His primary areas of investigation include Bacteria, Microbiology, Pseudomonas aeruginosa, Biofilm and Cystic fibrosis. His study in Microbiology focuses on Antimicrobial in particular. The Pseudomonas aeruginosa study combines topics in areas such as Ciprofloxacin and Multidrug tolerance.
His work deals with themes such as Chronic infection, Penetration, Antibiotics and Genetic diversity, which intersect with Biofilm. Pradeep K. Singh interconnects Lung, Immunology, Pathogenesis and Virulence in the investigation of issues within Cystic fibrosis. His work in the fields of Immunology, such as Cytokine, intersects with other areas such as Adipose tissue macrophages.
His main research concerns Microbiology, Pseudomonas aeruginosa, Cystic fibrosis, Biofilm and Bacteria. His Microbiology research incorporates themes from Chronic infection, Innate immune system and Host. In his research, Pathogen is intimately related to Virulence, which falls under the overarching field of Pseudomonas aeruginosa.
His Cystic fibrosis research is multidisciplinary, relying on both Sputum, Lung and Immunology. His work is dedicated to discovering how Biofilm, Filamentous bacteriophage are connected with Inovirus and other disciplines. His biological study spans a wide range of topics, including Adaptation and Extracellular.
Pradeep K. Singh spends much of his time researching Cystic fibrosis, Microbiology, Pseudomonas aeruginosa, Ivacaftor and Internal medicine. His Cystic fibrosis study combines topics from a wide range of disciplines, such as Microbiome, Microbiological culture, Sputum and Lung. Pradeep K. Singh works on Microbiology which deals in particular with Pathogen.
The various areas that he examines in his Pseudomonas aeruginosa study include In vitro, Typing and In vivo. His studies in Virulence integrate themes in fields like Pathogenesis, Biofilm, Genetic Fitness, Host and Chronic infection. His Prevotella research is under the purview of Bacteria.
Pradeep K. Singh mainly focuses on Cystic fibrosis, Microbiology, Sputum, Pathogen and Pseudomonas aeruginosa. His Cystic fibrosis research integrates issues from Prevotella and Proteome. His Microbiology research incorporates elements of Biofilm, Genetic Fitness, Chronic wound, Chronic infection and Virulence.
His study in Sputum is interdisciplinary in nature, drawing from both Outpatient clinic, Immunology, Sepsis, Microbiological culture and Blood plasma. He has researched Pathogen in several fields, including Microbiome, Streptococcus, Veillonella, Bacteria and Lung. His Pseudomonas aeruginosa research is multidisciplinary, incorporating perspectives in Receptor, In vitro, Pathogenesis and In vivo.
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Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms
Pradeep K. Singh;Amy L. Schaefer;Matthew R. Parsek;Thomas O. Moninger.
Nature (2000)
Bacterial Biofilms: An Emerging Link to Disease Pathogenesis
Matthew R. Parsek;Pradeep K. Singh.
Annual Review of Microbiology (2003)
A component of innate immunity prevents bacterial biofilm development
Pradeep K. Singh;Matthew R. Parsek;E. Peter Greenberg;E. Peter Greenberg;Michael J. Welsh;Michael J. Welsh;Michael J. Welsh.
Nature (2002)
Active Starvation Responses Mediate Antibiotic Tolerance in Biofilms and Nutrient-Limited Bacteria
Dao Nguyen;Amruta Joshi-Datar;Francois Lepine;Elizabeth Bauerle.
Science (2011)
Self-generated diversity produces “insurance effects” in biofilm communities
Blaise R. Boles;Matthew Thoendel;Pradeep K. Singh.
Proceedings of the National Academy of Sciences of the United States of America (2004)
Production of β-defensins by human airway epithelia
Pradeep K. Singh;Hong Peng Jia;Kerry Wiles;Jay Hesselberth.
Proceedings of the National Academy of Sciences of the United States of America (1998)
The transition metal gallium disrupts Pseudomonas aeruginosa iron metabolism and has antimicrobial and antibiofilm activity
Yukihiro Kaneko;Matthew Thoendel;Oyebode Olakanmi;Bradley E. Britigan.
Journal of Clinical Investigation (2007)
Metabolic dysfunction drives a mechanistically distinct proinflammatory phenotype in adipose tissue macrophages.
Mario Kratz;Mario Kratz;Brittney R. Coats;Katherine B. Hisert;Derek Hagman.
Cell Metabolism (2014)
Rhamnolipids mediate detachment of Pseudomonas aeruginosa from biofilms.
Blaise R. Boles;Matthew Thoendel;Pradeep K. Singh.
Molecular Microbiology (2005)
Cystic Fibrosis Sputum Supports Growth and Cues Key Aspects of Pseudomonas aeruginosa Physiology
Kelli L. Palmer;Lauren M. Mashburn;Pradeep K. Singh;Marvin Whiteley.
Journal of Bacteriology (2005)
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