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George A. O'Toole

George A. O'Toole

D-Index & Metrics

Microbiology

D-Index
96
Citations
56158
World Ranking
489
National Ranking
228

Research.com Recognitions

  • 2011 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

George A. O'Toole is affiliated with Dartmouth College in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant contributions to medicine. Major subfields of study include molecular biology, pulmonary and respiratory medicine, genetics, ecology, and epidemiology.

Their notable research areas include bacterial biofilms and quorum sensing, cystic fibrosis research advances, bacterial genetics and biotechnology, gut microbiota and health, biochemical and structural characterization, microbial community ecology and physiology, and antibiotic resistance in bacteria.

Frequent coauthors working alongside George A. O'Toole are:

  • Kaitlyn E. Barrack
  • Gerard C. L. Wong
  • Shanice S. Webster
  • Alexander J. McAdam
  • Ira J. Blader

Publications by George A. O'Toole have appeared extensively in leading scientific venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory) with 40 publications
  • Journal of Bacteriology with 34 publications
  • mBio with 11 publications
  • Microbiology Spectrum with 6 publications
  • Proceedings of the National Academy of Sciences with 4 publications

Some recent papers authored or coauthored by George A. O'Toole are:

  • "Lung function and microbiota diversity in cystic fibrosis", 2020, Microbiome
  • "Roadmap on emerging concepts in the physical biology of bacterial biofilms: from surface sensing to community formation", 2021, Physical Biology
  • "From Input to Output: The Lap/c-di-GMP Biofilm Regulatory Circuit", 2020, Annual Review of Microbiology
  • "Social Cooperativity of Bacteria during Reversible Surface Attachment in Young Biofilms: a Quantitative Comparison of Pseudomonas aeruginosa PA14 and PAO1", 2020, mBio
  • "Community composition shapes microbial-specific phenotypes in a cystic fibrosis polymicrobial model system", 2023, eLife

George A. O'Toole was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2011.

Best Publications

  • Mechanisms of biofilm resistance to antimicrobial agents

    Thien Fah C. Mah;George A. O'Toole

  • Biofilm Formation as Microbial Development

    George O'Toole;Heidi B. Kaplan;Roberto Kolter

  • Microbial Biofilms: from Ecology to Molecular Genetics

    Mary Ellen Davey;George A. O'toole

  • Flagellar and twitching motility are necessary for Pseudomonas aeruginosa biofilm development

    George A. O'Toole;Roberto Kolter

  • Initiation of biofilm formation in Pseudomonas fluorescens WCS365 proceeds via multiple, convergent signalling pathways: a genetic analysis

    George A. O'Toole;Roberto Kolter

  • Microtiter dish biofilm formation assay.

    George A. O'Toole

  • A genetic basis for Pseudomonas aeruginosa biofilm antibiotic resistance

    Thien-Fah Mah;Betsey Pitts;Brett Pellock;Brett Pellock;Graham C. Walker

  • Growing and analyzing static biofilms

    Judith H. Merritt;Daniel E. Kadouri;George A. O'Toole

  • GENETIC APPROACHES TO STUDY OF BIOFILMS

    George A. O'Toole;Leslie A. Pratt;Paula I. Watnick;Dianne K. Newman

  • Rhamnolipid surfactant production affects biofilm architecture in Pseudomonas aeruginosa PAO1.

    Mary E. Davey;Nicky C. Caiazza;George A. O'Toole

  • The developmental model of microbial biofilms: ten years of a paradigm up for review.

    Russell D. Monds;George A. O’Toole

  • Long-Distance Delivery of Bacterial Virulence Factors by Pseudomonas aeruginosa Outer Membrane Vesicles

    Jennifer M. Bomberger;Daniel P. MacEachran;Bonita A. Coutermarsh;Siying Ye

  • Transition from reversible to irreversible attachment during biofilm formation by Pseudomonas fluorescens WCS365 requires an ABC transporter and a large secreted protein.

    Shannon M. Hinsa;Manuel Espinosa-Urgel;Juan L. Ramos;George A. O'Toole

  • Innate and induced resistance mechanisms of bacterial biofilms.

    G. G. Anderson;G. A. O'Toole

  • Alginate is not a significant component of the extracellular polysaccharide matrix of PA14 and PAO1 Pseudomonas aeruginosa biofilms.

    Daniel J. Wozniak;Timna J. O. Wyckoff;Melissa Starkey;Rebecca Keyser

  • Rhamnolipids Modulate Swarming Motility Patterns of Pseudomonas aeruginosa

    Nicky C. Caiazza;Robert M. Q. Shanks;G. A. O'Toole

  • Saccharomyces cerevisiae-Based Molecular Tool Kit for Manipulation of Genes from Gram-Negative Bacteria

    Robert M. Q. Shanks;Nicky C. Caiazza;Shannon M. Hinsa;Christine M. Toutain

  • BifA, a cyclic-Di-GMP phosphodiesterase, inversely regulates biofilm formation and swarming motility by Pseudomonas aeruginosa PA14.

    Sherry L. Kuchma;Judith H. Merritt;Nicole T. Liberati

  • Pseudomonas aeruginosa biofilm formation in the cystic fibrosis airway.

    Sophie Moreau-Marquis;Bruce A. Stanton;George A. O’Toole

  • The Global Carbon Metabolism Regulator Crc Is a Component of a Signal Transduction Pathway Required for Biofilm Development by Pseudomonas aeruginosa

    George A. O'Toole;George A. O'Toole;Karine A. Gibbs;Paul W. Hager;Paul V. Phibbs

Frequent Co-Authors

Bruce A. Stanton
Bruce A. Stanton Dartmouth College
Deborah A. Hogan
Deborah A. Hogan Dartmouth College
Holger Sondermann
Holger Sondermann Kiel University
Robert M. Q. Shanks
Robert M. Q. Shanks University of Pittsburgh
Michael A. Henson
Michael A. Henson University of Chicago
Hilary G. Morrison
Hilary G. Morrison Marine Biological Laboratory
Mitchell L. Sogin
Mitchell L. Sogin Marine Biological Laboratory
Ambrose L. Cheung
Ambrose L. Cheung Dartmouth College
Mark W. Grinstaff
Mark W. Grinstaff Boston University
Roberto Kolter
Roberto Kolter Harvard University

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