World's Best Scientists 2026 revealed!
Mohamed N. Seleem

Mohamed N. Seleem

D-Index & Metrics

Microbiology

D-Index
53
Citations
10100
World Ranking
4094
National Ranking
1586

Overview

Mohamed N. Seleem is affiliated with Virginia Tech in the United States and has an extensive publication record across several fields related to medicine and molecular biology. Their research spans a variety of topics within infectious diseases, microbiology, and organic chemistry.

The scientist has contributed substantially to the understanding of antimicrobial resistance, enzyme function, and inhibition, focusing on bacterial and fungal pathogens. Key research topics include:

  • Antifungal resistance and susceptibility
  • Phenothiazines and Benzothiazines synthesis and activities
  • Clostridium difficile and Clostridium perfringens research
  • Enzyme function and inhibition
  • Antimicrobial resistance in Staphylococcus
  • Fungal infections and studies
  • Synthesis and biological evaluation

Mohamed N. Seleem's research appears predominantly in the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant work in infectious diseases, molecular biology, organic chemistry, epidemiology, and microbiology. This portfolio indicates a broad interdisciplinary approach to tackling infectious disease challenges.

The frequent coauthors collaborating with Seleem include:

  • Nader S. Abutaleb
  • Ehab A. Salama
  • Daniel P. Flaherty
  • Abdelrahman S. Mayhoub
  • Yehia Elgammal

The scientist's work is published in a range of journals and publication venues, highlighting a diverse but focused dissemination strategy. Frequent venues include:

  • Scientific Reports
  • PLoS ONE
  • Antimicrobial Agents and Chemotherapy
  • Journal of Medicinal Chemistry
  • European Journal of Medicinal Chemistry

Selected recent papers reflect the thematic and methodological breadth of their research:

  • The value of antimicrobial peptides in the age of resistance (2020), published in The Lancet Infectious Diseases
  • Rapid Determination of Antimicrobial Susceptibility by Stimulated Raman Scattering Imaging of D2O Metabolic Incorporation in a Single Bacterium (2020), published in Advanced Science
  • Genetic basis of molecular mechanisms in β-lactam resistant gram-negative bacteria (2021), published in Microbial Pathogenesis
  • Optimization of Acetazolamide-Based Scaffold as Potent Inhibitors of Vancomycin-Resistant Enterococcus (2020), published in Journal of Medicinal Chemistry
  • Structure-Activity Relationship Studies of Acetazolamide-Based Carbonic Anhydrase Inhibitors with Activity against Neisseria gonorrhoeae (2021), published in ACS Infectious Diseases

Best Publications

  • Brucellosis: A re-emerging zoonosis

    Mohamed N. Seleem;Stephen M. Boyle;Nammalwar Sriranganathan

  • The value of antimicrobial peptides in the age of resistance

    Maria Magana;Muthuirulan Pushpanathan;Ana L Santos;Leon Leanse

  • Evaluation of short synthetic antimicrobial peptides for treatment of drug-resistant and intracellular Staphylococcus aureus

    Mohamed F. Mohamed;Ahmed Abdelkhalek;Mohamed N. Seleem

  • Antibacterial activity and mechanism of action of auranofin against multi-drug resistant bacterial pathogens.

    Shankar Thangamani;Haroon Mohammad;Mostafa F. N. Abushahba;Mostafa F. N. Abushahba;Tiago J. P. Sobreira

  • Brucella: a pathogen without classic virulence genes.

    Mohamed N. Seleem;Stephen M. Boyle;Nammalwar Sriranganathan

  • Dual Targeting of Intracellular Pathogenic Bacteria with a Cleavable Conjugate of Kanamycin and an Antibacterial Cell-Penetrating Peptide

    Anna Brezden;Mohamed F. Mohamed;Manish Nepal;John S. Harwood

  • Repurposing ebselen for treatment of multidrug-resistant staphylococcal infections

    Shankar Thangamani;Waleed Younis;Mohamed N. Seleem

  • Exploring simvastatin, an antihyperlipidemic drug, as a potential topical antibacterial agent.

    Shankar Thangamani;Haroon Mohammad;Mostafa F. N. Abushahba;Mostafa F. N. Abushahba;Maha I. Hamed;Maha I. Hamed

  • Phenotypic Profiling of Antibiotic Response Signatures in Escherichia coli Using Raman Spectroscopy

    A. I. M. Athamneh;R. A. Alajlouni;R. S. Wallace;M. N. Seleem

  • Discovery and Characterization of Potent Thiazoles versus Methicillin- and Vancomycin-Resistant Staphylococcus aureus

    Haroon Mohammad;Abdelrahman S. Mayhoub;Adil Ghafoor;Muhammad Soofi

  • Rapid Determination of Antimicrobial Susceptibility by Stimulated Raman Scattering Imaging of D2O Metabolic Incorporation in a Single Bacterium

    Meng Zhang;Weili Hong;Nader S. Abutaleb;Junjie Li

  • Targeting Brucella melitensis with polymeric nanoparticles containing streptomycin and doxycycline.

    Mohamed N. Seleem;Mohamed N. Seleem;Neeta Jain;Nikorn Pothayee;Ashish Ranjan

  • Targeting Methicillin-Resistant Staphylococcus aureus with Short Salt-Resistant Synthetic Peptides

    Mohamed F. Mohamed;Maha I. Hamed;Alyssa Panitch;Mohamed N. Seleem

  • Ebselen exerts antifungal activity by regulating glutathione (GSH) and reactive oxygen species (ROS) production in fungal cells.

    Shankar Thangamani;Hassan E. Eldesouky;Haroon Mohammad;Pete E. Pascuzzi

  • A short D-enantiomeric antimicrobial peptide with potent immunomodulatory and antibiofilm activity against multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii

    Mohamed F. Mohamed;Anna Brezden;Haroon Mohammad;Jean Chmielewski

  • Silica-Antibiotic Hybrid Nanoparticles for Targeting Intracellular Pathogens

    Mohamed N. Seleem;Prabhakaran Munusamy;Ashish Ranjan;Hamzeh Alqublan

  • Synthesis and antibacterial evaluation of a novel series of synthetic phenylthiazole compounds against methicillin-resistant Staphylococcus aureus (MRSA).

    Haroon Mohammad;P.V. Narasimha Reddy;Dennis Monteleone;Abdelrahman S. Mayhoub

  • Repurposing Non-Antimicrobial Drugs and Clinical Molecules to Treat Bacterial Infections.

    Waleed Younis;Shankar Thangamani;Mohamed N. Seleem

  • Antibiotic Susceptibility Determination within One Cell Cycle at Single-Bacterium Level by Stimulated Raman Metabolic Imaging

    Weili Hong;Caroline W. Karanja;Nader S. Abutaleb;Waleed Younis

  • Anti-biofilm activity and synergism of novel thiazole compounds with glycopeptide antibiotics against multidrug-resistant Staphylococci

    Haroon Mohammad;Abdelrahman S Mayhoub;Mark Cushman;Mohamed N Seleem

  • Repurposing celecoxib as a topical antimicrobial agent.

    Shankar Thangamani;Waleed Younis;Mohamed N. Seleem

Frequent Co-Authors

Ji-Xin Cheng
Ji-Xin Cheng Boston University
George Y. Liu
George Y. Liu University of California, San Diego
Mark Cushman
Mark Cushman Purdue University West Lafayette
Herman O. Sintim
Herman O. Sintim Purdue University West Lafayette
Judy S. Riffle
Judy S. Riffle Virginia Tech
Qiang Cui
Qiang Cui Boston University
Eric Oldfield
Eric Oldfield University of Illinois at Urbana-Champaign
Kit Pogliano
Kit Pogliano University of California, San Diego
Yoon Yeo
Yoon Yeo Purdue University West Lafayette

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