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Patricia K. Donahoe

Patricia K. Donahoe

D-Index & Metrics

Medicine

D-Index
95
Citations
34634
World Ranking
10036
National Ranking
5167

Research.com Recognitions

  • 1999 - Member of the National Academy of Sciences
  • 1998 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1991 - Member of the National Academy of Medicine (NAM)
  • 1987 - Fellow of the American Academy of Arts and Sciences

Overview

Patricia K. Donahoe is affiliated with Harvard University in the United States. Their research spans multiple fields with a focus on medicine and biochemistry, genetics, and molecular biology. Within these broad areas, key subfields of study include molecular biology, surgery, public health, environmental and occupational health, genetics, and reproductive medicine.

The scientist's research topics cover a range of areas related to reproductive biology, congenital diseases, and genetics. Major topics include reproductive biology and fertility, congenital diaphragmatic hernia studies, ovarian function and disorders, neonatal respiratory health research, renal and related cancers, genetic syndromes and imprinting, and RNA modifications and cancer.

Patricia K. Donahoe's publication record features notable recent papers such as:

  • "Antimullerian Hormone and Impending Menopause in Late Reproductive Age: The Study of Women's Health Across the Nation," 2020, The Journal of Clinical Endocrinology & Metabolism
  • "Single-cell sequencing reveals suppressive transcriptional programs regulated by MIS/AMH in neonatal ovaries," 2021, Proceedings of the National Academy of Sciences
  • "A single-cell atlas of the cycling murine ovary," 2022, eLife
  • "Structure of AMH bound to AMHR2 provides insight into a unique signaling pair in the TGF-β family," 2021, Proceedings of the National Academy of Sciences
  • "Rare and de novo variants in 827 congenital diaphragmatic hernia probands implicate LONP1 as candidate risk gene," 2021, The American Journal of Human Genetics

Frequent collaborators include:

  • David Pépin
  • Nicholas Nagykery
  • Frances A. High
  • Marie-Charlotte Meinsohn
  • Maëva Chauvin

The scientist's work has been published primarily in venues such as:

  • Proceedings of the National Academy of Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Fertility and Sterility
  • The American Journal of Human Genetics
  • Nature Communications

Patricia K. Donahoe has been recognized by election to several prestigious scientific bodies, including membership in the National Academy of Sciences since 1999 and the National Academy of Medicine since 1991. They are also a Fellow of the American Association for the Advancement of Science since 1998 and a Fellow of the American Academy of Arts and Sciences since 1987.

Best Publications

  • Detection of large-scale variation in the human genome.

    A John Iafrate;Lars Feuk;Miguel N Rivera;Miguel N Rivera;Marc L Listewnik

  • Isolation of the bovine and human genes for müllerian inhibiting substance and expression of the human gene in animal cells

    R.L. Cate;R.J. Mattaliano;C. Hession;R. Tizard

  • Activin receptor-like kinase 1 modulates transforming growth factor-β1 signaling in the regulation of angiogenesis

    S. Paul Oh;Tsugio Seki;Kendrick A. Goss;Takeshi Imamura

  • Ovarian cancer side population defines cells with stem cell-like characteristics and Mullerian Inhibiting Substance responsiveness

    Paul P. Szotek;Rafael Pieretti-Vanmarcke;Peter T. Masiakos;Daniela M. Dinulescu

  • Sex determination and differentiation.

    David T. MacLaughlin;Patricia K. Donahoe

  • Mullerian inhibiting substance in humans: normal levels from infancy to adulthood

    Mary M. Lee;Patricia K. Donahoe;Tomonobu Hasegawa;Bernard Silverman

  • The Immunophilin FKBP12 Functions as a Common Inhibitor of the TGFβ Family Type I Receptors

    Tongwen Wang;Bi-Yu Li;Paul D Danielson;Paresh C Shah

  • Mullerian Inhibiting Substance: A Gonadal Hormone with Multiple Functions

    Mary M. Lee;Patricia K. Donahoe

  • Specific interaction of type I receptors of the TGF-beta family with the immunophilin FKBP-12

    Tongwen Wang;Patricia K. Donahoe;Antonis S. Zervos

  • Comprehensive assessment of array-based platforms and calling algorithms for detection of copy number variants

    Dalila Pinto;Katayoon Darvishi;Xinghua Shi;Diana Rajan

  • A transforming growth factor beta type I receptor that signals to activate gene expression

    Craig H. Bassing;Jonathan M. Yingling;David J. Howe;Tongwen Wang

  • Müllerian inhibiting substance: an instructive developmental hormone with diagnostic and possible therapeutic applications.

    Jose Teixeira;Shyamala Maheswaran;Patricia K. Donahoe

  • An immunoassay to detect human müllerian inhibiting substance in males and females during normal development.

    Hudson Pl;Dougas I;Donahoe Pk;Cate Rl

  • Mutations in LRP2 , which encodes the multiligand receptor megalin, cause Donnai-Barrow and facio-oculo-acoustico-renal syndromes

    Sibel Kantarci;Lihadh Al-Gazali;R Sean Hill;R Sean Hill;Dian Donnai

  • Molecular basis of mammalian sexual determination: activation of Mullerian inhibiting substance gene expression by SRY

    Christopher M. Haqq;Chih Yen King;Etsuji Ukiyama;Sassan Falsafi

  • The type I serine/threonine kinase receptor ActRIA (ALK2) is required for gastrulation of the mouse embryo.

    Zhenyu Gu;E. M. Reynolds;Jihwan Song;H. Lei

  • A large-scale analysis of tissue-specific pathology and gene expression of human disease genes and complexes

    Kasper Lage;Niclas Tue Hansen;E. Olof Karlberg;Aron C. Eklund

  • The type I activin receptor ActRIB is required for egg cylinder organization and gastrulation in the mouse

    Zhenyu Gu;Masatoshi Nomura;Brenda B. Simpson;Hong Lei

  • Proteolytic processing of mullerian inhibiting substance produces a transforming growth factor-beta-like fragment.

    R B Pepinsky;L K Sinclair;E P Chow;R J Mattaliano

  • THE HORMONAL-CONTROL OF TESTICULAR DESCENT

    J. M. Hutson;P. K. Donahoe

Frequent Co-Authors

John M. Hutson
John M. Hutson Royal Children's Hospital
Kasper Lage
Kasper Lage Harvard University
Shyamala Maheswaran
Shyamala Maheswaran Harvard University
Frederic I. Preffer
Frederic I. Preffer Harvard University
David Dombkowski
David Dombkowski Harvard University
Charles Lee
Charles Lee The Jackson Laboratory
Christopher A. Walsh
Christopher A. Walsh Howard Hughes Medical Institute
Joseph P. Vacanti
Joseph P. Vacanti Harvard University
Guangping Gao
Guangping Gao University of Massachusetts Chan Medical School
Esther Oliva
Esther Oliva Harvard University

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