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Biology and Biochemistry

D-Index
69
Citations
15481
World Ranking
7469
National Ranking
192

Overview

Gijs J. L. Wuite is a researcher affiliated with Vrije Universiteit Amsterdam in the Netherlands. Their scholarly contributions span the fields of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology, Atomic and Molecular Physics and Optics, Cell Biology, Biomedical Engineering, and Ecology.

Their research addresses key scientific topics including DNA and Nucleic Acid Chemistry, Bacteriophages and microbial interactions, Genomics and Chromatin Dynamics, Force Microscopy Techniques and Applications, Microtubule and mitosis dynamics, Microfluidic and Bio-sensing Technologies, and Advanced biosensing and bioanalysis techniques.

Among their recent publications are:

  • Physics of viral dynamics, 2021, Nature Reviews Physics
  • Mechanical Characterization of Liposomes and Extracellular Vesicles, a Protocol, 2020, Frontiers in Molecular Biosciences
  • 20S proteasomes secreted by the malaria parasite promote its growth, 2021, Nature Communications
  • Nonlinear mechanics of human mitotic chromosomes, 2022, Nature
  • CENP-B-mediated DNA loops regulate activity and stability of human centromeres, 2022, Molecular Cell

Wuite's frequent coauthors include Erwin J.G. Peterman, Andreas S. Biebricher, Ian D. Hickson, Iddo Heller, and Hannes Witt.

Their work has been published extensively in venues such as Biophysical Journal, Methods in molecular biology, Nature Communications, bioRxiv (Cold Spring Harbor Laboratory), and Nucleic Acids Research.

Best Publications

  • Atomic force microscopy-based mechanobiology

    Michael Krieg;Gotthold Fläschner;David Alsteens;Benjamin M. Gaub

  • Single-molecule studies of the effect of template tension on T7 DNA polymerase activity

    Gijs J.L. Wuite;Steven B. Smith;Mark Young;David Keller

  • Grabbing the cat by the tail: manipulating molecules one by one.

    Carlos Bustamante;Jed C. Macosko;Gijs J. L. Wuite

  • Bacterial chromatin organization by H-NS protein unravelled using dual DNA manipulation.

    Remus T. Dame;Maarten C. Noom;Gijs J. L. Wuite

  • Single-molecule study of transcriptional pausing and arrest by E. coli RNA polymerase.

    R. John;Davenport;Gijs J. L. Wuite;Robert Landick

  • Bacteriophage capsids: tough nanoshells with complex elastic properties.

    I. L. Ivanovska;P. J. de Pablo;B. Ibarra;G. Sgalari

  • Nanoindentation studies of full and empty viral capsids and the effects of capsid protein mutations on elasticity and strength.

    J. P. Michel;I. L. Ivanovska;M. M. Gibbons;W. S. Klug

  • The architectural role of nucleoid-associated proteins in the organization of bacterial chromatin: a molecular perspective.

    Martijn S. Luijsterburg;Maarten C. Noom;Gijs J.L. Wuite;Remus Th. Dame

  • Unraveling the structure of DNA during overstretching by using multicolor, single-molecule fluorescence imaging

    Joost van Mameren;Peter Gross;Geraldine Farge;Pleuni Hooijman

  • Quantifying how DNA stretches, melts and changes twist under tension

    Peter Gross;Niels Laurens;Lene B. Oddershede;Ulrich Bockelmann

  • Acoustic force spectroscopy.

    Gerrit Sitters;Douwe Kamsma;Gregor Thalhammer;Monika Ritsch-Marte

  • STED nanoscopy combined with optical tweezers reveals protein dynamics on densely covered DNA

    Iddo Heller;Gerrit Sitters;Onno D Broekmans;Géraldine Farge

  • High-resolution mass spectrometry of viral assemblies: Molecular composition and stability of dimorphic hepatitis B virus capsids

    Charlotte Uetrecht;Cees Versluis;Norman R. Watts;Wouter H. Roos

  • Viral capsids: Mechanical characteristics, genome packaging and delivery mechanisms

    W. H. Roos;I. L. Ivanovska;Alex Evilevitch;G. J. L. Wuite

  • How DNA coiling enhances target localization by proteins

    B. van den Broek;M. A. Lomholt;S.-M. J. Kalisch;R. Metzler

  • Optical Tweezers Analysis of DNA–Protein Complexes

    Iddo Heller;Tjalle P Hoekstra;Graeme A King;Erwin J G Peterman

  • Facilitated diffusion with DNA coiling

    Michael A. Lomholt;Bram van den Broek;Svenja-Marei J. Kalisch;Gijs J. L. Wuite

  • Counting RAD51 proteins disassembling from nucleoprotein filaments under tension

    Joost van Mameren;Mauro Modesti;Mauro Modesti;Roland Kanaar;Claire Wyman

  • The impact of DNA intercalators on DNA and DNA-processing enzymes elucidated through force-dependent binding kinetics

    Andreas S Biebricher;Iddo Heller;Roel F H Roijmans;Tjalle P Hoekstra

  • Atomic force microscopy-based mechanobiology

    Michael Krieg;Gotthold Fläschner;David Alsteens;Benjamin M. Gaub

Frequent Co-Authors

Fred C. MacKintosh
Fred C. MacKintosh Rice University
Claire Wyman
Claire Wyman Erasmus MC
Raymond M. Schiffelers
Raymond M. Schiffelers Utrecht University
Ian D. Hickson
Ian D. Hickson University of Copenhagen
Carlos Bustamante
Carlos Bustamante Stanford University
Ralf Metzler
Ralf Metzler University of Potsdam
José L. Carrascosa
José L. Carrascosa Spanish National Research Council
Adam Zlotnick
Adam Zlotnick Indiana University
Maria Falkenberg
Maria Falkenberg University of Gothenburg

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