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Roderick A. Capaldi

Roderick A. Capaldi

D-Index & Metrics

Chemistry

D-Index
94
Citations
26481
World Ranking
1736
National Ranking
655

Biology and Biochemistry

D-Index
95
Citations
26832
World Ranking
1946
National Ranking
1065

Overview

Roderick A. Capaldi is affiliated with the University of Oregon in the United States. Their research primarily spans the fields of biochemistry, genetics, and molecular biology, with significant contributions in medicine. The subfields they work in include molecular biology, neurology, cellular and molecular neuroscience, and physiology.

The main topics of Roderick A. Capaldi's research focus on mitochondrial function and pathology, Parkinson's disease mechanisms and treatments, genetic neurodegenerative diseases, muscle physiology and disorders, and adipose tissue and metabolism.

Recent publications by Capaldi showcase work related to mitochondrial quality control in neurodegenerative diseases and muscle physiology. Notable papers include:

  • Parkinson's disease neurons exhibit alterations in mitochondrial quality control proteins, 2023, published in npj Parkinson s Disease
  • Decoding mitochondrial heterogeneity in single muscle fibres by imaging mass cytometry, 2020, published in Scientific Reports

These papers reflect engagement with both clinical and cellular aspects of mitochondrial biology in disease contexts. Capaldi's frequent co-authors include David McDonald, Andrew Filby, Amy E. Vincent, Chun Chen, and Alasdair Blain.

Their work has appeared primarily in the venues npj Parkinson s Disease and Scientific Reports. These outlets align with the interdisciplinary nature of Capaldi's research, bridging molecular mechanisms and clinical applications.

Best Publications

  • Investigating Mitochondrial Redox Potential with Redox-sensitive Green Fluorescent Protein Indicators

    George T. Hanson;Robert Aggeler;Devin Oglesbee;Mark Cannon

  • Energy Substrate Modulates Mitochondrial Structure and Oxidative Capacity in Cancer Cells

    Rodrigue Rossignol;Robert Gilkerson;Robert Aggeler;Kunihiro Yamagata

  • Parkinson's Disease Brain Mitochondrial Complex I Has Oxidatively Damaged Subunits and Is Functionally Impaired and Misassembled

    Paula M. Keeney;Jing Xie;Roderick A. Capaldi;James P. Bennett

  • Characterization of the human heart mitochondrial proteome.

    Steven W. Taylor;Eoin Fahy;Bing Zhang;Gary M. Glenn

  • STRUCTURE AND FUNCTION OF CYTOCHROME c OXIDASE

    Roderick A. Capaldi

  • Evidence for Boundary Lipid in Membranes

    Patricia C. Jost;O. Hayes Griffith;Roderick A. Capaldi;Garret Vanderkooi

  • The Low Polarity of Many Membrane Proteins

    Roderick A. Capaldi;Garret Vanderkooi

  • Mechanism of the F1F0-type ATP synthase, a biological rotary motor

    Roderick A Capaldi;Robert Aggeler

  • The cristal membrane of mitochondria is the principal site of oxidative phosphorylation.

    Robert W. Gilkerson;Jeanne M.L. Selker;Roderick A. Capaldi

  • Oxidative damage to mitochondrial complex I due to peroxynitrite: identification of reactive tyrosines by mass spectrometry.

    James Murray;Steven W. Taylor;Bing Zhang;Soumitra S. Ghosh

  • Characterization of a seventh different subunit of beef heart cytochrome c oxidase. Similarities between the beef heart enzyme and that from other species.

    Nancy W. Downer;Neal C. Robinson;Neal C. Robinson;Roderick A. Capaldi

  • 31P NMR study of improvement in oxidative phosphorylation by vitamins K3 and C in a patient with a defect in electron transport at complex III in skeletal muscle.

    S. Eleff;N. G. Kennaway;N. R. M. Buist;V. M. Darley-Usmar

  • Structure of cytochrome c oxidase.

    R.A. Capaldi;F. Malatesta;V.M. Darley-Usmar

  • Arrangement of proteins in the mitochondrial inner membrane

    Roderick A. Capaldi

  • The mitochondrial inner membrane protein Mitofilin exists as a complex with SAM50, metaxins 1 and 2, coiled-coil-helix coiled-coil-helix domain-containing protein 3 and 6 and DnaJC11

    Jing Xie;Michael F. Marusich;Puneet Souda;Julian Whitelegge

  • Analysis of steady-state protein phosphorylation in mitochondria using a novel fluorescent phosphosensor dye.

    Birte Schulenberg;Robert Aggeler;Joseph M. Beechem;Roderick A. Capaldi

  • Uniform nomenclature for the mitochondrial contact site and cristae organizing system

    Nikolaus Pfanner;Martin van der Laan;Paolo Amati;Roderick A. Capaldi

  • Diphosphatidylglycerol is required for optimal activity of beef heart cytochrome c oxidase

    Steven B. Vik;Gradimir Georgevich;Roderick A. Capaldi

  • Interaction of detergents with cytochrome c oxidase

    Neal C. Robinson;Roderick A. Capaldi

  • Arrangement of cytochrome oxidase molecules in two-dimensional vesicle crystals.

    R. Henderson;R.A. Capaldi;J.S. Leigh

Frequent Co-Authors

Victor M. Darley-Usmar
Victor M. Darley-Usmar University of Alabama at Birmingham
Bradford W. Gibson
Bradford W. Gibson Buck Institute for Research on Aging
Robert N. Lightowlers
Robert N. Lightowlers Newcastle University
Jan-Willem Taanman
Jan-Willem Taanman University College London
Frederick W. Dahlquist
Frederick W. Dahlquist University of California, Santa Barbara
Brian H. Robinson
Brian H. Robinson Hospital for Sick Children
Rosario Rizzuto
Rosario Rizzuto University of Padua
Birgit Schilling
Birgit Schilling Buck Institute for Research on Aging
Masasuke Yoshida
Masasuke Yoshida Kyoto Sangyo University
Jan A.M. Smeitink
Jan A.M. Smeitink Radboud University

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