World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
58
Citations
13431
World Ranking
3399
National Ranking
1340

Overview

Mark S. Smeltzer is affiliated with the University of Arkansas for Medical Sciences in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on Surgery, Molecular Biology, Infectious Diseases, Public Health, Environmental and Occupational Health, and Organic Chemistry.

Their scholarly work addresses key topics such as antimicrobial resistance in Staphylococcus, orthopedic infections and treatments, bacterial biofilms and quorum sensing, orthopaedic implants and arthroplasty, streptococcal infections and treatments, surgical site infection prevention, and inflammasome and immune disorders.

Notable recent publications include:

  • Pyroptosis and pyroptosis-inducing cancer drugs, 2022, Acta Pharmacologica Sinica
  • SarA plays a predominant role in controlling the production of extracellular proteases in the diverse clinical isolates of Staphylococcus aureus LAC and UAMS-1, 2020, Virulence
  • 4-4-(Anilinomethyl)-3-[4-(trifluoromethyl)phenyl]-1H-pyrazol-1-ylbenzoic acid derivatives as potent anti-gram-positive bacterial agents, 2021, European Journal of Medicinal Chemistry
  • Evaluation of a bone filler scaffold for local antibiotic delivery to prevent Staphylococcus aureus infection in a contaminated bone defect, 2021, Scientific Reports
  • Limiting protease production plays a key role in the pathogenesis of the divergent clinical isolates of Staphylococcus aureus LAC and UAMS-1, 2021, Virulence

Their work is frequently published in venues such as Virulence, Infection and Immunity, Microorganisms, bioRxiv (Cold Spring Harbor Laboratory), and Acta Pharmacologica Sinica.

Collaboration is a notable aspect of their research career. Frequent coauthors include Karen E. Beenken, Mara J. Campbell, Aura M. Ramírez, Christopher M. Walker, and Daniel G. Meeker.

In addition to journal articles, they have contributed to book publications, including a title published by Frontiers Media: Biofilm-biomaterial interactions: understanding, preventing, and eradicating attachment in infection (2022).

Best Publications

  • The cidA murein hydrolase regulator contributes to DNA release and biofilm development in Staphylococcus aureus.

    Kelly C. Rice;Ethan E. Mann;Jennifer L. Endres;Elizabeth C. Weiss

  • Global Gene Expression in Staphylococcus aureus Biofilms

    Karen E. Beenken;Paul M. Dunman;Fionnuala McAleese;Daphne Macapagal

  • Photothermal Nanotherapeutics and Nanodiagnostics for Selective Killing of Bacteria Targeted with Gold Nanoparticles

    Vladimir P. Zharov;Kelly E. Mercer;Elena N. Galitovskaya;Mark S. Smeltzer

  • Modulation of eDNA release and degradation affects Staphylococcus aureus biofilm maturation.

    Ethan E. Mann;Kelly C. Rice;Blaise R. Boles;Jennifer L. Endres

  • Mutation of sarA in Staphylococcus aureus limits biofilm formation.

    Karen E. Beenken;Jon S. Blevins;Mark S. Smeltzer

  • Role of the accessory gene regulator (agr) in pathogenesis of staphylococcal osteomyelitis.

    A. F. Gillaspy;S. G. Hickmon;R. A.F Skinner;J. R. Thomas

  • Nuclease Modulates Biofilm Formation in Community-Associated Methicillin-Resistant Staphylococcus aureus

    Megan R. Kiedrowski;Jeffrey S. Kavanaugh;Cheryl L. Malone;Joe M. Mootz

  • Multiplex PCR Protocol for the Diagnosis of Staphylococcal Infection

    William J. Mason;Jon S. Blevins;Karen Beenken;Noroyono Wibowo

  • Characterization of a rabbit model of staphylococcal osteomyelitis

    Mark S. Smeltzer;J. Roby Thomas;Sandra G. Hickraon;Robert A. Skinner

  • A Secreted Bacterial Protease Tailors the Staphylococcus aureus Virulence Repertoire to Modulate Bone Remodeling during Osteomyelitis

    James E. Cassat;Neal D. Hammer;J. Preston Campbell;Meredith A. Benson

  • Staphylococcus aureus AgrA Binding to the RNAIII-agr Regulatory Region

    Robbin L. Koenig;Jessica L. Ray;Soheila J. Maleki;Mark S. Smeltzer

  • Strain-Dependent Differences in the Regulatory Roles of sarA and agr in Staphylococcus aureus

    Jon S. Blevins;Karen E. Beenken;Mohamed O. Elasri;Barry K. Hurlburt;Barry K. Hurlburt

  • Ellagic Acid Derivatives from Rubus ulmifolius Inhibit Staphylococcus aureus Biofilm Formation and Improve Response to Antibiotics

    Cassandra L. Quave;Miriam Estévez-Carmona;Miriam Estévez-Carmona;Cesar M. Compadre;Gerren Hobby

  • Mechanisms of Staphylococcus aureus invasion of cultured osteoblasts.

    John K. Ellington;Sheila S. Reilly;Sheila S. Reilly;Warren K. Ramp;Warren K. Ramp;Mark S. Smeltzer

  • Development of a Novel, Highly Quantitative In Vivo Model for the Study of Biofilm-Impaired Cutaneous Wound Healing

    Anandev N. Gurjala;Matthew R. Geringer;Akhil K. Seth;Seok J. Hong

  • Is aseptic loosening truly aseptic

    Carl L Nelson;Alex C McLaren;Sandra G McLaren;Jeffrey W Johnson

  • Epistatic relationships between sarA and agr in Staphylococcus aureus biofilm formation.

    Karen E. Beenken;Lara N. Mrak;Linda M. Griffin;Agnieszka K. Zielinska

  • The treatment of experimental osteomyelitis by surgical debridement and the implantation of calcium sulfate tobramycin pellets.

    Carl L. Nelson;Sandra G. McLaren;Robert A. Skinner;Mark S. Smeltzer

  • Transcriptional profiling of a Staphylococcus aureus clinical isolate and its isogenic agr and sarA mutants reveals global differences in comparison to the laboratory strain RN6390

    James Cassat;Paul M. Dunman;Ellen Murphy;Steven J. Projan

  • 2018 international consensus meeting on musculoskeletal infection: Summary from the biofilm workgroup and consensus on biofilm related musculoskeletal infections.

    Kordo Saeed;Alex C. McLaren;Edward M. Schwarz;Valentin Antoci

  • Synergistic Photothermal and Antibiotic Killing of Biofilm-Associated Staphylococcus aureus Using Targeted Antibiotic-Loaded Gold Nanoconstructs

    Daniel G. Meeker;Samir V. Jenkins;Emily K. Miller;Karen E. Beenken

Frequent Co-Authors

Paul M. Dunman
Paul M. Dunman University of Rochester
Alexander R. Horswill
Alexander R. Horswill University of Colorado Anschutz Medical Campus
Jingyi Chen
Jingyi Chen University of Arkansas at Fayetteville
Kenneth W. Bayles
Kenneth W. Bayles University of Nebraska Medical Center
Alan J. Tackett
Alan J. Tackett University of Arkansas for Medical Sciences
Steven J. Projan
Steven J. Projan Rutgers, The State University of New Jersey
Joel D. Bumgardner
Joel D. Bumgardner University of Memphis
Mark E. Shirtliff
Mark E. Shirtliff University of Maryland, Baltimore
Eric P. Skaar
Eric P. Skaar Vanderbilt University Medical Center
Alexandru S. Biris
Alexandru S. Biris University of Arkansas at Little Rock

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