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Biology and Biochemistry

D-Index
59
Citations
11452
World Ranking
12642
National Ranking
900

Overview

Volkhard Kaever is affiliated with Hannover Medical School in Germany. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant contributions in medicine. The scientist's work spans several subfields including molecular biology, genetics, pulmonary and respiratory medicine, plant science, and organic chemistry.

Research topics covered by Kaever include:

  • Bacterial biofilms and quorum sensing
  • RNA and protein synthesis mechanisms
  • Bacterial genetics and biotechnology
  • Pneumonia and respiratory infections
  • Cystic fibrosis research advances
  • Plant pathogenic bacteria studies
  • RNA modifications and cancer

Frequent co-authors associated with Volkhard Kaever are:

  • Matthias Preuße
  • Mathias Müsken
  • Susanne Häußler
  • Heike Bähre
  • Maike Kuhn

Their publications have appeared in various scientific venues, with a focus on:

  • Proceedings of the National Academy of Sciences
  • npj Biofilms and Microbiomes
  • Circulation
  • PLoS Genetics
  • Environmental Microbiology

Examples of recent papers by Kaever include:

  • "Natural Compound Library Screening Identifies New Molecules for the Treatment of Cardiac Fibrosis and Diastolic Dysfunction," 2020, Circulation
  • "The alarmones (p)ppGpp are part of the heat shock response of Bacillus subtilis," 2020, PLoS Genetics
  • "Parallel evolutionary paths to produce more than one Pseudomonas aeruginosa biofilm phenotype," 2020, npj Biofilms and Microbiomes
  • "c-di-AMP hydrolysis by the phosphodiesterase AtaC promotes differentiation of multicellular bacteria," 2020, Proceedings of the National Academy of Sciences
  • "An extracytoplasmic protein and a moonlighting enzyme modulate synthesis of c-di-AMP in Listeria monocytogenes," 2020, Environmental Microbiology

Best Publications

  • c-di-AMP Is a New Second Messenger in Staphylococcus aureus with a Role in Controlling Cell Size and Envelope Stress.

    Rebecca M. Corrigan;James C. Abbott;Heike Burhenne;Volkhard Kaever

  • Second Messenger-Mediated Adjustment of Bacterial Swimming Velocity

    Alex Boehm;Matthias Kaiser;Hui Li;Christian Spangler

  • Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein.

    Steffen Baltes;Alexandra M. Gastens;Maren Fedrowitz;Heidrun Potschka

  • Viruses transfer the antiviral second messenger cGAMP between cells.

    A. Bridgeman;J. Maelfait;T. Davenne;T. Partridge

  • Quantification of antiretroviral drugs in dried blood spot samples by means of liquid chromatography/tandem mass spectrometry

    Therese Koal;Heike Burhenne;Regina Römling;Michal Svoboda

  • YfiBNR Mediates Cyclic di-GMP Dependent Small Colony Variant Formation and Persistence in Pseudomonas aeruginosa

    Jacob G. Malone;Tina Jaeger;Christian Spangler;Daniel Ritz

  • Cyclic di-AMP homeostasis in bacillus subtilis: both lack and high level accumulation of the nucleotide are detrimental for cell growth.

    Felix M.P. Mehne;Katrin Gunka;Hinnerk Eilers;Christina Herzberg

  • The Two Calcium-binding Proteins, S100A8 and S100A9, Are Involved in the Metabolism of Arachidonic acid in Human Neutrophils

    Claus Kerkhoff;Martin Klempt;Volkhard Kaever;Clemens Sorg

  • A liquid chromatography-coupled tandem mass spectrometry method for quantitation of cyclic di-guanosine monophosphate.

    Christian Spangler;Alex Böhm;Urs Jenal;Roland Seifert

  • Control of potassium homeostasis is an essential function of the second messenger cyclic di-AMP in Bacillus subtilis

    Jan Gundlach;Christina Herzberg;Volkhard Kaever;Katrin Gunka

  • cGAS Senses Human Cytomegalovirus and Induces Type I Interferon Responses in Human Monocyte-Derived Cells

    Jennifer Paijo;Marius Döring;Julia Spanier;Elena Grabski

  • Regulatory cohesion of cell cycle and cell differentiation through interlinked phosphorylation and second messenger networks.

    Sören Abel;Peter Chien;Paul Wassmann;Tilman Schirmer

  • Simultaneous determination of four immunosuppressants by means of high speed and robust on-line solid phase extraction–high performance liquid chromatography–tandem mass spectrometry

    Therese Koal;Michael Deters;Bruno Casetta;Volkhard Kaever

  • Functional expression of NADPH oxidase components (alpha- and beta-subunits of cytochrome b558 and 45-kDa flavoprotein) by intrinsic human glomerular mesangial cells.

    H. H. Radeke;A. R. Cross;J. T. Hancock;O. T. G. Jones

  • Cross-talk between Two Nucleotide-signaling Pathways in Staphylococcus aureus

    Rebecca M. Corrigan;Lisa Bowman;Alexandra R. Willis;Volkhard Kaever

  • An essential poison: Synthesis and degradation of cyclic di-AMP in Bacillus subtilis

    Jan Gundlach;Felix M. P. Mehne;Christina Herzberg;Jan Kampf

  • More than Enzymes That Make or Break Cyclic Di-GMP-Local Signaling in the Interactome of GGDEF/EAL Domain Proteins of Escherichia coli.

    Olga Sarenko;Gisela Klauck;Franziska M Wilke;Vanessa Pfiffer

  • Bi-modal Distribution of the Second Messenger c-di-GMP Controls Cell Fate and Asymmetry during the Caulobacter Cell Cycle

    Sören Abel;Tabitha Bucher;Micaël Nicollier;Isabelle Hug

  • Tigecycline possibly underdosed for the treatment of pneumonia: a pharmacokinetic viewpoint.

    Olaf Burkhardt;Kerstin Rauch;Volkhard Kaever;Johannes Hadem

  • Oligoribonuclease is a central feature of cyclic diguanylate signaling in Pseudomonas aeruginosa

    Dorit Cohen;Undine Mechold;Hadas Nevenzal;Yafit Yarmiyhu

Frequent Co-Authors

Klaus Resch
Klaus Resch Hannover Medical School
Roland Seifert
Roland Seifert Hannover Medical School
Jörg Stülke
Jörg Stülke University of Göttingen
Urs Jenal
Urs Jenal University of Basel
Jan T. Kielstein
Jan T. Kielstein Hannover Medical School
Susanne Häussler
Susanne Häussler Helmholtz Centre for Infection Research
Dara W. Frank
Dara W. Frank Medical College of Wisconsin
Angelika Gründling
Angelika Gründling Imperial College London
Michael Givskov
Michael Givskov University of Copenhagen
Anke Becker
Anke Becker Philipp University of Marburg

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