker;Brian L. Strom

  • Classic and atypical fibrodysplasia ossificans progressiva (FOP) phenotypes are caused by mutations in the bone morphogenetic protein (BMP) type I receptor ACVR1.

    Frederick S. Kaplan;Meiqi Xu;Petra Seemann;J. Michael Connor

  • The natural history of heterotopic ossification in patients who have fibrodysplasia ossificans progressiva. A study of forty-four patients.

    Randolph B. Cohen;Gregory V. Hahn;Jeffrey A. Tabas;Jeannie Peeper

  • Fibrodysplasia ossificans progressiva

    Frederick S. Kaplan;Martine Le Merrer;David L. Glaser;Robert J. Pignolo

  • Identification of Progenitor Cells That Contribute to Heterotopic Skeletogenesis

    Vitali Y. Lounev;Rageshree Ramachandran;Michael N. Wosczyna;Masakazu Yamamoto

  • Osteoporosis. Definition and clinical presentation.

    David L. Glaser;Frederick S. Kaplan

  • Fibrodysplasia Ossificans Progressiva: Clinical and Genetic Aspects

    Robert J Pignolo;Eileen M Shore;Frederick S Kaplan

  • Paternally inherited inactivating mutations of the GNAS1 gene in progressive osseous heteroplasia.

    Eileen M. Shore;Jaimo Ahn;Suzanne Jan de Beur;Ming Li;Ming Li

  • Inherited human diseases of heterotopic bone formation.

    Eileen M. Shore;Frederick S. Kaplan

  • The Histopathology of Fibrodysplasia Ossificans Progressiva. An Endochondral Process.

    Frederick S. Kaplan;Jeffrey A. Tabas;Francis H. Gannon;Gerald Finkel

  • Age-related changes in proprioception and sensation of joint position.

    Frederick S. Kaplan;James E. Nixon;Mark Reitz;Lynne Rindfleish

  • Iatrogenic Harm Caused by Diagnostic Errors in Fibrodysplasia Ossificans Progressiva

    Joseph A. Kitterman;Sharon Kantanie;David M. Rocke;Frederick S. Kaplan

  • Severe osteoporosis in men

    Nicky Kelepouris;Kristine D. Harper;Francis Gannon;Frederick S. Kaplan

  • Progressive osseous heteroplasia

    Frederick S. Kaplan;Eileen M. Shore

  • Activation of Hedgehog signaling by loss of GNAS causes heterotopic ossification

    Jean B Regard;Deepti Malhotra;Jelena Gvozdenovic-Jeremic;Michelle Josey

  • The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization.

    Qi Shen;Shawn C. Little;Meiqi Xu;Julia Haupt

  • A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva

    E. M. Shore;M. Xu;G. J. Feldman;D. A. Fenstermacher

Frequent Co-Authors

Matthew A. Brown
Matthew A. Brown Guy's and St Thomas' NHS Foundation Trust
Maximilian Muenke
Maximilian Muenke American College of Medical Genetics
Emile R. Mohler
Emile R. Mohler University of Pennsylvania
Aris N. Economides
Aris N. Economides Regeneron (United States)
James T. Triffitt
James T. Triffitt University of Oxford
Warren B. Bilker
Warren B. Bilker University of Pennsylvania
Scott D. Boden
Scott D. Boden Emory University
Stephen G. Emerson
Stephen G. Emerson Columbia University
Brian L. Strom
Brian L. Strom Rutgers, The State University of New Jersey
Joel S. Karp
Joel S. Karp University of Pennsylvania

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