What is he best known for?
The fields of study he is best known for:
Genetics, Genome-wide association study, Allele, Single-nucleotide polymorphism and Genetic association are his primary areas of study.
His work on Genetics deals in particular with Locus, Epigenetics, Quantitative trait locus, Methylation and Regulation of gene expression.
His research integrates issues of Common disease-common variant, Bone mineral, Bone density, Osteoporosis and Genetic architecture in his study of Genome-wide association study.
His Allele study integrates concerns from other disciplines, such as Nevus, CDKN2A and Cutaneous melanoma.
The Single-nucleotide polymorphism study combines topics in areas such as Melanoma, Computational biology and Skin cancer.
His research investigates the connection between Genetic association and topics such as Candidate gene that intersect with problems in CAD, Coronary artery disease and Bioinformatics.
His most cited work include:
- Hundreds of variants clustered in genomic loci and biological pathways affect human height (1614 citations)
- Large-scale association analysis identifies new risk loci for coronary artery disease (1172 citations)
- Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture (845 citations)
What are the main themes of his work throughout his whole career to date?
Tomi Pastinen focuses on Genetics, Gene, Single-nucleotide polymorphism, Allele and DNA methylation.
His Genetics and Genome-wide association study, Genetic variation, Locus, Haplotype and Genetic association investigations all form part of his Genetics research activities.
His Genome-wide association study study which covers Bone mineral that intersects with Bone density.
Tomi Pastinen works mostly in the field of Single-nucleotide polymorphism, limiting it down to concerns involving Immunology and, occasionally, Disease.
His research ties Genotype and Allele together.
His work deals with themes such as Chromatin, Methylation and Epigenetics, which intersect with DNA methylation.
He most often published in these fields:
- Genetics (67.16%)
- Gene (31.34%)
- Single-nucleotide polymorphism (24.38%)
What were the highlights of his more recent work (between 2018-2021)?
- DNA methylation (26.37%)
- Genetics (67.16%)
- Disease (10.45%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are DNA methylation, Genetics, Disease, Gene and Methylation.
His DNA methylation study combines topics in areas such as Histone and Epigenetics.
His Genetics research incorporates themes from Allergy and Cohort.
His Methylation research integrates issues from Genome-wide association study and Genotype.
His research in Genome-wide association study intersects with topics in Candidate gene and Endothelial dysfunction.
Allelic Imbalance is closely connected to Single-nucleotide polymorphism in his research, which is encompassed under the umbrella topic of Locus.
Between 2018 and 2021, his most popular works were:
- H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis. (70 citations)
- H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis. (70 citations)
- Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes (51 citations)
In his most recent research, the most cited papers focused on:
His scientific interests lie mostly in Disease, Computational biology, Epigenome, DNA methylation and Genome-wide association study.
His biological study spans a wide range of topics, including Gene, Locus and Indel.
His work is dedicated to discovering how Locus, Candidate gene are connected with Chromatin and Single-nucleotide polymorphism and other disciplines.
Tomi Pastinen interconnects Bioethics and Personal Genome Project in the investigation of issues within Epigenome.
Tomi Pastinen has included themes like Carcinogenesis, Regulation of gene expression, Histone and Neurogenesis in his DNA methylation study.
His Genome-wide association study research is multidisciplinary, relying on both DNA microarray, Methylation, Epigenetics and Gene expression profiling.
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