World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
46
Citations
8275
World Ranking
15989
National Ranking
3993

Overview

Herman O. Sintim is affiliated with Purdue University West Lafayette in the United States. Their research primarily spans the fields of Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. Subfields of particular interest include Molecular Biology, Immunology, Infectious Diseases, Organic Chemistry, and Pulmonary and Respiratory Medicine.

The scientist's recent publications demonstrate a focus on antimicrobial agents, bacterial growth inhibition, and cancer therapy. Notable recent papers include:

  • Lipoteichoic Acid Biosynthesis Inhibitors as Potent Inhibitors of S. aureus and E. faecalis Growth and Biofilm Formation, 2020, published in Molecules
  • Multiple Ways to Kill Bacteria Via Inhibiting Novel Cell Wall Or Membrane Targets, 2020, published in Future Medicinal Chemistry
  • RET aberrant cancers and RET inhibitor therapies: Current state-of-the-art and future perspectives, 2023, published in Pharmacology & Therapeutics
  • Ultrapotent Inhibitor of Clostridioides difficile Growth, Which Suppresses Recurrence In Vivo, 2020, published in Journal of Medicinal Chemistry
  • Use of High-Throughput Tools for Telescoped Continuous Flow Synthesis of an Alkynylnaphthyridine Anticancer Agent, HSN608, 2020, published in Organic Process Research & Development

The scientist's work contributes to several research topics, including:

  • Interferon and immune responses
  • Viral infections and vectors
  • Immune response and inflammation
  • Antibiotic resistance in bacteria
  • Lung cancer treatments and mutations
  • Antimicrobial resistance in Staphylococcus
  • Bacterial biofilms and quorum sensing

Their frequent co-authors are Neetu Dayal, Kenneth I. Onyedibe, Uma K. Aryal, George A. Naclerio, and Nickolas R. Brauer.

Herman O. Sintim's publications are often featured in journals such as RSC Medicinal Chemistry, Journal of Medicinal Chemistry, ACS Infectious Diseases, European Journal of Medicinal Chemistry, and Molecules.

Best Publications

  • Biofilm formation mechanisms and targets for developing antibiofilm agents

    Nira Rabin;Yue Zheng;Clement Opoku-Temeng;Yixuan Du

  • Isothermal amplified detection of DNA and RNA

    Lei Yan;Jie Zhou;Yue Zheng;Adam S. Gamson

  • Nucleotide, c-di-GMP, c-di-AMP, cGMP, cAMP, (p)ppGpp signaling in bacteria and implications in pathogenesis

    Dimpy Kalia;Gökçe Merey;Gökçe Merey;Shizuka Nakayama;Yue Zheng

  • Agents that inhibit bacterial biofilm formation

    Nira Rabin;Yue Zheng;Clement Opoku-Temeng;Yixuan Du

  • STING Ligand c-di-GMP Improves Cancer Vaccination against Metastatic Breast Cancer

    Dinesh Chandra;Wilber Quispe-Tintaya;Arthee Jahangir;Denise Asafu-Adjei

  • Differential radial capillary action of ligand assay for high-throughput detection of protein-metabolite interactions

    Kevin G. Roelofs;Jingxin Wang;Herman O. Sintim;Vincent T. Lee

  • Molecular Fluorescence, Phosphorescence, and Chemiluminescence Spectrometry

    Susmita Das;Aleeta M. Powe;Gary A. Baker;Bertha Valle

  • Colorimetric split G-quadruplex probes for nucleic acid sensing: improving reconstituted DNAzyme's catalytic efficiency via probe remodeling.

    Shizuka Nakayama;Herman O Sintim

  • Paradigm shift in discovering next-generation anti-infective agents: targeting quorum sensing, c-di-GMP signaling and biofilm formation in bacteria with small molecules.

    Herman O Sintim;Jacqueline A I Smith;Jingxin Wang;Shizuka Nakayama

  • Unraveling curcumin degradation: autoxidation proceeds through spiroepoxide and vinylether intermediates en route to the main bicyclopentadione.

    Odaine N. Gordon;Paula B. Luis;Herman O. Sintim;Claus Schneider

  • Oligoribonuclease is the primary degradative enzyme for pGpG in Pseudomonas aeruginosa that is required for cyclic-di-GMP turnover

    Mona W. Orr;Gregory P. Donaldson;Geoffrey B. Severin;Jingxin Wang

  • Suramin potently inhibits cGAMP synthase, cGAS, in THP1 cells to modulate IFN-β levels.

    Modi Wang;Moloud A Sooreshjani;Clinton Mikek;Clement Opoku-Temeng;Clement Opoku-Temeng

  • AI-2 analogs and antibiotics: a synergistic approach to reduce bacterial biofilms

    Varnika Roy;Mariana T. Meyer;Jacqueline A. I. Smith;Sonja Gamby

  • Fluorescence, Phosphorescence, and Chemiluminescence

    Noureen Siraj;Bilal El-Zahab;Suzana Hamdan;Tony E. Karam

  • Inhibition of innate immune cytosolic surveillance by an M. tuberculosis phosphodiesterase

    Ruchi Jain Dey;Ruchi Jain Dey;Bappaditya Dey;Bappaditya Dey;Bappaditya Dey;Yue Zheng;Yue Zheng;Yue Zheng;Laurene S Cheung

  • Evidence of link between quorum sensing and sugar metabolism in Escherichia coli revealed via cocrystal structures of LsrK and HPr

    Jung-Hye Ha;Pricila Hauk;Kun Cho;Yumi Eo

  • ENPP1, an Old Enzyme with New Functions, and Small Molecule Inhibitors-A STING in the Tale of ENPP1.

    Kenneth I. Onyedibe;Modi Wang;Herman O. Sintim

  • A noncarbohydrate based approach to polyhydroxylated pyrrolidizines: total syntheses of the natural products hyacinthacine A1 and 1-epiaustraline.

    Timothy J. Donohoe;Herman O. Sintim;Jackie Hollinshead

  • Junction probes - sequence specific detection of nucleic acids via template enhanced hybridization processes.

    Shizuka Nakayama;Lei Yan;Herman O. Sintim

  • Cyclic dinucleotide (c-di-GMP, c-di-AMP, and cGAMP) signalings have come of age to be inhibited by small molecules

    Clement Opoku-Temeng;Clement Opoku-Temeng;Jie Zhou;Yue Zheng;Yue Zheng;Jianmei Su

  • Evidence of magnetic isotope effects during thermochemical sulfate reduction

    Harry Oduro;Brian Harms;Herman O. Sintim;Alan J. Kaufman

  • Synthetic Analogs Tailor Native AI-2 Signaling Across Bacterial Species

    Varnika Roy;Jacqueline A I Smith;Jingxin Wang;Jessica E Stewart

  • The difluorotoluene debate--a decade later.

    Eric T. Kool;Herman O. Sintim

Frequent Co-Authors

William E. Bentley
William E. Bentley University of Maryland, College Park
Eija Könönen
Eija Könönen University of Turku
Mohamed N. Seleem
Mohamed N. Seleem Virginia Tech
Timothy J. Donohoe
Timothy J. Donohoe University of Oxford
Reza Ghodssi
Reza Ghodssi University of Maryland, College Park
Eric T. Kool
Eric T. Kool Stanford University
Stina Syrjänen
Stina Syrjänen University of Turku
William R. Bishai
William R. Bishai Johns Hopkins University
Isiah M. Warner
Isiah M. Warner Louisiana State University
Wenhao Hu
Wenhao Hu Sun Yat-sen University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students interested in applying their Chemistry knowledge in practical and impactful ways, pursuing related online degrees can open diverse career pathways. An online bachelor's degree in forensic science offers a strong foundation in chemical analysis techniques crucial for crime scene investigation and legal processes.

For those aiming to specialize further, an online master's in forensic psychology enables a unique blend of scientific and behavioral insights, supporting roles within criminal justice and mental health systems.

Career options in this field are varied and growing. Exploring forensic science career opportunities highlights roles ranging from lab analysts to expert witnesses, all of which rely heavily on chemical expertise combined with investigative skills.

When considering education investments, understanding how much is criminal justice school can provide clarity on tuition fees and overall costs, helping students make informed decisions about their academic journey.

Best Scientists Citing Herman O. Sintim

Trending Scientists