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Genetics

D-Index
67
Citations
16148
World Ranking
2532
National Ranking
1130

Overview

Wolf Dietrich Heyer is affiliated with the University of California, Davis in the United States. Their research primarily focuses on the field of Biochemistry, Genetics and Molecular Biology, with a strong emphasis on Molecular Biology. The scope of their work also extends into subfields such as Oncology, Plant Science, Cancer Research, and Genetics.

The scientist's research covers a range of molecular and genetic topics. Key topics of study include DNA Repair Mechanisms, CRISPR and Genetic Engineering, Photosynthetic Processes and Mechanisms, Chromosomal and Genetic Variations, Carcinogens and Genotoxicity Assessment, DNA and Nucleic Acid Chemistry, and PARP inhibition in cancer therapy.

Heyer has contributed to several recent publications of note. These include:

  • POLθ-mediated end joining is restricted by RAD52 and BRCA2 until the onset of mitosis, 2021, published in Nature Cell Biology
  • Guardians of the Genome: BRCA2 and Its Partners, 2021, published in Genes
  • DSS1 and ssDNA regulate oligomerization of BRCA2, 2020, published in Nucleic Acids Research
  • Rdh54/Tid1 inhibits Rad51-Rad54-mediated D-loop formation and limits D-loop length, 2020, published in eLife
  • Cancer testis antigens and genomic instability: More than immunology, 2021, published in DNA Repair

Their frequent collaborators include Aurèle Piazza, Jie Liu, Hang Phuong Le, Diedre Reitz, and Shih-Hsun Hung.

Publication venues where Heyer's work has appeared repeatedly include bioRxiv (Cold Spring Harbor Laboratory), Nucleic Acids Research, Nature Cell Biology, eLife, and the Journal of Visualized Experiments.

Best Publications

  • Regulation of homologous recombination in eukaryotes

    Wolf Dietrich Heyer;Kirk T. Ehmsen;Jie Liu

  • Homologous recombination in DNA repair and DNA damage tolerance

    Xuan Li;Wolf Dietrich Heyer

  • Homologous recombination and the repair of DNA Double-Strand Breaks

    William Douglass Wright;Shanaya Shital Shah;Wolf Dietrich Heyer

  • Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA

    Jie Liu;Tammy Doty;Tammy Doty;Bryan Gibson;Bryan Gibson;Wolf Dietrich Heyer

  • A mouse cytoplasmic exoribonuclease (mXRN1p) with preference for G4 tetraplex substrates

    Vladimir I. Bashkirov;Harry Scherthan;Jachen A. Solinger;Jean Marie Buerstedde

  • Alternate pathways involving Sgs1/Top3, Mus81/ Mms4, and Srs2 prevent formation of toxic recombination intermediates from single-stranded gaps created by DNA replication

    Francis Fabre;Allan Chan;Wolf Dietrich Heyer;Serge Gangloff

  • Damage Tolerance Protein Mus81 Associates with the FHA1 Domain of Checkpoint Kinase Cds1

    Michael N. Boddy;Antonia Lopez-Girona;Paul Shanahan;Heidrun Interthal

  • Rad54, a Swi2/Snf2-like Recombinational Repair Protein, Disassembles Rad51:dsDNA Filaments

    Jachen A. Solinger;Konstantin Kiianitsa;Wolf Dietrich Heyer

  • Rad54: the Swiss Army knife of homologous recombination?

    Wolf Dietrich Heyer;Xuan Li;Michael Rolfsmeier;Xiao Ping Zhang

  • MUS81 encodes a novel helix-hairpin-helix protein involved in the response to UV- and methylation-induced DNA damage in Saccharomyces cerevisiae.

    H. Interthal;W.-D. Heyer

  • Recombinational repair in yeast: Functional interactions between Rad51 and Rad54 proteins

    Beate Clever;Heidrun Interthal;Jacqueline Schmuckli-Maurer;Jeff King

  • Rad54 protein is targeted to pairing loci by the Rad51 nucleoprotein filament.

    Alexander V. Mazin;Carole J. Bornarth;Jachen A. Solinger;Wolf Dietrich Heyer

  • An essential Saccharomyces cerevisiae single-stranded DNA binding protein is homologous to the large subunit of human RP-A.

    Wolf Dietrich Heyer;Manchanahalli R S Rao;Lome F. Erdile;Thomas J. Kelly

  • Processing of joint molecule intermediates by structure-selective endonucleases during homologous recombination in eukaryotes

    Erin K. Schwartz;Wolf Dietrich Heyer

  • NADH-coupled microplate photometric assay for kinetic studies of ATP-hydrolyzing enzymes with low and high specific activities.

    Konstantin Kiianitsa;Jachen A. Solinger;Wolf Dietrich Heyer

  • DNA repair protein Rad55 is a terminal substrate of the DNA damage checkpoints.

    Vladimir I. Bashkirov;Jeff S. King;Elena V. Bashkirova;Jacqueline Schmuckli-Maurer

  • Rad51 paralogues Rad55-Rad57 balance the antirecombinase Srs2 in Rad51 filament formation.

    Jie Liu;Ludovic Renault;Xavier Veaute;Francis Fabre

  • Human and mouse homologs of the Saccharomyces cerevisiae RAD54 DNA repair gene: evidence for functional conservation

    Roland Kanaar;Christine Troelstra;Sigrid M A Swagemakers;Jeroen Essers

  • Characterization of a cDNA encoding the 70-kDa single-stranded DNA-binding subunit of human replication protein A and the role of the protein in DNA replication.

    L F Erdile;W D Heyer;R Kolodner;T J Kelly

  • DNA sequence analysis of the ade6 gene of Schizosaccharomyces pombe. Wild-type and mutant alleles including the recombination hot spot allele ade6-M26

    Philippe Szankasi;Wolf Dietrich Heyer;Peter Schuchert;Jürg Kohli

Frequent Co-Authors

Richard D. Kolodner
Richard D. Kolodner University of California, San Diego
Frédéric Chédin
Frédéric Chédin University of California, Davis
Stephen C. Kowalczykowski
Stephen C. Kowalczykowski University of California, Davis
Edward H. Egelman
Edward H. Egelman University of Virginia
Xiong Yu
Xiong Yu University of Virginia
Andrés Aguilera
Andrés Aguilera University of Seville
Dieter Söll
Dieter Söll Yale University
John R. Yates
John R. Yates Scripps Research Institute
Patrick Sung
Patrick Sung The University of Texas Health Science Center at San Antonio
Emmanuel Barillot
Emmanuel Barillot Institute Curie

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