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Ambrose L. Cheung

Ambrose L. Cheung

D-Index & Metrics

Microbiology

D-Index
91
Citations
22031
World Ranking
667
National Ranking
311

Research.com Recognitions

  • 2007 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Ambrose L. Cheung is affiliated with Dartmouth College in the United States and has an extensive research portfolio primarily focused on antimicrobial resistance and bacterial pathogenesis. Their work intersects medicine, biochemistry, genetics, and molecular biology, with significant contributions in infectious diseases and molecular medicine.

The scientist's research centers on topics including:

  • Antimicrobial Resistance in Staphylococcus
  • Bacterial biofilms and quorum sensing
  • Antibiotic Resistance in Bacteria
  • Antimicrobial Peptides and Activities
  • Bacterial Genetics and Biotechnology
  • Infective Endocarditis Diagnosis and Management
  • Bacterial Identification and Susceptibility Testing

Among their recent publications are:

  • "Expanding the Staphylococcus aureus SarA Regulon to Small RNAs," 2021, mSystems
  • "The extracellular loop of the membrane permease VraG interacts with GraS to sense cationic antimicrobial peptides in Staphylococcus aureus," 2021, PLoS Pathogens
  • "The Stringent Response Contributes to Persistent Methicillin-Resistant Staphylococcus aureus Endovascular Infection Through the Purine Biosynthetic Pathway," 2020, The Journal of Infectious Diseases
  • "Teg58, a small regulatory RNA, is involved in regulating arginine biosynthesis and biofilm formation in Staphylococcus aureus," 2022, Scientific Reports
  • "The Staphylococcus aureus toxin-antitoxin system YefM-YoeB is associated with antibiotic tolerance and extracellular dependent biofilm formation," 2021, Journal of Bone and Joint Infection

They frequently publish in several scientific journals, including:

  • Microbiology Spectrum
  • mSystems
  • The Journal of Infectious Diseases
  • Journal of Medicinal Chemistry
  • PLoS Pathogens

Collaborations form an important part of their research, with frequent coauthors such as:

  • Adhar C. Manna
  • Arnold S. Bayer
  • Richard A. Proctor
  • Junho Cho
  • Yan Q. Xiong

Their work contributes primarily to the understanding of antimicrobial resistance mechanisms in Staphylococcus species, investigating genetic regulation, bacterial biofilm formation, and interactions with antimicrobial peptides. The research also extends to the study of infectious disease processes, including persistent infections caused by methicillin-resistant Staphylococcus aureus (MRSA).

Ambrose L. Cheung's contributions have been recognized through honors such as being named a Fellow of the American Association for the Advancement of Science (AAAS) in 2007.

Best Publications

  • Faculty Opinions recommendation of Evolution of MRSA during hospital transmission and intercontinental spread.

    Unknown

  • IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice

    John S. Cho;Eric M. Pietras;Nairy C. Garcia;Romela Irene Ramos

  • Persister formation in Staphylococcus aureus is associated with ATP depletion.

    Brian P. Conlon;Sarah E. Rowe;Autumn Brown Gandt;Austin S. Nuxoll

  • Regulation of virulence determinants in vitro and in vivo in Staphylococcus aureus

    Ambrose L Cheung;Arnold S Bayer;Arnold S Bayer;Gongyi Zhang;Hattie Gresham

  • Survival of Staphylococcus aureus inside neutrophils contributes to infection.

    Hattie D. Gresham;Jon H. Lowrance;Tony E. Caver;Bridget S. Wilson

  • Staphylococcus aureus protein A induces airway epithelial inflammatory responses by activating TNFR1.

    Marisa I Gómez;Aram Lee;Bharat Reddy;Amanda Muir

  • MyD88 Mediates Neutrophil Recruitment Initiated by IL-1R but Not TLR2 Activation in Immunity against Staphylococcus aureus

    Lloyd S. Miller;Ryan M. O'Connell;Miguel A. Gutierrez;Eric M. Pietras

  • Selective Chemical Inhibition of agr Quorum Sensing in Staphylococcus aureus Promotes Host Defense with Minimal Impact on Resistance

    Erin K. Sully;Natalia Malachowa;Bradley O. Elmore;Susan M. Alexander

  • Inflammasome-mediated production of IL-1β is required for neutrophil recruitment against Staphylococcus aureus in vivo

    Lloyd S. Miller;Eric M. Pietras;Lawrence H. Uricchio;Kathleen Hirano

  • Interconnections between Sigma B, agr, and proteolytic activity in Staphylococcus aureus biofilm maturation

    Katherine J. Lauderdale;Blaise R. Boles;Ambrose L. Cheung;Alexander R. Horswill

  • Heparin Stimulates Staphylococcus aureus Biofilm Formation

    Robert M. Q. Shanks;Niles P. Donegan;Martha L. Graber;Sarah E. Buckingham

  • Molecular basis of resistance to muramidase and cationic antimicrobial peptide activity of lysozyme in staphylococci.

    Silvia Herbert;Agnieszka Bera;Christiane Nerz;Dirk Kraus

  • Dynamics of Neutrophil Infiltration during Cutaneous Wound Healing and Infection Using Fluorescence Imaging

    Min Ho Kim;Wei Liu;Dori L Borjesson;Fitz Roy E Curry

  • Interaction of the GraRS Two-Component System with the VraFG ABC Transporter To Support Vancomycin-Intermediate Resistance in Staphylococcus aureus

    Michael Meehl;Silvia Herbert;Friedrich Götz;Ambrose Cheung

  • SarA, a Global Regulator of Virulence Determinants inStaphylococcus aureus, Binds to a Conserved Motif Essential for sar-dependent Gene Regulation*

    Unknown

  • The SarA protein family of Staphylococcus aureus

    Ambrose L. Cheung;Koren A. Nishina;Maria Pilar Trotonda;Sandeep Tamber

  • Whole-Genome Sequencing of Staphylococcus aureus Strain RN4220, a Key Laboratory Strain Used in Virulence Research, Identifies Mutations That Affect Not Only Virulence Factors but Also the Fitness of the Strain

    Dhanalakshmi Nair;Guido Memmi;David Hernandez;Jonathan Bard

  • Neutrophil-derived IL-1β Is Sufficient for Abscess Formation in Immunity against Staphylococcus aureus in Mice

    John S. Cho;Yi Guo;Romela Irene Ramos;Frank Hebroni

  • Quorum sensing between bacterial species on the skin protects against epidermal injury in atopic dermatitis

    Michael R. Williams;Stephen K. Costa;Livia S. Zaramela;Shadi Khalil

  • Confinement-induced quorum sensing of individual Staphylococcus aureus bacteria

    Eric C Carnes;DeAnna M Lopez;Niles P Donegan;Ambrose Cheung

  • Staphylococcus aureus RN6390 Replicates and Induces Apoptosis in a Pulmonary Epithelial Cell Line

    Barbara C. Kahl;Mark Goulian;Willem van Wamel;Mathias Herrmann

  • A Mouse Model of Post-Arthroplasty Staphylococcus aureus Joint Infection to Evaluate In Vivo the Efficacy of Antimicrobial Implant Coatings

    Nicholas M. Bernthal;Alexandra I. Stavrakis;Fabrizio Billi;John S. Cho

  • IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection

    John Cho;Eric Pietras;Nairy Garcia;Romela Irene Ramos

Frequent Co-Authors

Arnold S. Bayer
Arnold S. Bayer University of California, Los Angeles
Yan Q. Xiong
Yan Q. Xiong University of California, Los Angeles
Michael R. Yeaman
Michael R. Yeaman University of California, Los Angeles
Lloyd S. Miller
Lloyd S. Miller Johns Hopkins University
Genhong Cheng
Genhong Cheng University of California, Los Angeles
Robert L. Modlin
Robert L. Modlin University of California, Los Angeles
Remy Loris
Remy Loris Vrije Universiteit Brussel
Yoichiro Iwakura
Yoichiro Iwakura Tokyo University of Science
Scott I. Simon
Scott I. Simon University of California, Davis
George A. O'Toole
George A. O'Toole Dartmouth College

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