World's Best Scientists 2026 revealed!

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Immunology

D-Index
69
Citations
19069
World Ranking
2494
National Ranking
98

Overview

René Lutter is affiliated with the University of Amsterdam in the Netherlands and has published extensively in the field of medicine, with a particular focus on immunology, physiology, pulmonary and respiratory medicine, infectious diseases, and epidemiology.

Their research addresses diverse topics including asthma and respiratory diseases, IL-33, ST2, and ILC pathways, long-term effects of COVID-19, tryptophan and brain disorders, COVID-19 clinical research studies, neonatal respiratory health research, and SARS-CoV-2 and COVID-19 research.

René Lutter has contributed to numerous papers, some of the recent notable publications include:

  • "Viral presence and immunopathology in patients with lethal COVID-19: a prospective autopsy cohort study" (2020, The Lancet Microbe)
  • "Distinct cellular immune profiles in the airways and blood of critically ill patients with COVID-19" (2021, Thorax)
  • "Metabolic differences between bronchial epithelium from healthy individuals and patients with asthma and the effect of bronchial thermoplasty" (2021, Journal of Allergy and Clinical Immunology)
  • "Lung Microbiota of Critically Ill Patients with COVID-19 Are Associated with Nonresolving Acute Respiratory Distress Syndrome" (2022, American Journal of Respiratory and Critical Care Medicine)
  • "Concurrent Immune Suppression and Hyperinflammation in Patients With Community-Acquired Pneumonia" (2020, Frontiers in Immunology)

Frequent co-authors collaborating with René Lutter include:

  • Tamara Dekker (14 publications)
  • Tom van der Poll (13 publications)
  • Peter J. Sterk (12 publications)
  • JanWillem Duitman (10 publications)
  • Barbara Dierdorp (10 publications)

The scientist has published multiple articles in key venues such as:

  • ERJ Open Research (4 publications)
  • American Journal of Respiratory and Critical Care Medicine (3 publications)
  • Allergy (3 publications)
  • The Lancet Microbe (2 publications)
  • Journal of Allergy and Clinical Immunology (2 publications)

René Lutter's work primarily spans the intersecting domains of immunological responses and respiratory system pathophysiology, particularly in relation to infectious and chronic diseases affecting pulmonary function. Their research on the immune profiles of critically ill COVID-19 patients, as well as studies relating to asthma and bronchial conditions, contribute to understanding complex mechanisms underlying these health issues.

Best Publications

  • External validation of blood eosinophils, FE NO and serum periostin as surrogates for sputum eosinophils in asthma

    A H Wagener;S B de Nijs;R Lutter;A R Sousa

  • Viral presence and immunopathology in patients with lethal COVID-19: a prospective autopsy cohort study.

    Bernadette Schurink;Eva Roos;Teodora Radonic;Ellis Barbe

  • IL-1β, IL-4 and IL-12 control the fate of group 2 innate lymphoid cells in human airway inflammation in the lungs

    Suzanne M. Bal;Jochem H Bernink;Maho Nagasawa;Jelle Groot

  • IL-10 Is an Important Mediator of the Enhanced Susceptibility to Pneumococcal Pneumonia after Influenza Infection

    Koenraad F. van der Sluijs;Leontine J. R. van Elden;Monique Nijhuis;Rob Schuurman

  • Mechanical ventilation with lower tidal volumes and positive end-expiratory pressure prevents pulmonary inflammation in patients without preexisting lung injury.

    Esther K. Wolthuis;Goda Choi;Mark C. Dessing;Paul Bresser

  • T-helper cell type 2 (Th2) and non-Th2 molecular phenotypes of asthma using sputum transcriptomics in U-BIOPRED

    Chih-Hsi Scott Kuo;Chih-Hsi Scott Kuo;Stelios Pavlidis;Matthew Loza;Fred Baribaud

  • Acute respiratory distress syndrome leads to reduced ratio of ACE/ACE2 activities and is prevented by angiotensin-(1–7) or an angiotensin II receptor antagonist†

    Roelie M. Woesten-van Asperen;Rene Lutter;Patricia A. Specht;Gert N. Moll

  • Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency

    Sanja Kezic;Gráinne M. O’Regan;René Lutter;Ivone Jakasa

  • U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics

    Diane Lefaudeux;Bertrand De Meulder;Matthew J. Loza;Nancy Peffer

  • Neutrophil extracellular traps cause airway obstruction during respiratory syncytial virus disease.

    Bart Cortjens;Onno J. de Boer;Rineke de Jong;Adriaan F. G. Antonis

  • Interleukin-8 in airway inflammation in patients with asthma and chronic obstructive pulmonary disease.

    R. E. T. Nocker;D. F. M. Schoonbrood;E. A. Van De Graaf;C. E. Hack

  • Severe adult-onset asthma: A distinct phenotype.

    Marijke Amelink;Jantina C. de Groot;Selma B. de Nijs;Rene Lutter

  • Airway inflammation in nonobstructive and obstructive chronic bronchitis with chronic haemophilus influenzae airway infection. Comparison with noninfected patients with chronic obstructive pulmonary disease.

    P. Bresser;T. A. Out;L. van Alphen;H. M. Jansen

  • Absence of a classically activated macrophage cytokine signature in peripheral spondylarthritis, including psoriatic arthritis.

    Bernard Vandooren;Troy Noordenbos;Carmen Ambarus;Sarah Krausz

  • Three phenotypes of adult-onset asthma

    M. Amelink;S. B. de Nijs;J. C. de Groot;P. M. B. van Tilburg

  • Sputum transcriptomics reveal upregulation of IL-1 receptor family members in patients with severe asthma

    Christos Rossios;Stelios Pavlidis;Stelios Pavlidis;Uruj Hoda;Chih-Hsi Kuo

  • Exhaled air molecular profiling in relation to inflammatory subtype and activity in COPD

    N. Fens;S.B. De Nijs;S. Peters;T. Dekker

  • Toward clinically applicable biomarkers for asthma: An EAACI position paper.

    Zuzana Diamant;Zuzana Diamant;Susanne Vijverberg;Kjell Alving;Arzu Bakirtas

  • Antiinflammatory effects of salmeterol after inhalation of lipopolysaccharide by healthy volunteers.

    Nico A. Maris;Alex F. de Vos;Mark C. Dessing;C. Arnold Spek

  • Enhanced AP-1 and NF-kappaB activities and stability of interleukin 8 (IL-8) transcripts are implicated in IL-8 mRNA superinduction in lung epithelial H292 cells.

    Thierry Roger;A. Theo Out;Naofumi Mukaida;Kouji Matsushima

Frequent Co-Authors

Peter J. Sterk
Peter J. Sterk University of Amsterdam
Henk M. Jansen
Henk M. Jansen University of Amsterdam
Elisabeth H. Bel
Elisabeth H. Bel University of Amsterdam
Tom van der Poll
Tom van der Poll University of Amsterdam
Ian M. Adcock
Ian M. Adcock Imperial College London
Ratko Djukanovic
Ratko Djukanovic University of Southampton
Kian Fan Chung
Kian Fan Chung Imperial College London
Norbert Krug
Norbert Krug Fraunhofer Society
Charles Auffray
Charles Auffray Centre national de la recherche scientifique, CNRS
Peter H. Howarth
Peter H. Howarth University of Southampton

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