World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
52
Citations
12255
World Ranking
3781
National Ranking
1631

Overview

Eric C. Greene is affiliated with Columbia University in the United States and specializes in the field of Biochemistry, Genetics and Molecular Biology. Their research predominantly focuses on Molecular Biology, with considerable contributions in Oncology, Cancer Research, Cell Biology, and Genetics.

The scientist's main research topics encompass:

  • DNA Repair Mechanisms
  • CRISPR and Genetic Engineering
  • PARP inhibition in cancer therapy
  • DNA and Nucleic Acid Chemistry
  • Genomics and Chromatin Dynamics
  • Carcinogens and Genotoxicity Assessment
  • RNA and protein synthesis mechanisms

Eric C. Greene has authored numerous papers published in several high-impact venues. Frequent publication platforms include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Biological Chemistry
  • Science
  • Molecular Cell
  • Nature

Some recent notable publications are:

  • Computed structures of core eukaryotic protein complexes (2021, Science)
  • DNA Repair Pathway Choices in CRISPR-Cas9-Mediated Genome Editing (2021, Trends in Genetics)
  • Human Condensin I and II Drive Extensive ATP-Dependent Compaction of Nucleosome-Bound DNA (2020, Molecular Cell)
  • Rad54 Drives ATP Hydrolysis-Dependent DNA Sequence Alignment during Homologous Recombination (2020, Cell)
  • The Rad51 paralog complex Rad55-Rad57 acts as a molecular chaperone during homologous recombination (2021, Molecular Cell)

Collaboration is an integral aspect of their work, with frequent co-authors including:

  • Patrick Sung
  • Youngho Kwon
  • Upasana Roy
  • Aviv Meir
  • Vivek B. Raina

Best Publications

  • DNA interrogation by the CRISPR RNA-guided endonuclease Cas9

    Samuel H. Sternberg;Sy Redding;Martin Jinek;Eric C. Greene

  • Computed structures of core eukaryotic protein complexes.

    Ian R. Humphreys;Jimin Pei;Minkyung Baek;Aditya Krishnakumar

  • BRCA1–BARD1 promotes RAD51-mediated homologous DNA pairing

    Weixing Zhao;Justin B. Steinfeld;Fengshan Liang;Xiaoyong Chen

  • Visualizing one-dimensional diffusion of proteins along DNA.

    Jason Gorman;Eric C Greene

  • The condensin complex is a mechanochemical motor that translocates along DNA.

    Tsuyoshi Terakawa;Shveta Bisht;Jorine M. Eeftens;Cees Dekker

  • Dynamic Basis for One-Dimensional DNA Scanning by the Mismatch Repair Complex Msh2-Msh6

    Jason Gorman;Arindam Chowdhury;Jennifer A. Surtees;Jun Shimada

  • Concentration-Dependent Exchange of Replication Protein a on Single-Stranded DNA Revealed by Single-Molecule Imaging

    Bryan Gibb;Ling Feng Ye;Stephanie C. Gergoudis;YoungHo Kwon

  • Single-Molecule Imaging Reveals a Collapsed Conformational State for DNA-Bound Cohesin.

    Johannes Stigler;Gamze Ö. Çamdere;Douglas E. Koshland;Eric C. Greene

  • DNA Repair Pathway Choices in CRISPR-Cas9-Mediated Genome Editing.

    Chaoyou Xue;Eric C. Greene

  • RPA antagonizes microhomology-mediated repair of DNA double-strand breaks

    Sarah K Deng;Bryan Gibb;Mariana Justino de Almeida;Eric C Greene

  • Long-distance lateral diffusion of human Rad51 on double-stranded DNA.

    Annette Granéli;Caitlyn C. Yeykal;Ragan B. Robertson;Eric C. Greene

  • DNA sequence alignment by microhomology sampling during homologous recombination.

    Zhi Qi;Sy Redding;Ja Yil Lee;Bryan Gibb

  • Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System

    Sy Redding;Samuel H. Sternberg;Myles Marshall;Bryan Gibb

  • Visualizing one-dimensional diffusion of eukaryotic DNA repair factors along a chromatin lattice.

    Jason Gorman;Aaron J Plys;Mari-Liis Visnapuu;Eric Alani

  • Single-molecule imaging reveals target-search mechanisms during DNA mismatch repair.

    Jason Gorman;Feng Wang;Sy Redding;Aaron J. Plys

  • Single-molecule imaging reveals mechanisms of protein disruption by a DNA translocase

    Ilya J. Finkelstein;Mari Liis Visnapuu;Eric C. Greene

  • Base triplet stepping by the Rad51/RecA family of recombinases

    Ja Yil Lee;Tsuyoshi Terakawa;Tsuyoshi Terakawa;Zhi Qi;Justin B. Steinfeld

  • Organized arrays of individual DNA molecules tethered to supported lipid bilayers.

    Annette Graneli;Caitlyn C. Yeykal;Tekkatte Krishnamurthy Prasad;Eric C. Greene

  • Human Condensin I and II Drive Extensive ATP-Dependent Compaction of Nucleosome-Bound DNA

    Muwen Kong;Erin E. Cutts;Dongqing Pan;Fabienne Beuron

  • DNA Curtains and Nanoscale Curtain Rods: High-Throughput Tools for Single Molecule Imaging

    Teresa Fazio;Mari-Liis Visnapuu;Shalom Wind;Eric C. Greene

Frequent Co-Authors

Patrick Sung
Patrick Sung The University of Texas Health Science Center at San Antonio
Feng Wang
Feng Wang University of California, Berkeley
Eric Alani
Eric Alani Cornell University
Hannah L. Klein
Hannah L. Klein New York University
Lumir Krejci
Lumir Krejci Masaryk University
David J. Sherratt
David J. Sherratt University of Oxford
Jennifer A. Doudna
Jennifer A. Doudna University of California, Berkeley
Lorraine S. Symington
Lorraine S. Symington Columbia University
Simon J. Boulton
Simon J. Boulton The Francis Crick Institute
David R. Reichman
David R. Reichman Columbia University

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