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Tim Tolker-Nielsen

Tim Tolker-Nielsen

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Microbiology
Denmark
2023

D-Index & Metrics

Microbiology

D-Index
86
Citations
31902
World Ranking
827
National Ranking
13

Research.com Recognitions

  • 2023 - Research.com Microbiology in Denmark Leader Award
  • 2022 - Research.com Microbiology in Denmark Leader Award

Overview

Tim Tolker-Nielsen is affiliated with the University of Copenhagen in Denmark. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a significant contribution to the study of bacterial biofilms and quorum sensing.

The scientist has published extensively in subfields including molecular biology, endocrinology, molecular medicine, microbiology, and genetics. Their work contributes to various specialized topics such as bacterial biofilms and quorum sensing, antibiotic resistance in bacteria, antimicrobial peptides and activities, bacterial genetics and biotechnology, research into Legionella and Acanthamoeba, advanced MEMS and NEMS technologies, and oral microbiology and periodontitis research.

Recent publications highlight the scope and emphasis of their research. These include:

  • "Immune Responses to Pseudomonas aeruginosa Biofilm Infections," 2021, Frontiers in Immunology
  • "The non-attached biofilm aggregate," 2023, Communications Biology
  • "Identification of small molecules that interfere with c-di-GMP signaling and induce dispersal of Pseudomonas aeruginosa biofilms," 2021, npj Biofilms and Microbiomes
  • "Miniature magneto-mechanical resonators for wireless tracking and sensing," 2023, Science
  • "A genetic switch controls Pseudomonas aeruginosa surface colonization," 2023, Nature Microbiology

Tim Tolker-Nielsen collaborates frequently with a group of co-authors, with notable repeated partnerships including:

  • Morten Rybtke
  • Michael Givskov
  • Jens Bo Andersen
  • Kasper Nørskov Kragh
  • Tim Holm Jakobsen

Their work has been published in various scientific venues, with frequent contributions to:

  • Zenodo (CERN European Organization for Nuclear Research)
  • Antimicrobial Agents and Chemotherapy
  • npj Biofilms and Microbiomes
  • Infection and Immunity
  • Biofilm

Best Publications

  • Extracellular DNA Required for Bacterial Biofilm Formation

    Cynthia Beth Whitchurch;Tim Tolker-Nielsen;Paula C Ragas;John S Mattick

  • Biofilm formation by Pseudomonas aeruginosa wild type, flagella and type IV pili mutants

    M. Klausen;Arne Heydorn;Paula Cornelia Ragas;Lotte Munch Lambertsen

  • A characterization of DNA release in Pseudomonas aeruginosa cultures and biofilms

    Marie Allesen‐Holm;Kim Bundvig Barken;Liang Yang;Mikkel Klausen

  • The clinical impact of bacterial biofilms

    Niels Høiby;Oana Ciofu;Helle Krogh Johansen;Zhi-jun Song

  • Gene transfer occurs with enhanced efficiency in biofilms and induces enhanced stabilisation of the biofilm structure

    Søren Molin;Tim Tolker-Nielsen

  • Cell Death in Pseudomonas aeruginosa Biofilm Development

    Jeremy S. Webb;Lyndal S. Thompson;Sally James;Tim Charlton

  • Tolerance and Resistance of Pseudomonas aeruginosa Biofilms to Antimicrobial Agents-How P. aeruginosa Can Escape Antibiotics

    Oana Ciofu;Tim Tolker-Nielsen

  • Involvement of bacterial migration in the development of complex multicellular structures in Pseudomonas aeruginosa biofilms.

    Mikkel Klausen;Anders Aaes-Jørgensen;Søren Molin;Tim Tolker-Nielsen

  • Distribution, Organization, and Ecology of Bacteria in Chronic Wounds

    Klaus Kirketerp-Møller;Peter Ø. Jensen;Mustafa Fazli;Kit G. Madsen

  • Role of autolysin-mediated DNA release in biofilm formation of Staphylococcus epidermidis

    Zhiqiang Qin;Yuanzhu Ou;Liang Yang;Yuli Zhu

  • Precision-engineering the Pseudomonas aeruginosa genome with two-step allelic exchange

    Laura R Hmelo;Bradley R Borlee;Henrik Almblad;Michelle E Love

  • Tolerance to the antimicrobial peptide colistin in Pseudomonas aeruginosa biofilms is linked to metabolically active cells, and depends on the pmr and mexAB‐oprM genes

    Sünje Johanna Pamp;Morten Gjermansen;Helle Krogh Johansen;Tim Tolker-Nielsen

  • Nonrandom Distribution of Pseudomonas aeruginosa and Staphylococcus aureus in Chronic Wounds

    Mustafa Fazli;Thomas Bjarnsholt;Klaus Kirketerp-Møller;Bo Jørgensen

  • Biofilms in chronic infections – a matter of opportunity – monospecies biofilms in multispecies infections

    Mette Burmølle;Trine Rolighed Thomsen;Mustafa Fazli;Irene Dige

  • Roles of type IV pili, flagellum-mediated motility and extracellular DNA in the formation of mature multicellular structures in Pseudomonas aeruginosa biofilms.

    Kim B Barken;Sunje J Pamp;Liang Yang;Morten Gjermansen

  • Development and dynamics of Pseudomonas sp. biofilms.

    Tim Tolker-Nielsen;Ulla C. Brinch;Paula C. Ragas;Jens Bo Andersen

  • An update on Pseudomonas aeruginosa biofilm formation, tolerance, and dispersal

    Morten Harmsen;Liang Yang;Sünje Johanna Pamp;Tim Tolker-Nielsen

  • Multiple Roles of Biosurfactants in Structural Biofilm Development by Pseudomonas aeruginosa

    Sünje Johanna Pamp;Tim Tolker-Nielsen

  • Effects of Antibiotics on Quorum Sensing in Pseudomonas aeruginosa

    Mette E. Skindersoe;Morten Alhede;Richard Phipps;Liang Yang

  • Dispersed cells represent a distinct stage in the transition from bacterial biofilm to planktonic lifestyles.

    Song Lin Chua;Yang Liu;Joey Kuok Hoong Yam;Yicai Chen

  • Statistical analysis of Pseudomonas aeruginosa biofilm development: impact of mutations in genes involved in twitching motility, cell-to-cell signaling, and stationary-phase sigma factor expression.

    Arne Heydorn;Bjarne Kjær Ersbøll;Junichi Kato;Morten Hentzer

Frequent Co-Authors

Michael Givskov
Michael Givskov University of Copenhagen
Liang Yang
Liang Yang Southern University of Science and Technology
Søren Molin
Søren Molin Technical University of Denmark
Thomas Bjarnsholt
Thomas Bjarnsholt University of Copenhagen
Niels Høiby
Niels Høiby University of Copenhagen
Peter Østrup Jensen
Peter Østrup Jensen University of Copenhagen
Staffan Kjelleberg
Staffan Kjelleberg Nanyang Technological University
Matthew R. Parsek
Matthew R. Parsek University of Washington
Oana Ciofu
Oana Ciofu University of Copenhagen
Leo Eberl
Leo Eberl University of Zurich

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