World's Best Scientists 2026 revealed!
Lorraine S. Symington

Lorraine S. Symington

D-Index & Metrics

Genetics

D-Index
62
Citations
18628
World Ranking
2951
National Ranking
1291

Research.com Recognitions

  • 2020 - Member of the National Academy of Sciences
  • 2018 - Fellow of the American Academy of Arts and Sciences
  • 2009 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Lorraine S. Symington is affiliated with Columbia University in the United States and has contributed extensively to research in the field of Biochemistry, Genetics, and Molecular Biology. Their work spans a variety of subfields including Molecular Biology, Oncology, Cancer Research, Plant Science, and Cellular and Molecular Neuroscience.

The scientist's research primarily focuses on DNA repair mechanisms, with significant work also addressing CRISPR and genetic engineering, genomics and chromatin dynamics, PARP inhibition in cancer therapy, fungal and yeast genetics research, carcinogens and genotoxicity assessment, as well as DNA and nucleic acid chemistry.

Some notable recent papers authored or co-authored by Lorraine S. Symington include:

  • DNA End Resection: Mechanism and Control, 2021, Annual Review of Genetics
  • The Rad51 paralog complex Rad55-Rad57 acts as a molecular chaperone during homologous recombination, 2021, Molecular Cell
  • DNA end resection during homologous recombination, 2021, Current Opinion in Genetics & Development
  • The dark side of homology-directed repair, 2021, DNA Repair
  • Sequence and chromatin features guide DNA double-strand break resection initiation, 2023, Molecular Cell

Their frequent co-authors include Michael T. Kimble, M. J. Johnson, Léa Marie, Robert Gnügge, and Eric C. Greene. This indicates a collaborative approach involving several prominent researchers in related fields.

Lorraine S. Symington has published multiple articles in reputable venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Molecular Cell, eLife, and DNA Repair. The breadth of publication venues reflects the diversity and interdisciplinary nature of their work.

The scientist has been recognized with several awards, including:

  • Member of the National Academy of Sciences, 2020
  • Fellow of the American Academy of Arts and Sciences, 2018
  • Fellow of the American Association for the Advancement of Science (AAAS), 2009

Best Publications

  • Double-Strand Break End Resection and Repair Pathway Choice

    Lorraine S. Symington;Jean Gautier

  • Role of RAD52 Epistasis Group Genes in Homologous Recombination and Double-Strand Break Repair

    Lorraine S. Symington

  • Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing

    Eleni P. Mimitou;Lorraine S. Symington

  • Recombination proteins in yeast.

    Berit Olsen Krogh;Lorraine S. Symington

  • Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?

    Agnel Sfeir;Lorraine S. Symington

  • The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance.

    Sylvie Moreau;John R. Ferguson;Lorraine S. Symington

  • DNA end resection: many nucleases make light work.

    Eleni P. Mimitou;Lorraine S. Symington

  • Break-induced replication : What is it and what is it for?

    Bertrand Llorente;Catherine E. Smith;Lorraine S. Symington

  • Mechanism and regulation of DNA end resection in eukaryotes.

    Lorraine S. Symington

  • Template switching during break-induced replication

    Catherine E. Smith;Bertrand Llorente;Lorraine S. Symington

  • Mechanisms and Regulation of Mitotic Recombination in Saccharomyces cerevisiae

    Lorraine S. Symington;Rodney Rothstein;Michael Lisby

  • Ku prevents Exo1 and Sgs1‐dependent resection of DNA ends in the absence of a functional MRX complex or Sae2

    Eleni P Mimitou;Lorraine S Symington

  • Crystal structure of a Rad51 filament.

    Adam B Conway;Thomas W Lynch;Ying Zhang;Gary S Fortin;Gary S Fortin

  • End Resection at Double-Strand Breaks: Mechanism and Regulation

    Lorraine S. Symington

  • A Rad52 homolog is required for RAD51-independent mitotic recombination in Saccharomyces cerevisiae.

    Yun Bai;Lorraine S. Symington

  • RPA Coordinates DNA End Resection and Prevents Formation of DNA Hairpins

    Huan Chen;Michael Lisby;Lorraine S. Symington

  • Functional differences and interactions among the putative RecA homologs Rad51, Rad55, and Rad57.

    R D Johnson;L S Symington

  • Nucleases and helicases take center stage in homologous recombination

    Eleni P. Mimitou;Lorraine S. Symington

  • Exonuclease I of Saccharomyces cerevisiae functions in mitotic recombination in vivo and in vitro.

    P Fiorentini;K N Huang;D X Tishkoff;R D Kolodner

  • EXO1-A multi-tasking eukaryotic nuclease.

    Phuoc T. Tran;Naz Erdeniz;Lorraine S. Symington;R.Michael Liskay

Frequent Co-Authors

Thomas D. Petes
Thomas D. Petes Duke University
Rodney Rothstein
Rodney Rothstein Columbia University
Michael Lisby
Michael Lisby University of Copenhagen
Andrés Aguilera
Andrés Aguilera University of Seville
James E. Haber
James E. Haber Brandeis University
Richard D. Kolodner
Richard D. Kolodner University of California, San Diego
Hannah L. Klein
Hannah L. Klein New York University
Eric C. Greene
Eric C. Greene Columbia University
Ian D. Hickson
Ian D. Hickson University of Copenhagen
David J. Sherratt
David J. Sherratt University of Oxford

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring genetics opens the door to a wide range of online degrees and career opportunities. For those seeking roles in the healthcare industry, medical billing and coding online schools offer a practical route into health services management. This pathway allows you to engage in essential healthcare work without direct patient interaction.

If you wish to fast-track your education, you might consider enrolling in a fast track college degree. These programs are ideal for motivated learners who want to complete their studies more quickly and enter the workforce sooner.

Flexible schedules are increasingly important for many students. By choosing self paced degree programs, you can tailor your study and balance your academic commitments with work or family life.

Finally, many reputable institutions offer genetics-related courses through accredited online universities with no application fee, making it more accessible to start your educational journey. These diverse options ensure that different learners can find a pathway that fits their goals and circumstances.

Best Scientists Citing Lorraine S. Symington

Trending Scientists

Recently Published Articles