World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
13199
World Ranking
13094
National Ranking
1025

Overview

Jan-Willem Taanman is affiliated with University College London in the United Kingdom. Their research spans 31 publications in the fields of Biochemistry, Genetics and Molecular Biology, and 26 in Medicine. The scientist has also contributed significantly to subfields including Molecular Biology, Clinical Biochemistry, Epidemiology, Pathology and Forensic Medicine, and Cancer Research.

The main topics covered in Taanman's work focus on mitochondrial function and pathology, metabolism and genetic disorders, ATP synthase and ATPases research, cancer, hypoxia, and metabolism, autophagy in disease and therapy, Parkinson's disease mechanisms and treatments, and lysosomal storage disorders research. These areas reflect a sustained interest in understanding cellular processes at a molecular level and their implications for human disease.

Frequent coauthors collaborating with Taanman include Jeries Abu-Hanna, Anthony H.V. Schapira, Micol Falabella, Luis Carlos Tabara, and Shanti Lu, each having coauthored multiple papers with them.

Notable recent papers include:

  • Mitochondria as target to inhibit proliferation and induce apoptosis of cancer cells: the effects of doxycycline and gemcitabine, 2020, Scientific Reports
  • Sirtuin 5 depletion impairs mitochondrial function in human proximal tubular epithelial cells, 2021, Scientific Reports
  • Exploring the impact of the PNPLA3 I148M variant on primary human hepatic stellate cells using 3D extracellular matrix models, 2024, Journal of Hepatology
  • Huntington's disease affects mitochondrial network dynamics predisposing to pathogenic mitochondrial DNA mutations, 2024, Brain
  • Ambroxol reverses tau and α-synuclein accumulation in a cholinergic N370S GBA1 mutation model, 2022, Human Molecular Genetics

Taanman's research has been published frequently in venues such as the Journal of Hepatology, PLoS ONE, Scientific Reports, Brain, and Biochimica et Biophysica Acta (BBA) - Bioenergetics, with multiple contributions to each.

Best Publications

  • The mitochondrial genome: structure, transcription, translation and replication

    Jan Willem Taanman

  • Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy

    Matthew E. Gegg;J. Mark Cooper;Kai-Yin Chau;Manuel Rojo

  • Biochemical abnormalities and excitotoxicity in Huntington's disease brain

    S. J. Tabrizi;M. W. J. Cleeter;J. Xuereb;J.-W. Taanman

  • Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus

    Michael J. Devine;Mina Ryten;Petr Vodicka;Alison J. Thomson

  • Mitochondrial DNA transmission of the mitochondrial defect in Parkinson's disease.

    M. Gu;J. M. Cooper;J. W. Taanman;A. H. V. Schapira

  • A mutant mitochondrial respiratory chain assembly protein causes complex III deficiency in patients with tubulopathy, encephalopathy and liver failure

    Pascale De Lonlay;Isabelle Valnot;Antoni Barrientos;Marina Gorbatyuk

  • A mutation in the human heme A:farnesyltransferase gene (COX10 ) causes cytochrome c oxidase deficiency

    Isabelle Valnot;Jürgen Christoph Von Kleist-Retzow;Antonio Barrientos;Marina Gorbatyuk

  • Cytochrome c Oxidase subunit I microdeletion in a patient with motor neuron disease

    Giacomo P. Comi;Andreina Bordoni;Sabrina Salani;Liliana Franceschina

  • Assembly of cytochrome‐c oxidase in cultured human cells

    Leo G. J. Nijtmans;Jan-Willem Taanman;Anton O. Muijsers;Dave Speijer

  • Mitochondria in the etiology and pathogenesis of Parkinson's disease

    A. H. V. Schapira;M. Gu;J.-W. Taanman;S. J. Tabrizi

  • Silencing of PINK1 expression affects mitochondrial DNA and oxidative phosphorylation in dopaminergic cells.

    Matthew E. Gegg;J. Mark Cooper;Anthony H. V. Schapira;Jan-Willem Taanman

  • Expression of mutant α-synuclein causes increased susceptibility to dopamine toxicity

    Sarah J. Tabrizi;Michael Orth;J. Max Wilkinson;Jan-Willem Taanman

  • Mammalian cytochrome-c oxidase: characterization of enzyme and immunological detection of subunits in tissue extracts and whole cells.

    Roderick A. Capaldi;Michael F. Marusich;Jan-Willem Taanman

  • Cytochrome c Oxidase Subassemblies in Fibroblast Cultures from Patients Carrying Mutations in COX10, SCO1, or SURF1

    Siôn L. Williams;Isabelle Valnot;Pierre Rustin;Jan Willem Taanman

  • Dominant inheritance of premature ovarian failure associated with mutant mitochondrial DNA polymerase gamma

    Alistair T Pagnamenta;Jan-Willem Taanman;Callum J Wilson;Neil E Anderson

  • Molecular Mechanisms in Mitochondrial DNA Depletion Syndrome

    J.-W. Taanman;A. G. Bodnar;J. M. Cooper;A. A. M. Morris

  • Status epilepticus in children with Alpers' disease caused by POLG1 mutations: EEG and MRI features.

    Nicole I. Wolf;Shamima Rahman;Bernhard Schmitt;Jan-Willem Taanman

  • Expression of mtDNA and nDNA encoded respiratory chain proteins in chemically and genetically-derived Rho0 human fibroblasts: a comparison of subunit proteins in normal fibroblasts treated with ethidium bromide and fibroblasts from a patient with mtDNA depletion syndrome.

    Michael F Marusich;Brian H Robinson;Jan-Willem Taanman;Soo Jin Kim

  • A missense mutation of cytochrome oxidase subunit II causes defective assembly and myopathy.

    Shamima Rahman;Jan-Willem Taanman;J. Mark Cooper;Isabelle Nelson

  • NDUFA4 mutations underlie dysfunction of a cytochrome c oxidase subunit linked to human neurological disease.

    Robert D.S. Pitceathly;Shamima Rahman;Shamima Rahman;Yehani Wedatilake;James M. Polke

Frequent Co-Authors

Anthony H.V. Schapira
Anthony H.V. Schapira University College London
Shamima Rahman
Shamima Rahman University College London
Michael G. Hanna
Michael G. Hanna University College London
Michael Orth
Michael Orth University of Ulm
Peter E. Clayton
Peter E. Clayton University of Manchester
Janice L. Holton
Janice L. Holton University College London
Roderick A. Capaldi
Roderick A. Capaldi University of Oregon
Iain P. Hargreaves
Iain P. Hargreaves Liverpool John Moores University
Henry Houlden
Henry Houlden University College London
Massimo Zeviani
Massimo Zeviani University of Padua

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

The fields of Biology and Biochemistry offer diverse career paths, many of which can begin with online education. Aspiring healthcare professionals may consider enrolling in an online ASN program to fast-track their entry into nursing careers, an in-demand field linked to biology fundamentals.

Those interested in nutrition science and how biological processes impact human health might pursue the best online nutrition degree. This path prepares graduates for roles in health education, wellness consulting, and research.

For students drawn to healthcare administration, it’s important to choose an advanced degree from among the growing number of CAHME-accredited MHA programs. CAHME accreditation ensures program quality and can enhance career prospects in leadership roles.

Finally, those looking to achieve the highest nursing credentials may benefit from an online Doctor of Nursing Practice program—some of which emphasize research and leadership and do not require clinical placements.

Exploring these related online degrees offers flexible, accessible pathways into rewarding scientific and healthcare professions.

Best Scientists Citing Jan-Willem Taanman

Trending Scientists

Recently Published Articles