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Microbiology

D-Index
95
Citations
49386
World Ranking
528
National Ranking
245

Overview

Matthew R. Parsek is affiliated with the University of Washington in the United States. Their research primarily focuses on the intersections of biochemistry, genetics, and molecular biology, with a total of 68 publications in these fields. This body of work extends into specialized subfields such as molecular biology, genetics, periodontics, pulmonary and respiratory medicine, and plant science.

The main topics addressed in Parsek's research include bacterial biofilms and quorum sensing, bacterial genetics and biotechnology, oral microbiology and periodontitis research, cystic fibrosis research advances, antibiotic resistance in bacteria, Vibrio bacteria research studies, and microbial community ecology and physiology.

Scientific publications by Parsek appear frequently in specific venues. The most common platforms for their work are the Journal of Bacteriology, with nine publications, followed by mBio with four, Proceedings of the National Academy of Sciences with three, Communications Biology with two, and FEMS Microbiology Reviews with two.

Recent notable papers by Parsek include:

  • Pseudomonas aeruginosa aggregates in cystic fibrosis sputum produce exopolysaccharides that likely impede current therapies, 2021, Cell Reports
  • The Versatile Pseudomonas aeruginosa Biofilm Matrix Protein CdrA Promotes Aggregation through Different Extracellular Exopolysaccharide Interactions, 2020, Journal of Bacteriology
  • Elevated exopolysaccharide levels in Pseudomonas aeruginosa flagellar mutants have implications for biofilm growth and chronic infections, 2020, PLoS Genetics
  • Social Cooperativity of Bacteria during Reversible Surface Attachment in Young Biofilms: a Quantitative Comparison of Pseudomonas aeruginosa PA14 and PAO1, 2020, mBio
  • Bacterial cyclic diguanylate signaling networks sense temperature, 2021, Nature Communications

Frequent collaborators in Parsek's research include:

  • Daniel J. Wozniak
  • P. Lynne Howell
  • Courtney Reichhardt
  • Joe J. Harrison
  • Holly M. Jacobs

Best Publications

  • The involvement of cell-to-cell signals in the development of a bacterial biofilm

    David G. Davies;Matthew R. Parsek;Matthew R. Parsek;Matthew R. Parsek;James P. Pearson;James P. Pearson;James P. Pearson;Barbara H. Iglewski;Barbara H. Iglewski;Barbara H. Iglewski

  • Bacterial competition: surviving and thriving in the microbial jungle

    Michael E. Hibbing;Clay Fuqua;Matthew R. Parsek;S. Brook Peterson

  • Bacterial Biofilms: An Emerging Link to Disease Pathogenesis

    Matthew R. Parsek;Pradeep K. Singh

  • Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms

    Pradeep K. Singh;Amy L. Schaefer;Matthew R. Parsek;Thomas O. Moninger

  • Regulation of Gene Expression by Cell-to-Cell Communication: Acyl-Homoserine Lactone Quorum Sensing

    C Fuqua;M R Parsek;E P Greenberg

  • Gene expression in Pseudomonas aeruginosa biofilms

    Marvin Whiteley;M. Gita Bangera;Roger E. Bumgarner;Matthew R. Parsek

  • Sociomicrobiology: the connections between quorum sensing and biofilms

    Matthew R. Parsek;E.P. Greenberg

  • A component of innate immunity prevents bacterial biofilm development

    Pradeep K. Singh;Matthew R. Parsek;E. Peter Greenberg;E. Peter Greenberg;Michael J. Welsh;Michael J. Welsh;Michael J. Welsh

  • Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound.

    Morten Hentzer;Kathrin Riedel;Thomas B. Rasmussen;Arne Heydorn

  • Interaction and signalling between a cosmopolitan phytoplankton and associated bacteria

    S. A. Amin;L. R. Hmelo;H. M. van Tol;B. P. Durham

  • Acyl-homoserine lactone quorum sensing in Gram-negative bacteria: A signaling mechanism involved in associations with higher organisms

    Matthew R. Parsek;E. Peter Greenberg

  • Heavy metal resistance of biofilm and planktonic Pseudomonas aeruginosa.

    Gail M. Teitzel;Matthew R. Parsek

  • Alginate Overproduction Affects Pseudomonas aeruginosa Biofilm Structure and Function

    Morten Hentzer;Gail M. Teitzel;Grant J. Balzer;Arne Heydorn

  • Assembly and development of the Pseudomonas aeruginosa biofilm matrix.

    Luyan Z. Ma;Matthew Conover;Haiping Lu;Matthew R. Parsek

  • Acyl homoserine-lactone quorum-sensing signal generation

    Matthew R. Parsek;Dale L. Val;Brian L. Hanzelka;John E. Cronan

  • Pseudomonas aeruginosa Anaerobic Respiration in Biofilms: Relationships to Cystic Fibrosis Pathogenesis

    Sang Sun Yoon;Robert F. Hennigan;George M. Hilliard;Urs A. Ochsner

  • The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional

    Joshua D. Shrout;David L. Chopp;Collin L. Just;Morten Hentzer

  • The Pel and Psl polysaccharides provide Pseudomonas aeruginosa structural redundancy within the biofilm matrix

    Kelly M. Colvin;Yasuhiko Irie;Catherine S. Tart;Rodolfo Urbano

  • The Exopolysaccharide Alginate Protects Pseudomonas aeruginosa Biofilm Bacteria from IFN-γ-Mediated Macrophage Killing

    Jeff G. Leid;Carey J. Willson;Mark E. Shirtliff;Daniel J. Hassett

  • Pseudomonas aeruginosa uses a cyclic-di-GMP-regulated adhesin to reinforce the biofilm extracellular matrix

    Bradley R. Borlee;Aaron D. Goldman;Keiji Murakami;Ram Samudrala

  • The Pel Polysaccharide Can Serve a Structural and Protective Role in the Biofilm Matrix of Pseudomonas aeruginosa

    Kelly M. Colvin;Vernita D. Gordon;Keiji Murakami;Bradley R. Borlee

Frequent Co-Authors

Daniel J. Wozniak
Daniel J. Wozniak The Ohio State University
Joe J. Harrison
Joe J. Harrison University of Calgary
Michael Givskov
Michael Givskov University of Copenhagen
E. P. Greenberg
E. P. Greenberg University of Washington
P. Lynne Howell
P. Lynne Howell University of Toronto
Clay Fuqua
Clay Fuqua Indiana University
Pradeep K. Singh
Pradeep K. Singh University of Washington
Lucas R. Hoffman
Lucas R. Hoffman University of Washington
Tim Tolker-Nielsen
Tim Tolker-Nielsen University of Copenhagen
Donald C. Sheppard
Donald C. Sheppard McGill University

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