World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
66
Citations
14934
World Ranking
2621
National Ranking
11

Overview

Laurence A. Bindoff is affiliated with Haukeland University Hospital in Norway. The scientist's primary research focus lies in the fields of Biochemistry, Genetics, and Molecular Biology, with a total of 118 publications. Within these fields, Bindoff has contributed significantly to subfields including Molecular Biology, Genetics, Clinical Biochemistry, Cellular and Molecular Neuroscience, and Physiology.

Bindoff's research covers several main topics, notably Mitochondrial Function and Pathology, Metabolism and Genetic Disorders, ATP Synthase and ATPases Research, Pluripotent Stem Cells Research, Genetics and Neurodevelopmental Disorders, RNA Research and Splicing, and Genetic Neurodegenerative Diseases.

Notable recent papers authored by Bindoff include:

  • Mitochondrial disease in adults: recent advances and future promise, 2021, The Lancet Neurology
  • Simplifying the clinical classification of polymerase gamma (POLG) disease based on age of onset; studies using a cohort of 155 cases, 2020, Journal of Inherited Metabolic Disease
  • Safety of drug use in patients with a primary mitochondrial disease: An international Delphi-based consensus, 2020, Journal of Inherited Metabolic Disease
  • Disease-specific phenotypes in iPSC-derived neural stem cells with POLG mutations, 2020, EMBO Molecular Medicine
  • Diagnostic value of serum biomarkers FGF21 and GDF15 compared to muscle sample in mitochondrial disease, 2020, Journal of Inherited Metabolic Disease

Frequent co-authors collaborating with Bindoff include:

  • Kristina Xiao Liang
  • Gareth J. Sullivan
  • Anbin Chen
  • Cecilie Katrin Kristiansen
  • Omar Hikmat

Bindoff's work has been published repeatedly in several venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Annals of Clinical and Translational Neurology
  • Journal of Inherited Metabolic Disease
  • Journal of Visualized Experiments
  • Experimental Neurology

Best Publications

  • Mutation in the gene encoding ferritin light polypeptide causes dominant adult-onset basal ganglia disease.

    Andrew R.J. Curtis;Constanze Fey;Christopher M Morris;Laurence A. Bindoff

  • Correlation between genetic and geographic structure in Europe.

    Oscar Lao;Timothy T. Lu;Michael Nothnagel;Olaf Junge

  • The epidemiology of pathogenic mitochondrial DNA mutations.

    P. F. Chinnery;M. A. Johnson;T. M. Wardell;R. Singh-Kler

  • Leber Hereditary Optic Neuropathy: Identification of the Same Mitochondrial ND1 Mutation in Six Pedigrees

    N Howell;L A Bindoff;D A McCullough;I Kubacka

  • Multi-system neurological disease is common in patients with OPA1 mutations

    Patrick Yu-Wai-Man;Philip G. Griffiths;Philip G. Griffiths;G. Gorman;C.-M. Lourenco

  • FGF-21 as a biomarker for muscle-manifesting mitochondrial respiratory chain deficiencies: a diagnostic study.

    Anu Suomalainen;Anu Suomalainen;Jenni M Elo;Kirsi H Pietiläinen;Anna H Hakonen

  • The spectrum of clinical disease caused by the A467T and W748S POLG mutations: a study of 26 cases

    Charalampos Tzoulis;Bernt A. Engelsen;Wenche Telstad;Jan Aasly

  • Mitochondrial DNA polymerase W748S mutation: a common cause of autosomal recessive ataxia with ancient European origin

    Anna H. Hakonen;Silja Heiskanen;Vesa Juvonen;Ilse Lappalainen

  • An Evaluation of the Measurement of the Activities of Complexes I-IV in the Respiratory Chain of Human Skeletal Muscle Mitochondria

    M.A. Birchmachin;H.L. Briggs;A.A. Saborido;L.A. Bindoff

  • MITOCHONDRIAL FUNCTION IN PARKINSON'S DISEASE

    L.A. Bindoff;M. Birch-Machin;N.E.F. Cartlidge;W.D. Parker

  • Autosomal recessive mitochondrial ataxic syndrome due to mitochondrial polymerase γ mutations

    S. Winterthun;G. Ferrari;L. He;R. W. Taylor

  • Risk of developing a mitochondrial DNA deletion disorder

    Patrick F Chinnery;Salvatore DiMauro;Sara Shanske;Eric A Schon

  • Respiratory chain abnormalities in skeletal muscle from patients with Parkinson's disease

    L.A. Bindoff;M.A. Birch-Machin;N.E.F. Cartlidge;W.D. Parker

  • Mutations in ABHD12 Cause the Neurodegenerative Disease PHARC: An Inborn Error of Endocannabinoid Metabolism

    Torunn Fiskerstrand;Dorra H'mida-Ben Brahim;Stefan Johansson;Abderrahim M'zahem

  • A new mtDNA mutation showing accumulation with time and restriction to skeletal muscle.

    K Weber;J N Wilson;L Taylor;E Brierley

  • Defective mitochondrial DNA homeostasis in the substantia nigra in Parkinson disease

    Christian Dölle;Irene Hana Flønes;Irene Hana Flønes;Gonzalo Sanchez Nido;Gonzalo Sanchez Nido;Hrvoje Miletic

  • A multicenter study on Leigh syndrome: Disease course and predictors of survival

    Kalliopi Sofou;Irenaeus F M De Coo;Pirjo Isohanni;Pirjo Isohanni;Elsebet Ostergaard

  • Abnormal RNA processing associated with a novel tRNA mutation in mitochondrial DNA. A potential disease mechanism.

    L A Bindoff;N Howell;J Poulton;D A McCullough

  • Germline mutations in WTX cause a sclerosing skeletal dysplasia but do not predispose to tumorigenesis

    Zandra A Jenkins;Margriet van Kogelenberg;Tim Morgan;Aaron Jeffs

  • New treatments for mitochondrial disease—no time to drop our standards

    Gerald Pfeffer;Rita Horvath;Thomas Klopstock;Vamsi K. Mootha

Frequent Co-Authors

Douglass M. Turnbull
Douglass M. Turnbull Newcastle University
Robert W. Taylor
Robert W. Taylor Newcastle University
Stefan Johansson
Stefan Johansson University of Bergen
Patrick F. Chinnery
Patrick F. Chinnery University of Cambridge
Massimo Zeviani
Massimo Zeviani University of Padua
Christian A. Vedeler
Christian A. Vedeler University of Bergen
Robert McFarland
Robert McFarland Newcastle University
Mark A. Birch-Machin
Mark A. Birch-Machin Newcastle University
Rita Horvath
Rita Horvath University of Cambridge
Robert N. Lightowlers
Robert N. Lightowlers Newcastle University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Genetics in the USA opens the door to many online education options and career paths in healthcare and science. If you’re interested in combining genetics with healthcare administration, consider looking into online medical coding programs which can provide knowledge in medical data and terminology, skills often valued in clinical genetics settings.

For those eager to enter the workforce quickly, a fast track bachelor degree is an efficient way to gain essential qualifications in less time. Such programs can accelerate your path to careers in biotechnology, bioinformatics, or laboratory management.

Flexibility is key for many students. With online self paced colleges, you can complete genetics-related coursework at your own speed, making it easier to balance studies with work or family commitments.

Prospective students can also streamline their admission process by searching for programs like majuba college online application, which highlights colleges that waive application fees—removing financial barriers to pursuing a genetics-focused education online.

Best Scientists Citing Laurence A. Bindoff

Trending Scientists