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D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
10771
World Ranking
13310
National Ranking
5662

Overview

Bo R. Rueda is affiliated with Massachusetts General Hospital in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant contributions to medicine. They have published extensively in the fields of molecular biology, oncology, immunology, reproductive medicine, and cancer research.

The scientist's research covers a range of topics including ovarian cancer diagnosis and treatment, monoclonal and polyclonal antibodies, extracellular vesicles in disease, galectins and cancer biology, glycosylation and glycoproteins, CAR-T cell therapy research, and cancer-related molecular pathways.

Bo R. Rueda has published papers in several prominent journals, including:

  • Enhanced Efficacy of Simultaneous PD-1 and PD-L1 Immune Checkpoint Blockade in High-Grade Serous Ovarian Cancer (2020, Cancer Research)
  • Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway (2023, Cell)
  • Ultrasensitive Detection of Circulating LINE-1 ORF1p as a Specific Multicancer Biomarker (2023, Cancer Discovery)
  • Inaugurating High-Throughput Profiling of Extracellular Vesicles for Earlier Ovarian Cancer Detection (2023, Advanced Science)
  • Transient commensal clonal interactions can drive tumor metastasis (2020, Nature Communications)

Their frequent coauthors include Oladapo Yeku, David R. Spriggs, Eugene Kim, Yusuke Matoba, and Raj Kumar. Bo R. Rueda has contributed multiple publications to venues such as Cancer Research, bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Cancers, and Advanced Science. Cancer Research has been a notably frequent publication venue for their work.

Best Publications

  • Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance

    Jean Pierre Gillet;Anna Maria Calcagno;Sudhir Varma;Miguel Marino

  • Induction of interleukin-8 preserves the angiogenic response in HIF-1alpha-deficient colon cancer cells

    Yusuke Mizukami;Won-Seok Jo;Eva-Maria Duerr;Manish Gala

  • CD133 Expression Defines a Tumor Initiating Cell Population in Primary Human Ovarian Cancer

    Michael D. Curley;Vanessa A. Therrien;Christine L. Cummings;Petra A. Sergent

  • Leptin signaling promotes the growth of mammary tumors and increases the expression of vascular endothelial growth factor (VEGF) and its receptor type two (VEGF-R2).

    Ruben R. Gonzalez;Ruben R. Gonzalez;Salandre Cherfils;Maria Escobar;Jin H. Yoo

  • Caspase-3 gene knockout defines cell lineage specificity for programmed cell death signaling in the ovary.

    Tiina Matikainen;Gloria I. Perez;Timothy S. Zheng;Thomas R. Kluzak

  • The corpus luteum: an ovarian structure with maternal instincts and suicidal tendencies.

    John S. Davis;Bo R. Rueda

  • Characterization of twenty-five ovarian tumour cell lines that phenocopy primary tumours

    Tan A. Ince;Aurea D. Sousa;Michelle A. Jones;J. Chuck Harrell

  • HIF-1alpha and HIF-2alpha have divergent roles in colon cancer.

    Takaaki Imamura;Hirotoshi Kikuchi;Maria-Teresa Herraiz;Do-Youn Park

  • Ovarian cancer stem cell markers: prognostic and therapeutic implications.

    Daniela Burgos-Ojeda;Bo R. Rueda;Ronald J. Buckanovich

  • Caspase-3 is a pivotal mediator of apoptosis during regression of the ovarian corpus luteum.

    Silvia F. Carambula;Silvia F. Carambula;Tiina Matikainen;Maureen P. Lynch;Richard A. Flavell

  • Leptin-signaling inhibition results in efficient anti-tumor activity in estrogen receptor positive or negative breast cancer

    Ruben Rene Gonzalez;Ruben Rene Gonzalez;Ruben Rene Gonzalez;Amber Watters;Yanbo Xu;Udai P Singh

  • Increased bax and interleukin-1beta-converting enzyme messenger ribonucleic acid levels coincide with apoptosis in the bovine corpus luteum during structural regression.

    Bo R. Rueda;Kim I. Tilly;Ihab W. Botros;Peter D. Jolly

  • Ovarian cancer stem cells: working towards the root of stemness.

    Rosemary Foster;Ronald J. Buckanovich;Bo R. Rueda

  • Decreased Progesterone Levels and Progesterone Receptor Antagonists Promote Apoptotic Cell Death in Bovine Luteal Cells

    Bo R. Rueda;Isabel R. Hendry;William J. Hendry;Fredrick Stormshak

  • Constitutive Activation of Beta-Catenin in Uterine Stroma and Smooth Muscle Leads to the Development of Mesenchymal Tumors in Mice

    Pradeep S. Tanwar;Ho Joon Lee;Li Hua Zhang;Lawrence R. Zukerberg

  • Microvascular endothelial cells of the corpus luteum

    John S Davis;Bo R Rueda;Katherina Spanel-Borowski

  • Evidence for cancer stem cells in human endometrial carcinoma.

    Sonya A. Hubbard;Anne M. Friel;Beena Kumar;Ling Zhang

  • Prolonging the female reproductive lifespan and improving egg quality with dietary omega‐3 fatty acids

    Deepika Nehra;Hau D. Le;Hau D. Le;Erica M. Fallon;Erica M. Fallon;Sarah J. Carlson;Sarah J. Carlson

  • The Current Status of Evidence for and Against Postnatal Oogenesis in Mammals: A Case of Ovarian Optimism Versus Pessimism?

    Jonathan L. Tilly;Yuichi Niikura;Bo R. Rueda

  • Constitutive activation of beta-catenin in uterine stroma and smooth muscle leads to the development of mesenchymal tumors in mice Short title: Dysregulated β-catenin causes uterine tumors Summary Sentence: Mice develop uterine tumors that are similar to human tumors such as leiomyomas and endometrial stromal sarcomas if β-catenin is constitutively activated in early uterine mesenchyme.

    Pradeep S. Tanwar;Ho-Joon Lee;LiHua Zhang;Lawrence R. Zukerberg

Frequent Co-Authors

Jonathan L. Tilly
Jonathan L. Tilly Northeastern University
Ariane L. Herrick
Ariane L. Herrick University of Manchester
Jane Worthington
Jane Worthington University of Manchester
Esther Oliva
Esther Oliva Harvard University
Miguel A. López-Nevot
Miguel A. López-Nevot University of Granada
Daniel C. Chung
Daniel C. Chung Harvard University
Sandra Orsulic
Sandra Orsulic University of California, Los Angeles
José A. Teixeira
José A. Teixeira University of Minho
Patricia B. Hoyer
Patricia B. Hoyer University of Arizona
Paolo Airò
Paolo Airò University of Brescia

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