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Mark A. Birch-Machin

Mark A. Birch-Machin

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
12614
World Ranking
13762
National Ranking
1075

Overview

Mark A. Birch-Machin is affiliated with Newcastle University in the United Kingdom. Their research primarily focuses on the field of medicine, with a particular emphasis on dermatology, health, toxicology and mutagenesis, molecular biology, epidemiology, and physiology.

The main topics explored in Birch-Machin's work include:

  • Skin Protection and Aging
  • Adipose Tissue and Metabolism
  • Circadian rhythm and melatonin
  • Air Quality and Health Impacts
  • Indoor Air Quality and Microbial Exposure
  • Antioxidant Activity and Oxidative Stress
  • Adipokines, Inflammation, and Metabolic Diseases

A selection of recent papers authored or co-authored by Birch-Machin includes:

  • "Microneedle-based devices for point-of-care infectious disease diagnostics," 2021, Acta Pharmaceutica Sinica B
  • "Individual and combined effects of the infrared, visible, and ultraviolet light components of solar radiation on damage biomarkers in human skin cells," 2020, The FASEB Journal
  • "Exploration of Sleep as a Specific Risk Factor for Poor Metabolic and Mental Health: A UK Biobank Study of 84,404 Participants," 2021, Nature and Science of Sleep
  • "Metabolic dysfunction in human skin: Restoration of mitochondrial integrity and metabolic output by nicotinamide (niacinamide) in primary dermal fibroblasts from older aged donors," 2020, Aging Cell
  • "Targeting mitochondria in dermatological therapy: beyond oxidative damage and skin aging," 2022, Expert Opinion on Therapeutic Targets

Birch-Machin's frequent co-authors include:

  • Bhaven Chavan
  • Gewei Zhu
  • Amy Bowman
  • Wil J. Reynolds
  • Jessica Moor

The researcher has published extensively in various venues, with multiple publications in:

  • The FASEB Journal
  • FASEB BioAdvances
  • British Journal of Dermatology
  • Acta Pharmaceutica Sinica B
  • Nature and Science of Sleep

Best Publications

  • Mutation of a nuclear succinate dehydrogenase gene results in mitochondrial respiratory chain deficiency

    Thomas Bourgeron;Pierre Rustin;Dominique Chretien;Mark Birch-Machin

  • Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence.

    João F Passos;Gabriele Saretzki;Gabriele Saretzki;Shaheda Ahmed;Shaheda Ahmed;Glyn Nelson

  • Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress.

    Shaheda Ahmed;João F. Passos;Matthew J. Birket;Tina Beckmann

  • Evidence for Variable Selective Pressures at MC1R

    Rosalind M. Harding;Eugene Healy;Amanda J. Ray;Nichola S. Ellis

  • Assaying mitochondrial respiratory complex activity in mitochondria isolated from human cells and tissues.

    Mark A. Birch-Machin;Douglass M. Turnbull

  • Mitochondria-targeted antioxidants

    Anne O. Oyewole;Mark A. Birch-Machin

  • Clinical implications and utility of field cancerization

    Gabriel D Dakubo;John P Jakupciak;Mark A Birch-Machin;Ryan L Parr

  • Pleiotropic effects of the melanocortin 1 receptor (MC1R) gene on human pigmentation

    Niamh Flanagan;Eugene Healy;Amanda Ray;Sion Philips

  • An Evaluation of the Measurement of the Activities of Complexes I-IV in the Respiratory Chain of Human Skeletal Muscle Mitochondria

    M.A. Birchmachin;H.L. Briggs;A.A. Saborido;L.A. Bindoff

  • Melanocortin 1 receptor variants in an Irish population

    Rachel Smith;Eugene Healy;Shazia Siddiqui;Niamh Flanagan

  • MITOCHONDRIAL FUNCTION IN PARKINSON'S DISEASE

    L.A. Bindoff;M. Birch-Machin;N.E.F. Cartlidge;W.D. Parker

  • Loss of function mutations of the human melanocortin 1 receptor are common and are associated with red hair.

    Helgi B. Schiöth;Siôn R. Phillips;Richard Rudzish;Mark A. Birch-Machin

  • Towards a “free radical theory of graying”: melanocyte apoptosis in the aging human hair follicle is an indicator of oxidative stress induced tissue damage

    Petra Clara Arck;Rupert Overall;Katharina Spatz;Christiane Liezman

  • Respiratory chain abnormalities in skeletal muscle from patients with Parkinson's disease

    L.A. Bindoff;M.A. Birch-Machin;N.E.F. Cartlidge;W.D. Parker

  • Increasing melanoma cell death using inhibitors of protein disulfide isomerases to abrogate survival responses to endoplasmic reticulum stress

    Penny E. Lovat;Marco Corazzari;Jane L. Armstrong;Shaun Martin

  • Oxidative stress and ageing

    Mark Birch-Machin;Amy Bowman

  • Tomato paste rich in lycopene protects against cutaneous photodamage in humans in vivo: A randomized controlled trial

    M. Rizwan;I. Rodriguez-Blanco;A. Harbottle;M.A. Birch-Machin

  • Late-onset optic atrophy, ataxia, and myopathy associated with a mutation of a complex II gene.

    Mark A. Birch-Machin;Robert W. Taylor;Bruce Cochran;Brian A. C. Ackrell

  • Melanocortin-1-receptor gene and sun sensitivity in individuals without red hair

    Eugene Healy;Eugene Healy;Niamh Flannagan;Amanda Ray;Carole Todd

  • Mitochondrial DNA deletions in human skin reflect photo-rather than chronologic aging

    Mark A. Birch-machin;May Tindall;Richard Turner;Faye Haldane

Frequent Co-Authors

Douglass M. Turnbull
Douglass M. Turnbull Newcastle University
Eugene Healy
Eugene Healy University of Southampton
Jonathan L. Rees
Jonathan L. Rees University of Edinburgh
Laurence A. Bindoff
Laurence A. Bindoff Haukeland University Hospital
Ian J. Jackson
Ian J. Jackson University of Edinburgh
Robert W. Taylor
Robert W. Taylor Newcastle University
Falko F. Sniehotta
Falko F. Sniehotta Newcastle University
Gabriele Saretzki
Gabriele Saretzki Newcastle University
João F. Passos
João F. Passos Mayo Clinic
Mauro Piacentini
Mauro Piacentini University of Rome Tor Vergata

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